| Full name: RNA binding motif protein 6 | Alias Symbol: DEF-3|3G2|NY-LU-12|g16|DEF3 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 10180 | HGNC ID: HGNC:9903 | Ensembl Gene: ENSG00000004534 | OMIM ID: 606886 |
| Drug and gene relationship at DGIdb | |||
Expression of RBM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM6 | 10180 | 201967_at | -0.1881 | 0.7943 | |
| GSE20347 | RBM6 | 10180 | 201967_at | -0.2955 | 0.0558 | |
| GSE23400 | RBM6 | 10180 | 201967_at | -0.2252 | 0.0008 | |
| GSE26886 | RBM6 | 10180 | 228030_at | -3.0756 | 0.0000 | |
| GSE29001 | RBM6 | 10180 | 201967_at | -0.2772 | 0.4447 | |
| GSE38129 | RBM6 | 10180 | 201967_at | -0.4420 | 0.0021 | |
| GSE45670 | RBM6 | 10180 | 201967_at | -0.1653 | 0.2838 | |
| GSE53622 | RBM6 | 10180 | 85848 | -0.3395 | 0.0000 | |
| GSE53624 | RBM6 | 10180 | 46514 | -0.5645 | 0.0000 | |
| GSE63941 | RBM6 | 10180 | 201967_at | -0.6923 | 0.0099 | |
| GSE77861 | RBM6 | 10180 | 201967_at | -0.1861 | 0.3381 | |
| GSE97050 | RBM6 | 10180 | A_23_P57941 | -0.3426 | 0.2536 | |
| SRP007169 | RBM6 | 10180 | RNAseq | -0.0628 | 0.9044 | |
| SRP008496 | RBM6 | 10180 | RNAseq | 0.1178 | 0.7503 | |
| SRP064894 | RBM6 | 10180 | RNAseq | 0.0319 | 0.8524 | |
| SRP133303 | RBM6 | 10180 | RNAseq | -0.4222 | 0.0005 | |
| SRP159526 | RBM6 | 10180 | RNAseq | -0.3992 | 0.2677 | |
| SRP193095 | RBM6 | 10180 | RNAseq | -0.3333 | 0.0007 | |
| SRP219564 | RBM6 | 10180 | RNAseq | -0.0535 | 0.9063 | |
| TCGA | RBM6 | 10180 | RNAseq | -0.2193 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RBM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM6 | 10180 | 0 | 18 | 12 | |
| GSE20123 | RBM6 | 10180 | 0 | 19 | 11 | |
| GSE43470 | RBM6 | 10180 | 0 | 18 | 25 | |
| GSE46452 | RBM6 | 10180 | 2 | 16 | 41 | |
| GSE47630 | RBM6 | 10180 | 1 | 24 | 15 | |
| GSE54993 | RBM6 | 10180 | 6 | 2 | 62 | |
| GSE54994 | RBM6 | 10180 | 0 | 34 | 19 | |
| GSE60625 | RBM6 | 10180 | 5 | 0 | 6 | |
| GSE74703 | RBM6 | 10180 | 0 | 14 | 22 | |
| GSE74704 | RBM6 | 10180 | 0 | 12 | 8 | |
| TCGA | RBM6 | 10180 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 234; Total Number of normals: 240.
Somatic mutations of RBM6:
Generating mutation plots.
Highly correlated genes for RBM6:
Showing top 20/487 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM6 | ZBTB4 | 0.794775 | 3 | 0 | 3 |
| RBM6 | C19orf18 | 0.742209 | 3 | 0 | 3 |
| RBM6 | ZNF583 | 0.731613 | 3 | 0 | 3 |
| RBM6 | WWP1 | 0.731391 | 3 | 0 | 3 |
| RBM6 | PITHD1 | 0.728405 | 3 | 0 | 3 |
| RBM6 | UBXN1 | 0.719753 | 3 | 0 | 3 |
| RBM6 | EPB41 | 0.714039 | 3 | 0 | 3 |
| RBM6 | TMEM181 | 0.711711 | 3 | 0 | 3 |
| RBM6 | SYMPK | 0.7115 | 4 | 0 | 4 |
| RBM6 | DPCD | 0.70705 | 3 | 0 | 3 |
| RBM6 | OXNAD1 | 0.702037 | 3 | 0 | 3 |
| RBM6 | CDC16 | 0.69324 | 4 | 0 | 4 |
| RBM6 | UBR3 | 0.687609 | 3 | 0 | 3 |
| RBM6 | C5orf51 | 0.682717 | 4 | 0 | 3 |
| RBM6 | EFHC1 | 0.682475 | 3 | 0 | 3 |
| RBM6 | RNF11 | 0.681564 | 3 | 0 | 3 |
| RBM6 | MTPN | 0.679102 | 3 | 0 | 3 |
| RBM6 | TMEM25 | 0.678189 | 3 | 0 | 3 |
| RBM6 | RBM5 | 0.673472 | 12 | 0 | 10 |
| RBM6 | DEF8 | 0.672459 | 3 | 0 | 3 |
For details and further investigation, click here
