| Full name: mitogen-activated protein kinase kinase kinase 19 | Alias Symbol: FLJ23074|RCK | ||
| Type: protein-coding gene | Cytoband: 2q21.3 | ||
| Entrez ID: 80122 | HGNC ID: HGNC:26249 | Ensembl Gene: ENSG00000176601 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MAP3K19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAP3K19 | 80122 | 221180_at | -0.0244 | 0.9479 | |
| GSE20347 | MAP3K19 | 80122 | 221180_at | 0.0361 | 0.7318 | |
| GSE23400 | MAP3K19 | 80122 | 221180_at | -0.1119 | 0.0081 | |
| GSE26886 | MAP3K19 | 80122 | 221180_at | -0.2740 | 0.0116 | |
| GSE29001 | MAP3K19 | 80122 | 221180_at | -0.2639 | 0.1655 | |
| GSE38129 | MAP3K19 | 80122 | 221180_at | -0.1527 | 0.1779 | |
| GSE45670 | MAP3K19 | 80122 | 221180_at | -0.0739 | 0.4261 | |
| GSE53622 | MAP3K19 | 80122 | 114355 | -0.1666 | 0.2159 | |
| GSE53624 | MAP3K19 | 80122 | 114355 | -0.3633 | 0.0002 | |
| GSE63941 | MAP3K19 | 80122 | 221180_at | 0.2422 | 0.1473 | |
| GSE77861 | MAP3K19 | 80122 | 221180_at | -0.1535 | 0.2267 | |
| SRP133303 | MAP3K19 | 80122 | RNAseq | 0.6920 | 0.0610 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAP3K19 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MAP3K19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAP3K19 | 80122 | 2 | 4 | 24 | |
| GSE20123 | MAP3K19 | 80122 | 2 | 4 | 24 | |
| GSE43470 | MAP3K19 | 80122 | 1 | 1 | 41 | |
| GSE46452 | MAP3K19 | 80122 | 1 | 4 | 54 | |
| GSE47630 | MAP3K19 | 80122 | 5 | 2 | 33 | |
| GSE54993 | MAP3K19 | 80122 | 0 | 6 | 64 | |
| GSE54994 | MAP3K19 | 80122 | 9 | 0 | 44 | |
| GSE60625 | MAP3K19 | 80122 | 0 | 3 | 8 | |
| GSE74703 | MAP3K19 | 80122 | 1 | 1 | 34 | |
| GSE74704 | MAP3K19 | 80122 | 1 | 1 | 18 | |
| TCGA | MAP3K19 | 80122 | 22 | 10 | 64 |
Total number of gains: 44; Total number of losses: 36; Total Number of normals: 408.
Somatic mutations of MAP3K19:
Generating mutation plots.
Highly correlated genes for MAP3K19:
Showing top 20/943 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAP3K19 | CYP3A4 | 0.770852 | 3 | 0 | 3 |
| MAP3K19 | AMN | 0.76834 | 3 | 0 | 3 |
| MAP3K19 | NAAA | 0.760147 | 3 | 0 | 3 |
| MAP3K19 | CLCF1 | 0.725403 | 3 | 0 | 3 |
| MAP3K19 | MUC2 | 0.71684 | 5 | 0 | 5 |
| MAP3K19 | PAPPA2 | 0.715808 | 6 | 0 | 5 |
| MAP3K19 | CNTNAP1 | 0.710764 | 3 | 0 | 3 |
| MAP3K19 | PSG1 | 0.708369 | 7 | 0 | 7 |
| MAP3K19 | IGHMBP2 | 0.707837 | 3 | 0 | 3 |
| MAP3K19 | SMCP | 0.706235 | 7 | 0 | 7 |
| MAP3K19 | PDYN | 0.704317 | 5 | 0 | 5 |
| MAP3K19 | KIF5A | 0.704231 | 6 | 0 | 6 |
| MAP3K19 | SCN10A | 0.704082 | 7 | 0 | 7 |
| MAP3K19 | EPOR | 0.703918 | 7 | 0 | 7 |
| MAP3K19 | KCNJ10 | 0.702228 | 4 | 0 | 3 |
| MAP3K19 | RGR | 0.701326 | 4 | 0 | 4 |
| MAP3K19 | TMEM212 | 0.699451 | 3 | 0 | 3 |
| MAP3K19 | CETN1 | 0.699322 | 4 | 0 | 4 |
| MAP3K19 | CGA | 0.692279 | 5 | 0 | 4 |
| MAP3K19 | SLC10A1 | 0.691957 | 6 | 0 | 5 |
For details and further investigation, click here
