| Full name: complement component 5a receptor 2 | Alias Symbol: C5L2 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 27202 | HGNC ID: HGNC:4527 | Ensembl Gene: ENSG00000134830 | OMIM ID: 609949 |
| Drug and gene relationship at DGIdb | |||
Expression of C5AR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C5AR2 | 27202 | 221149_at | 0.0883 | 0.7396 | |
| GSE20347 | C5AR2 | 27202 | 221149_at | -0.0703 | 0.1886 | |
| GSE23400 | C5AR2 | 27202 | 221149_at | -0.0962 | 0.0006 | |
| GSE26886 | C5AR2 | 27202 | 221149_at | 0.0259 | 0.8432 | |
| GSE29001 | C5AR2 | 27202 | 221149_at | -0.0502 | 0.7345 | |
| GSE38129 | C5AR2 | 27202 | 221149_at | -0.1449 | 0.0467 | |
| GSE45670 | C5AR2 | 27202 | 221149_at | 0.2546 | 0.0220 | |
| GSE53622 | C5AR2 | 27202 | 19119 | 0.0181 | 0.8795 | |
| GSE53624 | C5AR2 | 27202 | 19119 | -0.0017 | 0.9879 | |
| GSE63941 | C5AR2 | 27202 | 221149_at | 0.0036 | 0.9842 | |
| GSE77861 | C5AR2 | 27202 | 221149_at | -0.1297 | 0.1679 | |
| SRP007169 | C5AR2 | 27202 | RNAseq | -0.2835 | 0.5661 | |
| SRP008496 | C5AR2 | 27202 | RNAseq | -0.0822 | 0.8358 | |
| SRP064894 | C5AR2 | 27202 | RNAseq | -0.3417 | 0.2381 | |
| SRP133303 | C5AR2 | 27202 | RNAseq | -0.2852 | 0.0440 | |
| SRP159526 | C5AR2 | 27202 | RNAseq | -1.0146 | 0.0183 | |
| SRP193095 | C5AR2 | 27202 | RNAseq | -0.1095 | 0.4802 | |
| SRP219564 | C5AR2 | 27202 | RNAseq | 1.2817 | 0.0685 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C5AR2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of C5AR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C5AR2 | 27202 | 4 | 4 | 22 | |
| GSE20123 | C5AR2 | 27202 | 4 | 3 | 23 | |
| GSE43470 | C5AR2 | 27202 | 3 | 10 | 30 | |
| GSE46452 | C5AR2 | 27202 | 45 | 1 | 13 | |
| GSE47630 | C5AR2 | 27202 | 8 | 7 | 25 | |
| GSE54993 | C5AR2 | 27202 | 17 | 4 | 49 | |
| GSE54994 | C5AR2 | 27202 | 4 | 14 | 35 | |
| GSE60625 | C5AR2 | 27202 | 9 | 0 | 2 | |
| GSE74703 | C5AR2 | 27202 | 3 | 7 | 26 | |
| GSE74704 | C5AR2 | 27202 | 4 | 1 | 15 | |
| TCGA | C5AR2 | 27202 | 14 | 18 | 64 |
Total number of gains: 115; Total number of losses: 69; Total Number of normals: 304.
Somatic mutations of C5AR2:
Generating mutation plots.
Highly correlated genes for C5AR2:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C5AR2 | TDRD1 | 0.704667 | 3 | 0 | 3 |
| C5AR2 | LINC00652 | 0.70051 | 3 | 0 | 3 |
| C5AR2 | SPINK6 | 0.696132 | 3 | 0 | 3 |
| C5AR2 | MASP2 | 0.695491 | 4 | 0 | 4 |
| C5AR2 | C16orf70 | 0.694083 | 3 | 0 | 3 |
| C5AR2 | LGR5 | 0.690758 | 3 | 0 | 3 |
| C5AR2 | DAB1 | 0.668711 | 5 | 0 | 5 |
| C5AR2 | KSR1 | 0.668565 | 4 | 0 | 3 |
| C5AR2 | LRTM1 | 0.667093 | 6 | 0 | 6 |
| C5AR2 | SAMD4B | 0.66521 | 3 | 0 | 3 |
| C5AR2 | C8B | 0.66454 | 5 | 0 | 4 |
| C5AR2 | NTNG1 | 0.659671 | 3 | 0 | 3 |
| C5AR2 | GLP1R | 0.659602 | 4 | 0 | 3 |
| C5AR2 | CPA2 | 0.658165 | 3 | 0 | 3 |
| C5AR2 | NEUROD2 | 0.656746 | 4 | 0 | 3 |
| C5AR2 | RNF17 | 0.654435 | 4 | 0 | 4 |
| C5AR2 | IFNA4 | 0.650127 | 4 | 0 | 3 |
| C5AR2 | NR6A1 | 0.649776 | 4 | 0 | 4 |
| C5AR2 | TUBB4A | 0.649744 | 4 | 0 | 4 |
| C5AR2 | HTR3B | 0.648994 | 5 | 0 | 5 |
For details and further investigation, click here
