| Full name: calcium voltage-gated channel auxiliary subunit gamma 2 | Alias Symbol: stargazin|MGC138502|MGC138504 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 10369 | HGNC ID: HGNC:1406 | Ensembl Gene: ENSG00000166862 | OMIM ID: 602911 |
| Drug and gene relationship at DGIdb | |||
CACNG2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04261 | Adrenergic signaling in cardiomyocytes | |
| hsa04921 | Oxytocin signaling pathway |
Expression of CACNG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNG2 | 10369 | 214495_at | -0.1141 | 0.7107 | |
| GSE20347 | CACNG2 | 10369 | 214495_at | 0.1157 | 0.1416 | |
| GSE23400 | CACNG2 | 10369 | 214495_at | -0.0663 | 0.0260 | |
| GSE26886 | CACNG2 | 10369 | 214495_at | 0.4814 | 0.0003 | |
| GSE29001 | CACNG2 | 10369 | 214495_at | -0.1502 | 0.2650 | |
| GSE38129 | CACNG2 | 10369 | 214495_at | -0.0384 | 0.6702 | |
| GSE45670 | CACNG2 | 10369 | 244099_at | 0.1694 | 0.0689 | |
| GSE53622 | CACNG2 | 10369 | 11257 | -0.2001 | 0.1539 | |
| GSE53624 | CACNG2 | 10369 | 11257 | -0.7264 | 0.0000 | |
| GSE63941 | CACNG2 | 10369 | 214495_at | 0.1231 | 0.3498 | |
| GSE77861 | CACNG2 | 10369 | 214495_at | -0.0869 | 0.3408 | |
| SRP133303 | CACNG2 | 10369 | RNAseq | -0.0535 | 0.8591 | |
| TCGA | CACNG2 | 10369 | RNAseq | 0.7747 | 0.7252 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CACNG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACNG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNG2 | 10369 | 6 | 6 | 18 | |
| GSE20123 | CACNG2 | 10369 | 6 | 5 | 19 | |
| GSE43470 | CACNG2 | 10369 | 4 | 6 | 33 | |
| GSE46452 | CACNG2 | 10369 | 31 | 1 | 27 | |
| GSE47630 | CACNG2 | 10369 | 8 | 5 | 27 | |
| GSE54993 | CACNG2 | 10369 | 3 | 6 | 61 | |
| GSE54994 | CACNG2 | 10369 | 9 | 9 | 35 | |
| GSE60625 | CACNG2 | 10369 | 5 | 0 | 6 | |
| GSE74703 | CACNG2 | 10369 | 4 | 4 | 28 | |
| GSE74704 | CACNG2 | 10369 | 3 | 2 | 15 | |
| TCGA | CACNG2 | 10369 | 27 | 16 | 53 |
Total number of gains: 106; Total number of losses: 60; Total Number of normals: 322.
Somatic mutations of CACNG2:
Generating mutation plots.
Highly correlated genes for CACNG2:
Showing top 20/665 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNG2 | MYL1 | 0.754634 | 3 | 0 | 3 |
| CACNG2 | RECK | 0.705585 | 3 | 0 | 3 |
| CACNG2 | FRMPD4 | 0.705325 | 4 | 0 | 3 |
| CACNG2 | TMEM8B | 0.704814 | 3 | 0 | 3 |
| CACNG2 | SLC10A1 | 0.693849 | 4 | 0 | 4 |
| CACNG2 | GRIK2 | 0.689304 | 3 | 0 | 3 |
| CACNG2 | LINC00304 | 0.677212 | 3 | 0 | 3 |
| CACNG2 | BPY2 | 0.67397 | 4 | 0 | 3 |
| CACNG2 | TFAP2A-AS1 | 0.672744 | 4 | 0 | 4 |
| CACNG2 | SLC10A2 | 0.670355 | 4 | 0 | 4 |
| CACNG2 | TDRD1 | 0.668268 | 5 | 0 | 4 |
| CACNG2 | AFP | 0.667701 | 4 | 0 | 4 |
| CACNG2 | MASP2 | 0.664848 | 4 | 0 | 4 |
| CACNG2 | OR2H1 | 0.66438 | 4 | 0 | 4 |
| CACNG2 | CGA | 0.66337 | 5 | 0 | 4 |
| CACNG2 | CYP3A4 | 0.6621 | 4 | 0 | 4 |
| CACNG2 | ZBED3-AS1 | 0.661907 | 3 | 0 | 3 |
| CACNG2 | PDYN | 0.659538 | 4 | 0 | 4 |
| CACNG2 | CABP1 | 0.659295 | 4 | 0 | 4 |
| CACNG2 | NPY | 0.658564 | 3 | 0 | 3 |
For details and further investigation, click here
