| Full name: chromosome 3 open reading frame 49 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 132200 | HGNC ID: HGNC:25190 | Ensembl Gene: ENSG00000163632 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf49 | 132200 | 1553805_at | 0.0914 | 0.7337 | |
| GSE26886 | C3orf49 | 132200 | 1553805_at | -0.3789 | 0.0004 | |
| GSE45670 | C3orf49 | 132200 | 1553805_at | 0.0559 | 0.4335 | |
| GSE53622 | C3orf49 | 132200 | 13879 | -0.2204 | 0.0006 | |
| GSE53624 | C3orf49 | 132200 | 13879 | -0.2642 | 0.0000 | |
| GSE63941 | C3orf49 | 132200 | 1553805_at | 0.2389 | 0.0715 | |
| GSE77861 | C3orf49 | 132200 | 1553805_at | -0.1257 | 0.2605 | |
| SRP133303 | C3orf49 | 132200 | RNAseq | -0.0111 | 0.9545 | |
| TCGA | C3orf49 | 132200 | RNAseq | -1.7752 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C3orf49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C3orf49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf49 | 132200 | 0 | 18 | 12 | |
| GSE20123 | C3orf49 | 132200 | 0 | 18 | 12 | |
| GSE43470 | C3orf49 | 132200 | 0 | 19 | 24 | |
| GSE46452 | C3orf49 | 132200 | 2 | 17 | 40 | |
| GSE47630 | C3orf49 | 132200 | 1 | 24 | 15 | |
| GSE54993 | C3orf49 | 132200 | 5 | 2 | 63 | |
| GSE54994 | C3orf49 | 132200 | 1 | 33 | 19 | |
| GSE60625 | C3orf49 | 132200 | 3 | 1 | 7 | |
| GSE74703 | C3orf49 | 132200 | 0 | 15 | 21 | |
| GSE74704 | C3orf49 | 132200 | 0 | 12 | 8 | |
| TCGA | C3orf49 | 132200 | 0 | 77 | 19 |
Total number of gains: 12; Total number of losses: 236; Total Number of normals: 240.
Somatic mutations of C3orf49:
Generating mutation plots.
Highly correlated genes for C3orf49:
Showing top 20/28 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf49 | CD5L | 0.6593 | 4 | 0 | 3 |
| C3orf49 | ZNF569 | 0.648658 | 3 | 0 | 3 |
| C3orf49 | CES3 | 0.620875 | 4 | 0 | 4 |
| C3orf49 | RNASE11 | 0.606151 | 3 | 0 | 3 |
| C3orf49 | SKI | 0.605707 | 3 | 0 | 3 |
| C3orf49 | ZC4H2 | 0.601219 | 3 | 0 | 3 |
| C3orf49 | TAT | 0.592632 | 4 | 0 | 4 |
| C3orf49 | SOX6 | 0.585055 | 3 | 0 | 3 |
| C3orf49 | NCAN | 0.581616 | 4 | 0 | 3 |
| C3orf49 | ADAMTSL4 | 0.57902 | 4 | 0 | 3 |
| C3orf49 | SMR3B | 0.578853 | 3 | 0 | 3 |
| C3orf49 | CACNA1G | 0.576828 | 3 | 0 | 3 |
| C3orf49 | ITM2A | 0.572793 | 3 | 0 | 3 |
| C3orf49 | TTLL7-IT1 | 0.562939 | 4 | 0 | 3 |
| C3orf49 | PAX2 | 0.561999 | 4 | 0 | 3 |
| C3orf49 | DEFB118 | 0.560114 | 3 | 0 | 3 |
| C3orf49 | GPR101 | 0.547483 | 4 | 0 | 3 |
| C3orf49 | MYRIP | 0.543354 | 3 | 0 | 3 |
| C3orf49 | MAP3K19 | 0.539231 | 4 | 0 | 3 |
| C3orf49 | OR1F1 | 0.53666 | 5 | 0 | 3 |
For details and further investigation, click here
