| Full name: chromosome 2 open reading frame 49 | Alias Symbol: MGC5509|asw | ||
| Type: protein-coding gene | Cytoband: 2q12.2 | ||
| Entrez ID: 79074 | HGNC ID: HGNC:28772 | Ensembl Gene: ENSG00000135974 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C2orf49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2orf49 | 79074 | 226951_at | 0.1255 | 0.7951 | |
| GSE20347 | C2orf49 | 79074 | 219662_at | -0.3213 | 0.1407 | |
| GSE23400 | C2orf49 | 79074 | 219662_at | 0.0069 | 0.8859 | |
| GSE26886 | C2orf49 | 79074 | 226951_at | 0.0161 | 0.9624 | |
| GSE29001 | C2orf49 | 79074 | 219662_at | -0.2298 | 0.5144 | |
| GSE38129 | C2orf49 | 79074 | 219662_at | 0.0237 | 0.9081 | |
| GSE45670 | C2orf49 | 79074 | 226951_at | -0.2742 | 0.0901 | |
| GSE53622 | C2orf49 | 79074 | 18922 | -0.0766 | 0.1764 | |
| GSE53624 | C2orf49 | 79074 | 18922 | 0.1007 | 0.0821 | |
| GSE63941 | C2orf49 | 79074 | 219662_at | 0.7422 | 0.1861 | |
| GSE77861 | C2orf49 | 79074 | 219662_at | -0.1739 | 0.4750 | |
| GSE97050 | C2orf49 | 79074 | A_23_P165698 | -0.3804 | 0.1878 | |
| SRP007169 | C2orf49 | 79074 | RNAseq | 0.0451 | 0.8982 | |
| SRP008496 | C2orf49 | 79074 | RNAseq | 0.2453 | 0.3449 | |
| SRP064894 | C2orf49 | 79074 | RNAseq | -0.2318 | 0.1811 | |
| SRP133303 | C2orf49 | 79074 | RNAseq | -0.1066 | 0.4170 | |
| SRP159526 | C2orf49 | 79074 | RNAseq | 0.0052 | 0.9800 | |
| SRP193095 | C2orf49 | 79074 | RNAseq | -0.0269 | 0.8301 | |
| SRP219564 | C2orf49 | 79074 | RNAseq | -0.4678 | 0.0733 | |
| TCGA | C2orf49 | 79074 | RNAseq | 0.0363 | 0.5832 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C2orf49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2orf49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2orf49 | 79074 | 3 | 2 | 25 | |
| GSE20123 | C2orf49 | 79074 | 3 | 2 | 25 | |
| GSE43470 | C2orf49 | 79074 | 3 | 1 | 39 | |
| GSE46452 | C2orf49 | 79074 | 1 | 4 | 54 | |
| GSE47630 | C2orf49 | 79074 | 7 | 0 | 33 | |
| GSE54993 | C2orf49 | 79074 | 0 | 6 | 64 | |
| GSE54994 | C2orf49 | 79074 | 10 | 0 | 43 | |
| GSE60625 | C2orf49 | 79074 | 0 | 3 | 8 | |
| GSE74703 | C2orf49 | 79074 | 3 | 1 | 32 | |
| GSE74704 | C2orf49 | 79074 | 2 | 2 | 16 | |
| TCGA | C2orf49 | 79074 | 34 | 5 | 57 |
Total number of gains: 66; Total number of losses: 26; Total Number of normals: 396.
Somatic mutations of C2orf49:
Generating mutation plots.
Highly correlated genes for C2orf49:
Showing top 20/394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2orf49 | ZFYVE26 | 0.7862 | 3 | 0 | 3 |
| C2orf49 | AMD1 | 0.774723 | 3 | 0 | 3 |
| C2orf49 | ZNF317 | 0.748183 | 3 | 0 | 3 |
| C2orf49 | ZCCHC8 | 0.743989 | 3 | 0 | 3 |
| C2orf49 | ZNF565 | 0.727978 | 3 | 0 | 3 |
| C2orf49 | CARS2 | 0.727777 | 3 | 0 | 3 |
| C2orf49 | PSMD5 | 0.724329 | 3 | 0 | 3 |
| C2orf49 | CDC42BPA | 0.717844 | 3 | 0 | 3 |
| C2orf49 | ANAPC4 | 0.716717 | 3 | 0 | 3 |
| C2orf49 | COCH | 0.706876 | 3 | 0 | 3 |
| C2orf49 | CTDSPL | 0.705219 | 4 | 0 | 3 |
| C2orf49 | LSM11 | 0.704213 | 3 | 0 | 3 |
| C2orf49 | PARP4 | 0.702732 | 3 | 0 | 3 |
| C2orf49 | CHMP4B | 0.701393 | 3 | 0 | 3 |
| C2orf49 | ZSCAN16 | 0.70042 | 3 | 0 | 3 |
| C2orf49 | TTC37 | 0.698984 | 4 | 0 | 4 |
| C2orf49 | NUDT19 | 0.696802 | 3 | 0 | 3 |
| C2orf49 | CLPP | 0.68992 | 3 | 0 | 3 |
| C2orf49 | ZBTB26 | 0.688516 | 4 | 0 | 3 |
| C2orf49 | SLAIN1 | 0.685759 | 3 | 0 | 3 |
For details and further investigation, click here
