| Full name: transglutaminase 6 | Alias Symbol: dJ734P14.3|TGY|SCA35 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 343641 | HGNC ID: HGNC:16255 | Ensembl Gene: ENSG00000166948 | OMIM ID: 613900 |
| Drug and gene relationship at DGIdb | |||
Expression of TGM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGM6 | 343641 | 233983_at | -0.1765 | 0.4022 | |
| GSE26886 | TGM6 | 343641 | 233983_at | -0.0241 | 0.8821 | |
| GSE45670 | TGM6 | 343641 | 233983_at | 0.0126 | 0.9178 | |
| GSE53622 | TGM6 | 343641 | 151396 | 0.0210 | 0.8424 | |
| GSE53624 | TGM6 | 343641 | 151396 | -0.3091 | 0.0003 | |
| GSE63941 | TGM6 | 343641 | 233983_at | 0.2566 | 0.1238 | |
| GSE77861 | TGM6 | 343641 | 233983_at | -0.1638 | 0.1838 | |
| GSE97050 | TGM6 | 343641 | A_33_P3249259 | -0.2782 | 0.3585 | |
| TCGA | TGM6 | 343641 | RNAseq | 4.4421 | 0.0041 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TGM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGM6 | 343641 | 12 | 3 | 15 | |
| GSE20123 | TGM6 | 343641 | 13 | 3 | 14 | |
| GSE43470 | TGM6 | 343641 | 11 | 1 | 31 | |
| GSE46452 | TGM6 | 343641 | 26 | 1 | 32 | |
| GSE47630 | TGM6 | 343641 | 18 | 4 | 18 | |
| GSE54993 | TGM6 | 343641 | 2 | 14 | 54 | |
| GSE54994 | TGM6 | 343641 | 24 | 2 | 27 | |
| GSE60625 | TGM6 | 343641 | 0 | 0 | 11 | |
| GSE74703 | TGM6 | 343641 | 10 | 1 | 25 | |
| GSE74704 | TGM6 | 343641 | 8 | 1 | 11 | |
| TCGA | TGM6 | 343641 | 40 | 11 | 45 |
Total number of gains: 164; Total number of losses: 41; Total Number of normals: 283.
Somatic mutations of TGM6:
Generating mutation plots.
Highly correlated genes for TGM6:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGM6 | MYO15B | 0.771002 | 3 | 0 | 3 |
| TGM6 | DUOXA2 | 0.745564 | 3 | 0 | 3 |
| TGM6 | LELP1 | 0.736009 | 4 | 0 | 4 |
| TGM6 | RAB17 | 0.729936 | 3 | 0 | 3 |
| TGM6 | SCN5A | 0.717106 | 3 | 0 | 3 |
| TGM6 | PAX2 | 0.711554 | 3 | 0 | 3 |
| TGM6 | GRIN1 | 0.709357 | 3 | 0 | 3 |
| TGM6 | PGC | 0.708169 | 3 | 0 | 3 |
| TGM6 | MYH13 | 0.706559 | 3 | 0 | 3 |
| TGM6 | GH1 | 0.704254 | 3 | 0 | 3 |
| TGM6 | PRRG3 | 0.702325 | 3 | 0 | 3 |
| TGM6 | RALYL | 0.701985 | 3 | 0 | 3 |
| TGM6 | GPR17 | 0.694999 | 4 | 0 | 3 |
| TGM6 | SIX3-AS1 | 0.693643 | 3 | 0 | 3 |
| TGM6 | HMGCLL1 | 0.685339 | 3 | 0 | 3 |
| TGM6 | TERT | 0.681434 | 3 | 0 | 3 |
| TGM6 | TUBA8 | 0.681046 | 4 | 0 | 4 |
| TGM6 | PKD2L1 | 0.680021 | 5 | 0 | 4 |
| TGM6 | B3GNT8 | 0.67804 | 3 | 0 | 3 |
| TGM6 | DOK7 | 0.678025 | 3 | 0 | 3 |
For details and further investigation, click here
