| Full name: TBC/LysM-associated domain containing 2 | Alias Symbol: dJ132F21.2 | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 140711 | HGNC ID: HGNC:16112 | Ensembl Gene: ENSG00000101342 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TLDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TLDC2 | 140711 | 233829_at | -0.0324 | 0.9245 | |
| GSE26886 | TLDC2 | 140711 | 233829_at | 0.1792 | 0.1244 | |
| GSE45670 | TLDC2 | 140711 | 233829_at | 0.0359 | 0.7765 | |
| GSE53622 | TLDC2 | 140711 | 31707 | -0.1923 | 0.1585 | |
| GSE53624 | TLDC2 | 140711 | 31707 | -0.1915 | 0.1421 | |
| GSE63941 | TLDC2 | 140711 | 233829_at | 0.3172 | 0.0810 | |
| GSE77861 | TLDC2 | 140711 | 233829_at | -0.1341 | 0.4084 | |
| SRP007169 | TLDC2 | 140711 | RNAseq | 1.4759 | 0.1038 | |
| SRP064894 | TLDC2 | 140711 | RNAseq | -0.0658 | 0.8675 | |
| SRP133303 | TLDC2 | 140711 | RNAseq | -0.7998 | 0.0004 | |
| SRP159526 | TLDC2 | 140711 | RNAseq | -0.1795 | 0.8009 | |
| SRP219564 | TLDC2 | 140711 | RNAseq | -0.2194 | 0.6856 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TLDC2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TLDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TLDC2 | 140711 | 14 | 2 | 14 | |
| GSE20123 | TLDC2 | 140711 | 14 | 2 | 14 | |
| GSE43470 | TLDC2 | 140711 | 12 | 0 | 31 | |
| GSE46452 | TLDC2 | 140711 | 29 | 0 | 30 | |
| GSE47630 | TLDC2 | 140711 | 24 | 0 | 16 | |
| GSE54993 | TLDC2 | 140711 | 0 | 17 | 53 | |
| GSE54994 | TLDC2 | 140711 | 24 | 0 | 29 | |
| GSE60625 | TLDC2 | 140711 | 0 | 0 | 11 | |
| GSE74703 | TLDC2 | 140711 | 11 | 0 | 25 | |
| GSE74704 | TLDC2 | 140711 | 10 | 1 | 9 | |
| TCGA | TLDC2 | 140711 | 47 | 3 | 46 |
Total number of gains: 185; Total number of losses: 25; Total Number of normals: 278.
Somatic mutations of TLDC2:
Generating mutation plots.
Highly correlated genes for TLDC2:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TLDC2 | LIMS2 | 0.660076 | 3 | 0 | 3 |
| TLDC2 | LINC01089 | 0.654789 | 3 | 0 | 3 |
| TLDC2 | TSPAN32 | 0.654427 | 3 | 0 | 3 |
| TLDC2 | PDZD7 | 0.65095 | 3 | 0 | 3 |
| TLDC2 | TCTN2 | 0.647651 | 3 | 0 | 3 |
| TLDC2 | CMA1 | 0.640268 | 3 | 0 | 3 |
| TLDC2 | LYL1 | 0.639121 | 3 | 0 | 3 |
| TLDC2 | C10orf53 | 0.637832 | 3 | 0 | 3 |
| TLDC2 | CACNA1A | 0.618027 | 3 | 0 | 3 |
| TLDC2 | PRDM8 | 0.617204 | 4 | 0 | 3 |
| TLDC2 | FSHB | 0.616047 | 4 | 0 | 4 |
| TLDC2 | MRGPRX4 | 0.615948 | 5 | 0 | 5 |
| TLDC2 | CRYAA | 0.613283 | 3 | 0 | 3 |
| TLDC2 | ZNF771 | 0.609525 | 4 | 0 | 4 |
| TLDC2 | MUC12 | 0.597286 | 3 | 0 | 3 |
| TLDC2 | CHCHD5 | 0.596232 | 4 | 0 | 3 |
| TLDC2 | APOM | 0.596174 | 3 | 0 | 3 |
| TLDC2 | SLC5A5 | 0.586431 | 3 | 0 | 3 |
| TLDC2 | DGCR10 | 0.578146 | 4 | 0 | 3 |
| TLDC2 | C6orf52 | 0.574175 | 3 | 0 | 3 |
For details and further investigation, click here
