| Full name: ribonuclease A family member 11 (inactive) | Alias Symbol: RAJ1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 122651 | HGNC ID: HGNC:19269 | Ensembl Gene: ENSG00000173464 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNASE11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNASE11 | 122651 | 231603_at | -0.2010 | 0.2672 | |
| GSE26886 | RNASE11 | 122651 | 231603_at | -0.1122 | 0.1927 | |
| GSE45670 | RNASE11 | 122651 | 231603_at | 0.0653 | 0.4640 | |
| GSE63941 | RNASE11 | 122651 | 231603_at | -0.0474 | 0.6523 | |
| GSE77861 | RNASE11 | 122651 | 231603_at | -0.0922 | 0.2170 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNASE11 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RNASE11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNASE11 | 122651 | 9 | 3 | 18 | |
| GSE20123 | RNASE11 | 122651 | 8 | 3 | 19 | |
| GSE43470 | RNASE11 | 122651 | 7 | 1 | 35 | |
| GSE46452 | RNASE11 | 122651 | 19 | 2 | 38 | |
| GSE47630 | RNASE11 | 122651 | 10 | 10 | 20 | |
| GSE54993 | RNASE11 | 122651 | 3 | 11 | 56 | |
| GSE54994 | RNASE11 | 122651 | 18 | 5 | 30 | |
| GSE60625 | RNASE11 | 122651 | 0 | 2 | 9 | |
| GSE74703 | RNASE11 | 122651 | 6 | 1 | 29 | |
| GSE74704 | RNASE11 | 122651 | 4 | 2 | 14 | |
| TCGA | RNASE11 | 122651 | 28 | 17 | 51 |
Total number of gains: 112; Total number of losses: 57; Total Number of normals: 319.
Somatic mutations of RNASE11:
Generating mutation plots.
Highly correlated genes for RNASE11:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNASE11 | CD1C | 0.669819 | 3 | 0 | 3 |
| RNASE11 | SCARF1 | 0.629314 | 3 | 0 | 3 |
| RNASE11 | C1QTNF7 | 0.625755 | 3 | 0 | 3 |
| RNASE11 | TIRAP | 0.617783 | 3 | 0 | 3 |
| RNASE11 | CD300LG | 0.607245 | 3 | 0 | 3 |
| RNASE11 | LCN8 | 0.606275 | 3 | 0 | 3 |
| RNASE11 | C3orf49 | 0.606151 | 3 | 0 | 3 |
| RNASE11 | ZNF554 | 0.59945 | 3 | 0 | 3 |
| RNASE11 | CSPG5 | 0.589271 | 4 | 0 | 4 |
| RNASE11 | PCA3 | 0.587304 | 4 | 0 | 3 |
| RNASE11 | ANO2 | 0.577631 | 3 | 0 | 3 |
| RNASE11 | SH2D1B | 0.576028 | 4 | 0 | 3 |
| RNASE11 | OR6B1 | 0.562548 | 4 | 0 | 4 |
| RNASE11 | DNAI1 | 0.55507 | 3 | 0 | 3 |
| RNASE11 | ZNF460 | 0.534586 | 4 | 0 | 3 |
| RNASE11 | SIGLEC6 | 0.531268 | 5 | 0 | 3 |
| RNASE11 | TMEM132B | 0.52962 | 4 | 0 | 3 |
| RNASE11 | GPR15 | 0.525538 | 4 | 0 | 3 |
| RNASE11 | KIF12 | 0.522227 | 4 | 0 | 3 |
| RNASE11 | MMEL1 | 0.520498 | 4 | 0 | 3 |
For details and further investigation, click here
