| Full name: four and a half LIM domains 5 | Alias Symbol: FLJ33049|ACT|dJ393D12.2 | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 9457 | HGNC ID: HGNC:17371 | Ensembl Gene: ENSG00000112214 | OMIM ID: 605126 |
| Drug and gene relationship at DGIdb | |||
Expression of FHL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FHL5 | 9457 | 220170_at | -2.1423 | 0.0407 | |
| GSE20347 | FHL5 | 9457 | 220170_at | -0.0210 | 0.7518 | |
| GSE23400 | FHL5 | 9457 | 220170_at | -0.1727 | 0.0000 | |
| GSE26886 | FHL5 | 9457 | 220170_at | -0.0952 | 0.4752 | |
| GSE29001 | FHL5 | 9457 | 220170_at | -0.2147 | 0.1443 | |
| GSE38129 | FHL5 | 9457 | 220170_at | -0.5536 | 0.0085 | |
| GSE45670 | FHL5 | 9457 | 220170_at | -1.6079 | 0.0000 | |
| GSE53622 | FHL5 | 9457 | 74208 | -2.6033 | 0.0000 | |
| GSE53624 | FHL5 | 9457 | 74208 | -2.2038 | 0.0000 | |
| GSE63941 | FHL5 | 9457 | 1555191_a_at | 0.0956 | 0.4608 | |
| GSE77861 | FHL5 | 9457 | 220170_at | 0.0034 | 0.9801 | |
| GSE97050 | FHL5 | 9457 | A_23_P42358 | -0.3339 | 0.2545 | |
| SRP007169 | FHL5 | 9457 | RNAseq | 0.0089 | 0.9864 | |
| SRP064894 | FHL5 | 9457 | RNAseq | -0.4267 | 0.4586 | |
| SRP133303 | FHL5 | 9457 | RNAseq | -2.3369 | 0.0000 | |
| SRP159526 | FHL5 | 9457 | RNAseq | -1.6371 | 0.0040 | |
| SRP219564 | FHL5 | 9457 | RNAseq | -1.1989 | 0.1404 | |
| TCGA | FHL5 | 9457 | RNAseq | -1.5198 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by FHL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FHL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FHL5 | 9457 | 1 | 3 | 26 | |
| GSE20123 | FHL5 | 9457 | 1 | 2 | 27 | |
| GSE43470 | FHL5 | 9457 | 3 | 2 | 38 | |
| GSE46452 | FHL5 | 9457 | 2 | 11 | 46 | |
| GSE47630 | FHL5 | 9457 | 8 | 6 | 26 | |
| GSE54993 | FHL5 | 9457 | 3 | 2 | 65 | |
| GSE54994 | FHL5 | 9457 | 8 | 8 | 37 | |
| GSE60625 | FHL5 | 9457 | 0 | 1 | 10 | |
| GSE74703 | FHL5 | 9457 | 2 | 2 | 32 | |
| GSE74704 | FHL5 | 9457 | 0 | 0 | 20 | |
| TCGA | FHL5 | 9457 | 5 | 25 | 66 |
Total number of gains: 33; Total number of losses: 62; Total Number of normals: 393.
Somatic mutations of FHL5:
Generating mutation plots.
Highly correlated genes for FHL5:
Showing top 20/1258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FHL5 | CLEC3B | 0.869156 | 3 | 0 | 3 |
| FHL5 | FIBIN | 0.855347 | 3 | 0 | 3 |
| FHL5 | EBF1 | 0.843318 | 5 | 0 | 5 |
| FHL5 | LINC01082 | 0.840383 | 4 | 0 | 4 |
| FHL5 | LRRN4CL | 0.829965 | 5 | 0 | 5 |
| FHL5 | CYP21A2 | 0.813552 | 3 | 0 | 3 |
| FHL5 | LRFN5 | 0.810172 | 4 | 0 | 4 |
| FHL5 | PLCXD3 | 0.806781 | 4 | 0 | 4 |
| FHL5 | SORCS1 | 0.797337 | 4 | 0 | 4 |
| FHL5 | CYP4V2 | 0.793495 | 3 | 0 | 3 |
| FHL5 | XKR4 | 0.793378 | 5 | 0 | 5 |
| FHL5 | ANGPTL1 | 0.791559 | 6 | 0 | 6 |
| FHL5 | RGS7BP | 0.78728 | 6 | 0 | 6 |
| FHL5 | MAMDC2 | 0.783616 | 6 | 0 | 6 |
| FHL5 | FBXL3 | 0.781937 | 3 | 0 | 3 |
| FHL5 | CYYR1 | 0.776943 | 5 | 0 | 5 |
| FHL5 | NR2F1 | 0.774991 | 3 | 0 | 3 |
| FHL5 | KCNAB1 | 0.769236 | 6 | 0 | 6 |
| FHL5 | RBPMS2 | 0.768493 | 5 | 0 | 5 |
| FHL5 | C3orf70 | 0.767356 | 5 | 0 | 5 |
For details and further investigation, click here
