| Full name: brain enriched guanylate kinase associated | Alias Symbol: KIAA1446 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 57596 | HGNC ID: HGNC:24163 | Ensembl Gene: ENSG00000183092 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BEGAIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BEGAIN | 57596 | 220795_s_at | -0.2597 | 0.3119 | |
| GSE20347 | BEGAIN | 57596 | 220795_s_at | -0.0240 | 0.8160 | |
| GSE23400 | BEGAIN | 57596 | 220795_s_at | -0.1488 | 0.0025 | |
| GSE26886 | BEGAIN | 57596 | 220795_s_at | 0.4781 | 0.0034 | |
| GSE29001 | BEGAIN | 57596 | 220795_s_at | 0.2017 | 0.5244 | |
| GSE38129 | BEGAIN | 57596 | 220795_s_at | -0.1818 | 0.1919 | |
| GSE45670 | BEGAIN | 57596 | 220795_s_at | -0.1588 | 0.1170 | |
| GSE53622 | BEGAIN | 57596 | 43995 | 0.0007 | 0.9971 | |
| GSE53624 | BEGAIN | 57596 | 43995 | 0.2884 | 0.0339 | |
| GSE63941 | BEGAIN | 57596 | 220795_s_at | 0.7075 | 0.2540 | |
| GSE77861 | BEGAIN | 57596 | 220795_s_at | -0.0971 | 0.6129 | |
| GSE97050 | BEGAIN | 57596 | A_33_P3321205 | -0.0125 | 0.9694 | |
| SRP133303 | BEGAIN | 57596 | RNAseq | 0.2944 | 0.4090 | |
| SRP159526 | BEGAIN | 57596 | RNAseq | 1.6286 | 0.0069 | |
| TCGA | BEGAIN | 57596 | RNAseq | -0.3576 | 0.1332 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BEGAIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BEGAIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BEGAIN | 57596 | 9 | 5 | 16 | |
| GSE20123 | BEGAIN | 57596 | 9 | 4 | 17 | |
| GSE43470 | BEGAIN | 57596 | 7 | 4 | 32 | |
| GSE46452 | BEGAIN | 57596 | 17 | 3 | 39 | |
| GSE47630 | BEGAIN | 57596 | 11 | 8 | 21 | |
| GSE54993 | BEGAIN | 57596 | 3 | 8 | 59 | |
| GSE54994 | BEGAIN | 57596 | 21 | 4 | 28 | |
| GSE60625 | BEGAIN | 57596 | 0 | 2 | 9 | |
| GSE74703 | BEGAIN | 57596 | 6 | 3 | 27 | |
| GSE74704 | BEGAIN | 57596 | 5 | 3 | 12 | |
| TCGA | BEGAIN | 57596 | 32 | 17 | 47 |
Total number of gains: 120; Total number of losses: 61; Total Number of normals: 307.
Somatic mutations of BEGAIN:
Generating mutation plots.
Highly correlated genes for BEGAIN:
Showing top 20/473 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BEGAIN | CYYR1 | 0.841914 | 3 | 0 | 3 |
| BEGAIN | PITPNM2 | 0.778052 | 3 | 0 | 3 |
| BEGAIN | PLCD3 | 0.770615 | 3 | 0 | 3 |
| BEGAIN | PARP16 | 0.767605 | 3 | 0 | 3 |
| BEGAIN | UBXN10 | 0.758314 | 3 | 0 | 3 |
| BEGAIN | ACY1 | 0.755658 | 3 | 0 | 3 |
| BEGAIN | SF3A1 | 0.752663 | 3 | 0 | 3 |
| BEGAIN | CHADL | 0.751632 | 3 | 0 | 3 |
| BEGAIN | HSPB7 | 0.748616 | 3 | 0 | 3 |
| BEGAIN | NHSL2 | 0.744433 | 3 | 0 | 3 |
| BEGAIN | RNF207 | 0.736663 | 3 | 0 | 3 |
| BEGAIN | HMCN1 | 0.735263 | 3 | 0 | 3 |
| BEGAIN | ADPRH | 0.73307 | 3 | 0 | 3 |
| BEGAIN | COL23A1 | 0.729575 | 3 | 0 | 3 |
| BEGAIN | NFAM1 | 0.722211 | 3 | 0 | 3 |
| BEGAIN | PPP1R1B | 0.714268 | 3 | 0 | 3 |
| BEGAIN | FILIP1 | 0.711524 | 4 | 0 | 3 |
| BEGAIN | KLHL13 | 0.711446 | 3 | 0 | 3 |
| BEGAIN | TAF6 | 0.709577 | 3 | 0 | 3 |
| BEGAIN | CLCC1 | 0.708643 | 3 | 0 | 3 |
For details and further investigation, click here
