| Full name: chromosome 2 open reading frame 88 | Alias Symbol: MGC13057|smAKAP | ||
| Type: protein-coding gene | Cytoband: 2q32.2 | ||
| Entrez ID: 84281 | HGNC ID: HGNC:28191 | Ensembl Gene: ENSG00000187699 | OMIM ID: 615117 |
| Drug and gene relationship at DGIdb | |||
Expression of C2orf88:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2orf88 | 84281 | 223754_at | 0.0366 | 0.9422 | |
| GSE26886 | C2orf88 | 84281 | 223754_at | 0.2412 | 0.0978 | |
| GSE45670 | C2orf88 | 84281 | 228195_at | -0.6440 | 0.0008 | |
| GSE53622 | C2orf88 | 84281 | 120427 | -0.9191 | 0.0000 | |
| GSE53624 | C2orf88 | 84281 | 120427 | -0.8467 | 0.0000 | |
| GSE63941 | C2orf88 | 84281 | 223754_at | -0.1354 | 0.6320 | |
| GSE77861 | C2orf88 | 84281 | 223754_at | 0.0105 | 0.9364 | |
| GSE97050 | C2orf88 | 84281 | A_23_P17130 | -0.5368 | 0.1740 | |
| SRP007169 | C2orf88 | 84281 | RNAseq | 0.4412 | 0.5805 | |
| SRP064894 | C2orf88 | 84281 | RNAseq | 0.0006 | 0.9985 | |
| SRP133303 | C2orf88 | 84281 | RNAseq | -0.6531 | 0.0000 | |
| SRP159526 | C2orf88 | 84281 | RNAseq | -0.0671 | 0.8374 | |
| SRP193095 | C2orf88 | 84281 | RNAseq | -1.0387 | 0.0000 | |
| SRP219564 | C2orf88 | 84281 | RNAseq | -0.7517 | 0.3208 | |
| TCGA | C2orf88 | 84281 | RNAseq | -0.9909 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C2orf88 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2orf88:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2orf88 | 84281 | 8 | 2 | 20 | |
| GSE20123 | C2orf88 | 84281 | 8 | 2 | 20 | |
| GSE43470 | C2orf88 | 84281 | 3 | 1 | 39 | |
| GSE46452 | C2orf88 | 84281 | 1 | 4 | 54 | |
| GSE47630 | C2orf88 | 84281 | 4 | 5 | 31 | |
| GSE54993 | C2orf88 | 84281 | 0 | 5 | 65 | |
| GSE54994 | C2orf88 | 84281 | 12 | 6 | 35 | |
| GSE60625 | C2orf88 | 84281 | 0 | 3 | 8 | |
| GSE74703 | C2orf88 | 84281 | 2 | 1 | 33 | |
| GSE74704 | C2orf88 | 84281 | 3 | 2 | 15 | |
| TCGA | C2orf88 | 84281 | 23 | 7 | 66 |
Total number of gains: 64; Total number of losses: 38; Total Number of normals: 386.
Somatic mutations of C2orf88:
Generating mutation plots.
Highly correlated genes for C2orf88:
Showing top 20/502 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2orf88 | TBC1D17 | 0.777694 | 3 | 0 | 3 |
| C2orf88 | GNA11 | 0.768757 | 3 | 0 | 3 |
| C2orf88 | PIP5K1C | 0.741149 | 3 | 0 | 3 |
| C2orf88 | TNFSF12 | 0.740264 | 3 | 0 | 3 |
| C2orf88 | POGZ | 0.739379 | 3 | 0 | 3 |
| C2orf88 | OGN | 0.730598 | 4 | 0 | 4 |
| C2orf88 | PREX2 | 0.728929 | 3 | 0 | 3 |
| C2orf88 | ADCY6 | 0.728031 | 3 | 0 | 3 |
| C2orf88 | C1QTNF7 | 0.726998 | 4 | 0 | 4 |
| C2orf88 | EID1 | 0.726843 | 3 | 0 | 3 |
| C2orf88 | LGI2 | 0.71897 | 4 | 0 | 3 |
| C2orf88 | PEG10 | 0.71715 | 3 | 0 | 3 |
| C2orf88 | MEIS2 | 0.713571 | 4 | 0 | 4 |
| C2orf88 | MYOCD | 0.711767 | 3 | 0 | 3 |
| C2orf88 | ITM2A | 0.71084 | 4 | 0 | 4 |
| C2orf88 | BEGAIN | 0.706995 | 3 | 0 | 3 |
| C2orf88 | FHL5 | 0.706798 | 5 | 0 | 5 |
| C2orf88 | SPRY1 | 0.704715 | 3 | 0 | 3 |
| C2orf88 | MAN1C1 | 0.704646 | 4 | 0 | 4 |
| C2orf88 | NR4A1 | 0.703058 | 4 | 0 | 4 |
For details and further investigation, click here
