| Full name: zinc finger CCHC-type containing 8 | Alias Symbol: DKFZp434E2220 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 55596 | HGNC ID: HGNC:25265 | Ensembl Gene: ENSG00000033030 | OMIM ID: 616381 |
| Drug and gene relationship at DGIdb | |||
Expression of ZCCHC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZCCHC8 | 55596 | 218478_s_at | 0.0109 | 0.9801 | |
| GSE20347 | ZCCHC8 | 55596 | 218478_s_at | 0.0027 | 0.9864 | |
| GSE23400 | ZCCHC8 | 55596 | 218478_s_at | 0.1353 | 0.0532 | |
| GSE26886 | ZCCHC8 | 55596 | 218478_s_at | -0.4421 | 0.0668 | |
| GSE29001 | ZCCHC8 | 55596 | 218478_s_at | 0.1429 | 0.5307 | |
| GSE38129 | ZCCHC8 | 55596 | 218478_s_at | 0.0962 | 0.4895 | |
| GSE45670 | ZCCHC8 | 55596 | 218478_s_at | 0.0965 | 0.3487 | |
| GSE53622 | ZCCHC8 | 55596 | 91545 | 0.1690 | 0.0062 | |
| GSE53624 | ZCCHC8 | 55596 | 91545 | 0.1465 | 0.0160 | |
| GSE63941 | ZCCHC8 | 55596 | 218478_s_at | 1.2405 | 0.0034 | |
| GSE77861 | ZCCHC8 | 55596 | 218478_s_at | 0.1034 | 0.6265 | |
| GSE97050 | ZCCHC8 | 55596 | A_23_P64669 | 0.0203 | 0.9338 | |
| SRP007169 | ZCCHC8 | 55596 | RNAseq | -0.3049 | 0.4162 | |
| SRP008496 | ZCCHC8 | 55596 | RNAseq | -0.3038 | 0.2110 | |
| SRP064894 | ZCCHC8 | 55596 | RNAseq | -0.2050 | 0.3377 | |
| SRP133303 | ZCCHC8 | 55596 | RNAseq | 0.1673 | 0.1471 | |
| SRP159526 | ZCCHC8 | 55596 | RNAseq | 0.0594 | 0.7687 | |
| SRP193095 | ZCCHC8 | 55596 | RNAseq | -0.0450 | 0.5752 | |
| SRP219564 | ZCCHC8 | 55596 | RNAseq | -0.1407 | 0.7102 | |
| TCGA | ZCCHC8 | 55596 | RNAseq | 0.0736 | 0.1700 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZCCHC8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZCCHC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZCCHC8 | 55596 | 5 | 4 | 21 | |
| GSE20123 | ZCCHC8 | 55596 | 5 | 4 | 21 | |
| GSE43470 | ZCCHC8 | 55596 | 2 | 1 | 40 | |
| GSE46452 | ZCCHC8 | 55596 | 9 | 1 | 49 | |
| GSE47630 | ZCCHC8 | 55596 | 9 | 3 | 28 | |
| GSE54993 | ZCCHC8 | 55596 | 0 | 5 | 65 | |
| GSE54994 | ZCCHC8 | 55596 | 5 | 7 | 41 | |
| GSE60625 | ZCCHC8 | 55596 | 0 | 0 | 11 | |
| GSE74703 | ZCCHC8 | 55596 | 2 | 0 | 34 | |
| GSE74704 | ZCCHC8 | 55596 | 4 | 2 | 14 | |
| TCGA | ZCCHC8 | 55596 | 21 | 10 | 65 |
Total number of gains: 62; Total number of losses: 37; Total Number of normals: 389.
Somatic mutations of ZCCHC8:
Generating mutation plots.
Highly correlated genes for ZCCHC8:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZCCHC8 | PPCS | 0.8298 | 3 | 0 | 3 |
| ZCCHC8 | RRAGC | 0.79957 | 3 | 0 | 3 |
| ZCCHC8 | BRAP | 0.792413 | 3 | 0 | 3 |
| ZCCHC8 | GIN1 | 0.770064 | 3 | 0 | 3 |
| ZCCHC8 | ZNF436 | 0.769 | 3 | 0 | 3 |
| ZCCHC8 | PLA2G12A | 0.764888 | 3 | 0 | 3 |
| ZCCHC8 | TTI2 | 0.762921 | 3 | 0 | 3 |
| ZCCHC8 | B3GNT2 | 0.757471 | 3 | 0 | 3 |
| ZCCHC8 | ARGLU1 | 0.756869 | 3 | 0 | 3 |
| ZCCHC8 | CMTM4 | 0.752199 | 3 | 0 | 3 |
| ZCCHC8 | CREBZF | 0.751216 | 3 | 0 | 3 |
| ZCCHC8 | MRPL10 | 0.749942 | 3 | 0 | 3 |
| ZCCHC8 | IAH1 | 0.748909 | 3 | 0 | 3 |
| ZCCHC8 | GNL3 | 0.747036 | 3 | 0 | 3 |
| ZCCHC8 | NAA20 | 0.745781 | 3 | 0 | 3 |
| ZCCHC8 | C2orf49 | 0.743989 | 3 | 0 | 3 |
| ZCCHC8 | TMCO4 | 0.738995 | 3 | 0 | 3 |
| ZCCHC8 | NUDT21 | 0.73589 | 3 | 0 | 3 |
| ZCCHC8 | ARID2 | 0.73371 | 3 | 0 | 3 |
| ZCCHC8 | LARP1B | 0.732984 | 3 | 0 | 3 |
For details and further investigation, click here
