| Full name: phosphatidylinositol-4-phosphate 5-kinase type 1 gamma | Alias Symbol: PIP5Kgamma|KIAA0589|LCCS3 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 23396 | HGNC ID: HGNC:8996 | Ensembl Gene: ENSG00000186111 | OMIM ID: 606102 |
| Drug and gene relationship at DGIdb | |||
PIP5K1C involved pathways:
Expression of PIP5K1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIP5K1C | 23396 | 212518_at | -0.3176 | 0.4939 | |
| GSE20347 | PIP5K1C | 23396 | 212518_at | 0.0160 | 0.8755 | |
| GSE23400 | PIP5K1C | 23396 | 212518_at | -0.2812 | 0.0005 | |
| GSE26886 | PIP5K1C | 23396 | 212518_at | 0.3125 | 0.0468 | |
| GSE29001 | PIP5K1C | 23396 | 212518_at | -0.0876 | 0.7902 | |
| GSE38129 | PIP5K1C | 23396 | 212518_at | -0.2676 | 0.0291 | |
| GSE45670 | PIP5K1C | 23396 | 212518_at | -0.0973 | 0.1777 | |
| GSE53622 | PIP5K1C | 23396 | 18053 | -0.3530 | 0.0002 | |
| GSE53624 | PIP5K1C | 23396 | 18053 | -0.1435 | 0.0207 | |
| GSE63941 | PIP5K1C | 23396 | 212518_at | -0.1905 | 0.6553 | |
| GSE77861 | PIP5K1C | 23396 | 212518_at | 0.1055 | 0.4783 | |
| GSE97050 | PIP5K1C | 23396 | A_23_P330262 | -0.3789 | 0.2090 | |
| SRP007169 | PIP5K1C | 23396 | RNAseq | -1.0320 | 0.0194 | |
| SRP008496 | PIP5K1C | 23396 | RNAseq | -0.8281 | 0.0031 | |
| SRP064894 | PIP5K1C | 23396 | RNAseq | -0.0774 | 0.7054 | |
| SRP133303 | PIP5K1C | 23396 | RNAseq | -0.1379 | 0.5075 | |
| SRP159526 | PIP5K1C | 23396 | RNAseq | -0.2970 | 0.1931 | |
| SRP193095 | PIP5K1C | 23396 | RNAseq | -0.0077 | 0.9614 | |
| SRP219564 | PIP5K1C | 23396 | RNAseq | -0.1699 | 0.7427 | |
| TCGA | PIP5K1C | 23396 | RNAseq | -0.2245 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PIP5K1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIP5K1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIP5K1C | 23396 | 5 | 3 | 22 | |
| GSE20123 | PIP5K1C | 23396 | 4 | 2 | 24 | |
| GSE43470 | PIP5K1C | 23396 | 1 | 9 | 33 | |
| GSE46452 | PIP5K1C | 23396 | 47 | 1 | 11 | |
| GSE47630 | PIP5K1C | 23396 | 5 | 7 | 28 | |
| GSE54993 | PIP5K1C | 23396 | 16 | 3 | 51 | |
| GSE54994 | PIP5K1C | 23396 | 8 | 16 | 29 | |
| GSE60625 | PIP5K1C | 23396 | 9 | 0 | 2 | |
| GSE74703 | PIP5K1C | 23396 | 1 | 6 | 29 | |
| GSE74704 | PIP5K1C | 23396 | 1 | 2 | 17 | |
| TCGA | PIP5K1C | 23396 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 68; Total Number of normals: 313.
Somatic mutations of PIP5K1C:
Generating mutation plots.
Highly correlated genes for PIP5K1C:
Showing top 20/926 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIP5K1C | NHSL2 | 0.803805 | 3 | 0 | 3 |
| PIP5K1C | XKR4 | 0.801651 | 3 | 0 | 3 |
| PIP5K1C | SSC5D | 0.79116 | 3 | 0 | 3 |
| PIP5K1C | CYP2U1 | 0.770799 | 3 | 0 | 3 |
| PIP5K1C | IQUB | 0.765473 | 3 | 0 | 3 |
| PIP5K1C | TMOD1 | 0.76506 | 5 | 0 | 4 |
| PIP5K1C | ANO5 | 0.764149 | 3 | 0 | 3 |
| PIP5K1C | SORCS1 | 0.762178 | 3 | 0 | 3 |
| PIP5K1C | TRIM47 | 0.760148 | 3 | 0 | 3 |
| PIP5K1C | SOX10 | 0.758959 | 3 | 0 | 3 |
| PIP5K1C | KLHL15 | 0.758303 | 3 | 0 | 3 |
| PIP5K1C | PLIN4 | 0.756679 | 4 | 0 | 4 |
| PIP5K1C | SYNC | 0.755923 | 4 | 0 | 4 |
| PIP5K1C | NAP1L5 | 0.75352 | 3 | 0 | 3 |
| PIP5K1C | LRFN5 | 0.748129 | 3 | 0 | 3 |
| PIP5K1C | ZNF787 | 0.747165 | 3 | 0 | 3 |
| PIP5K1C | R3HDM2 | 0.743601 | 4 | 0 | 3 |
| PIP5K1C | RAB7A | 0.74137 | 3 | 0 | 3 |
| PIP5K1C | C2orf88 | 0.741149 | 3 | 0 | 3 |
| PIP5K1C | RASL12 | 0.738755 | 7 | 0 | 6 |
For details and further investigation, click here
