| Full name: chromosome 10 open reading frame 53 | Alias Symbol: Em:AC069546.1 | ||
| Type: protein-coding gene | Cytoband: 10q11.23 | ||
| Entrez ID: 282966 | HGNC ID: HGNC:27421 | Ensembl Gene: ENSG00000178645 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C10orf53:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C10orf53 | 282966 | 239998_at | 0.0580 | 0.8667 | |
| GSE26886 | C10orf53 | 282966 | 239998_at | 0.1099 | 0.3567 | |
| GSE45670 | C10orf53 | 282966 | 239998_at | 0.0819 | 0.4646 | |
| GSE53622 | C10orf53 | 282966 | 101293 | 0.3528 | 0.0001 | |
| GSE53624 | C10orf53 | 282966 | 101293 | 0.0623 | 0.4184 | |
| GSE63941 | C10orf53 | 282966 | 239998_at | 0.2962 | 0.0762 | |
| GSE77861 | C10orf53 | 282966 | 239998_at | -0.1618 | 0.1820 | |
| GSE97050 | C10orf53 | 282966 | A_33_P3325547 | 0.0213 | 0.9630 | |
| SRP133303 | C10orf53 | 282966 | RNAseq | 0.2639 | 0.0294 | |
| SRP159526 | C10orf53 | 282966 | RNAseq | 1.4188 | 0.0044 | |
| SRP193095 | C10orf53 | 282966 | RNAseq | 0.1125 | 0.5734 | |
| SRP219564 | C10orf53 | 282966 | RNAseq | -0.0048 | 0.9909 | |
| TCGA | C10orf53 | 282966 | RNAseq | 1.0646 | 0.6059 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C10orf53 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C10orf53:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C10orf53 | 282966 | 2 | 5 | 23 | |
| GSE20123 | C10orf53 | 282966 | 2 | 5 | 23 | |
| GSE43470 | C10orf53 | 282966 | 2 | 6 | 35 | |
| GSE46452 | C10orf53 | 282966 | 0 | 13 | 46 | |
| GSE47630 | C10orf53 | 282966 | 4 | 12 | 24 | |
| GSE54993 | C10orf53 | 282966 | 9 | 0 | 61 | |
| GSE54994 | C10orf53 | 282966 | 2 | 10 | 41 | |
| GSE60625 | C10orf53 | 282966 | 0 | 0 | 11 | |
| GSE74703 | C10orf53 | 282966 | 2 | 3 | 31 | |
| GSE74704 | C10orf53 | 282966 | 1 | 4 | 15 | |
| TCGA | C10orf53 | 282966 | 12 | 22 | 62 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of C10orf53:
Generating mutation plots.
Highly correlated genes for C10orf53:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C10orf53 | SCARNA2 | 0.643871 | 4 | 0 | 3 |
| C10orf53 | LYL1 | 0.643735 | 4 | 0 | 3 |
| C10orf53 | HOTTIP | 0.637909 | 3 | 0 | 3 |
| C10orf53 | TLDC2 | 0.637832 | 3 | 0 | 3 |
| C10orf53 | TGM6 | 0.629534 | 4 | 0 | 4 |
| C10orf53 | OR8D2 | 0.623749 | 3 | 0 | 3 |
| C10orf53 | TLX3 | 0.60875 | 4 | 0 | 3 |
| C10orf53 | RENBP | 0.60399 | 4 | 0 | 4 |
| C10orf53 | CBX8 | 0.60145 | 4 | 0 | 4 |
| C10orf53 | LINC01089 | 0.591568 | 3 | 0 | 3 |
| C10orf53 | VPS13A-AS1 | 0.58818 | 3 | 0 | 3 |
| C10orf53 | LINC01365 | 0.581855 | 4 | 0 | 3 |
| C10orf53 | CD33 | 0.581136 | 4 | 0 | 3 |
| C10orf53 | DCST2 | 0.576403 | 3 | 0 | 3 |
| C10orf53 | GLRA2 | 0.574761 | 4 | 0 | 4 |
| C10orf53 | CAPSL | 0.572401 | 3 | 0 | 3 |
| C10orf53 | CC2D2B | 0.566797 | 3 | 0 | 3 |
| C10orf53 | SLC4A1 | 0.566012 | 3 | 0 | 3 |
| C10orf53 | AQP10 | 0.565744 | 3 | 0 | 3 |
| C10orf53 | GTSF1L | 0.565644 | 5 | 0 | 3 |
For details and further investigation, click here
