| Full name: TBC1 domain family member 17 | Alias Symbol: FLJ12168 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 79735 | HGNC ID: HGNC:25699 | Ensembl Gene: ENSG00000104946 | OMIM ID: 616659 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D17 | 79735 | 218466_at | -0.0150 | 0.9813 | |
| GSE20347 | TBC1D17 | 79735 | 218466_at | -0.1172 | 0.4030 | |
| GSE23400 | TBC1D17 | 79735 | 218466_at | 0.0595 | 0.4644 | |
| GSE26886 | TBC1D17 | 79735 | 218466_at | 0.2927 | 0.1206 | |
| GSE29001 | TBC1D17 | 79735 | 218466_at | -0.0246 | 0.8942 | |
| GSE38129 | TBC1D17 | 79735 | 218466_at | -0.1437 | 0.2116 | |
| GSE45670 | TBC1D17 | 79735 | 218466_at | -0.1361 | 0.1849 | |
| GSE53622 | TBC1D17 | 79735 | 94776 | -0.4606 | 0.0000 | |
| GSE53624 | TBC1D17 | 79735 | 65332 | -0.7843 | 0.0000 | |
| GSE63941 | TBC1D17 | 79735 | 218466_at | 0.6039 | 0.1321 | |
| GSE77861 | TBC1D17 | 79735 | 218466_at | 0.0086 | 0.9771 | |
| GSE97050 | TBC1D17 | 79735 | A_23_P130731 | -0.4802 | 0.1623 | |
| SRP007169 | TBC1D17 | 79735 | RNAseq | -1.0901 | 0.0029 | |
| SRP008496 | TBC1D17 | 79735 | RNAseq | -0.9663 | 0.0001 | |
| SRP064894 | TBC1D17 | 79735 | RNAseq | 0.1449 | 0.4837 | |
| SRP133303 | TBC1D17 | 79735 | RNAseq | -0.2954 | 0.0737 | |
| SRP159526 | TBC1D17 | 79735 | RNAseq | 0.3553 | 0.4153 | |
| SRP193095 | TBC1D17 | 79735 | RNAseq | 0.2275 | 0.2062 | |
| SRP219564 | TBC1D17 | 79735 | RNAseq | -0.2889 | 0.4533 | |
| TCGA | TBC1D17 | 79735 | RNAseq | -0.1660 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TBC1D17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D17 | 79735 | 4 | 4 | 22 | |
| GSE20123 | TBC1D17 | 79735 | 4 | 3 | 23 | |
| GSE43470 | TBC1D17 | 79735 | 5 | 11 | 27 | |
| GSE46452 | TBC1D17 | 79735 | 45 | 1 | 13 | |
| GSE47630 | TBC1D17 | 79735 | 10 | 6 | 24 | |
| GSE54993 | TBC1D17 | 79735 | 17 | 4 | 49 | |
| GSE54994 | TBC1D17 | 79735 | 4 | 14 | 35 | |
| GSE60625 | TBC1D17 | 79735 | 9 | 0 | 2 | |
| GSE74703 | TBC1D17 | 79735 | 5 | 7 | 24 | |
| GSE74704 | TBC1D17 | 79735 | 4 | 1 | 15 | |
| TCGA | TBC1D17 | 79735 | 14 | 18 | 64 |
Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.
Somatic mutations of TBC1D17:
Generating mutation plots.
Highly correlated genes for TBC1D17:
Showing top 20/386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D17 | RCOR3 | 0.810966 | 3 | 0 | 3 |
| TBC1D17 | C2orf88 | 0.777694 | 3 | 0 | 3 |
| TBC1D17 | CDRT15L2 | 0.744945 | 3 | 0 | 3 |
| TBC1D17 | DIRAS1 | 0.741346 | 3 | 0 | 3 |
| TBC1D17 | ZNF830 | 0.731203 | 3 | 0 | 3 |
| TBC1D17 | NDUFAF3 | 0.726905 | 3 | 0 | 3 |
| TBC1D17 | GPD1L | 0.70592 | 3 | 0 | 3 |
| TBC1D17 | INTS1 | 0.704235 | 3 | 0 | 3 |
| TBC1D17 | ZNF449 | 0.701301 | 3 | 0 | 3 |
| TBC1D17 | CNST | 0.69854 | 4 | 0 | 3 |
| TBC1D17 | CCDC154 | 0.694788 | 3 | 0 | 3 |
| TBC1D17 | DERL3 | 0.694347 | 3 | 0 | 3 |
| TBC1D17 | NR1H2 | 0.690956 | 8 | 0 | 7 |
| TBC1D17 | CPEB3 | 0.690167 | 4 | 0 | 4 |
| TBC1D17 | DLG2 | 0.689203 | 3 | 0 | 3 |
| TBC1D17 | NFIA | 0.682555 | 4 | 0 | 4 |
| TBC1D17 | ANAPC16 | 0.681705 | 4 | 0 | 4 |
| TBC1D17 | ING4 | 0.680855 | 4 | 0 | 3 |
| TBC1D17 | PCGF2 | 0.674513 | 4 | 0 | 3 |
| TBC1D17 | SKI | 0.674267 | 3 | 0 | 3 |
For details and further investigation, click here
