| Full name: forkhead box P3 | Alias Symbol: JM2|XPID|AIID|PIDX|DIETER|SCURFIN | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 50943 | HGNC ID: HGNC:6106 | Ensembl Gene: ENSG00000049768 | OMIM ID: 300292 |
| Drug and gene relationship at DGIdb | |||
FOXP3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05321 | Inflammatory bowel disease (IBD) |
Expression of FOXP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXP3 | 50943 | 224211_at | 0.0033 | 0.9948 | |
| GSE20347 | FOXP3 | 50943 | 221334_s_at | 0.0334 | 0.7283 | |
| GSE23400 | FOXP3 | 50943 | 221333_at | -0.1876 | 0.0000 | |
| GSE26886 | FOXP3 | 50943 | 221334_s_at | 0.0992 | 0.3473 | |
| GSE29001 | FOXP3 | 50943 | 221334_s_at | -0.1693 | 0.1815 | |
| GSE38129 | FOXP3 | 50943 | 221334_s_at | -0.1052 | 0.2529 | |
| GSE45670 | FOXP3 | 50943 | 221334_s_at | -0.0181 | 0.8698 | |
| GSE53622 | FOXP3 | 50943 | 48632 | 0.7330 | 0.0000 | |
| GSE53624 | FOXP3 | 50943 | 48632 | 0.2465 | 0.0234 | |
| GSE63941 | FOXP3 | 50943 | 221334_s_at | 0.0469 | 0.7485 | |
| GSE77861 | FOXP3 | 50943 | 221334_s_at | -0.0842 | 0.2664 | |
| GSE97050 | FOXP3 | 50943 | A_33_P3398251 | 1.2342 | 0.1298 | |
| SRP064894 | FOXP3 | 50943 | RNAseq | 1.6876 | 0.0000 | |
| SRP133303 | FOXP3 | 50943 | RNAseq | 1.2271 | 0.0000 | |
| SRP159526 | FOXP3 | 50943 | RNAseq | 0.4179 | 0.4259 | |
| SRP193095 | FOXP3 | 50943 | RNAseq | 0.8803 | 0.0006 | |
| SRP219564 | FOXP3 | 50943 | RNAseq | 2.2722 | 0.0006 | |
| TCGA | FOXP3 | 50943 | RNAseq | 1.5068 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FOXP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXP3:
No record found for this gene.
Somatic mutations of FOXP3:
Generating mutation plots.
Highly correlated genes for FOXP3:
Showing top 20/761 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXP3 | CD3E | 0.780099 | 3 | 0 | 3 |
| FOXP3 | HOXB-AS3 | 0.725644 | 3 | 0 | 3 |
| FOXP3 | C8B | 0.70846 | 3 | 0 | 3 |
| FOXP3 | RUNX2 | 0.70622 | 7 | 0 | 6 |
| FOXP3 | TCL6 | 0.695811 | 4 | 0 | 4 |
| FOXP3 | ZC3H3 | 0.689611 | 3 | 0 | 3 |
| FOXP3 | OR10H3 | 0.689408 | 4 | 0 | 4 |
| FOXP3 | ART1 | 0.685831 | 4 | 0 | 4 |
| FOXP3 | ETS1 | 0.685026 | 3 | 0 | 3 |
| FOXP3 | C10orf95 | 0.681974 | 5 | 0 | 4 |
| FOXP3 | CTLA4 | 0.681588 | 5 | 0 | 5 |
| FOXP3 | SIGLEC6 | 0.680665 | 5 | 0 | 5 |
| FOXP3 | MAS1 | 0.678784 | 5 | 0 | 4 |
| FOXP3 | IL2RG | 0.675328 | 4 | 0 | 3 |
| FOXP3 | CAMK2N2 | 0.674329 | 3 | 0 | 3 |
| FOXP3 | LENEP | 0.674209 | 4 | 0 | 4 |
| FOXP3 | C16orf71 | 0.674201 | 4 | 0 | 4 |
| FOXP3 | CCDC63 | 0.672825 | 4 | 0 | 4 |
| FOXP3 | LMF2 | 0.670673 | 3 | 0 | 3 |
| FOXP3 | CPA2 | 0.668216 | 3 | 0 | 3 |
For details and further investigation, click here
