| Full name: reversion inducing cysteine rich protein with kazal motifs | Alias Symbol: hRECK | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 8434 | HGNC ID: HGNC:11345 | Ensembl Gene: ENSG00000122707 | OMIM ID: 605227 |
| Drug and gene relationship at DGIdb | |||
Expression of RECK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RECK | 8434 | 205407_at | -1.9485 | 0.0648 | |
| GSE20347 | RECK | 8434 | 216153_x_at | 0.2539 | 0.1714 | |
| GSE23400 | RECK | 8434 | 216153_x_at | 0.0696 | 0.1218 | |
| GSE26886 | RECK | 8434 | 216153_x_at | -0.1577 | 0.1561 | |
| GSE29001 | RECK | 8434 | 216153_x_at | -0.0285 | 0.9147 | |
| GSE38129 | RECK | 8434 | 216153_x_at | -0.1028 | 0.7218 | |
| GSE45670 | RECK | 8434 | 216153_x_at | 0.0468 | 0.6179 | |
| GSE53622 | RECK | 8434 | 18732 | -1.0353 | 0.0000 | |
| GSE53624 | RECK | 8434 | 92791 | -1.1443 | 0.0000 | |
| GSE63941 | RECK | 8434 | 216153_x_at | 1.0046 | 0.0000 | |
| GSE77861 | RECK | 8434 | 216153_x_at | -0.0258 | 0.9049 | |
| GSE97050 | RECK | 8434 | A_33_P3269899 | -1.0047 | 0.0555 | |
| SRP007169 | RECK | 8434 | RNAseq | 1.3878 | 0.0549 | |
| SRP008496 | RECK | 8434 | RNAseq | 2.6942 | 0.0000 | |
| SRP064894 | RECK | 8434 | RNAseq | -0.2745 | 0.3795 | |
| SRP133303 | RECK | 8434 | RNAseq | -0.6140 | 0.0074 | |
| SRP159526 | RECK | 8434 | RNAseq | -0.5691 | 0.0345 | |
| SRP193095 | RECK | 8434 | RNAseq | 0.5093 | 0.0193 | |
| SRP219564 | RECK | 8434 | RNAseq | 0.3985 | 0.5576 | |
| TCGA | RECK | 8434 | RNAseq | -0.7238 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by RECK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RECK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RECK | 8434 | 3 | 12 | 15 | |
| GSE20123 | RECK | 8434 | 3 | 12 | 15 | |
| GSE43470 | RECK | 8434 | 3 | 10 | 30 | |
| GSE46452 | RECK | 8434 | 6 | 15 | 38 | |
| GSE47630 | RECK | 8434 | 1 | 20 | 19 | |
| GSE54993 | RECK | 8434 | 6 | 0 | 64 | |
| GSE54994 | RECK | 8434 | 5 | 12 | 36 | |
| GSE60625 | RECK | 8434 | 0 | 0 | 11 | |
| GSE74703 | RECK | 8434 | 2 | 7 | 27 | |
| GSE74704 | RECK | 8434 | 0 | 10 | 10 | |
| TCGA | RECK | 8434 | 15 | 44 | 37 |
Total number of gains: 44; Total number of losses: 142; Total Number of normals: 302.
Somatic mutations of RECK:
Generating mutation plots.
Highly correlated genes for RECK:
Showing top 20/530 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RECK | C1QTNF7 | 0.845154 | 4 | 0 | 4 |
| RECK | ZBTB16 | 0.833675 | 3 | 0 | 3 |
| RECK | TCEAL6 | 0.826481 | 3 | 0 | 3 |
| RECK | CLEC3B | 0.813795 | 3 | 0 | 3 |
| RECK | SPTLC3 | 0.800312 | 3 | 0 | 3 |
| RECK | NR2F1 | 0.795658 | 3 | 0 | 3 |
| RECK | SORCS1 | 0.793138 | 4 | 0 | 4 |
| RECK | PLCXD3 | 0.789776 | 3 | 0 | 3 |
| RECK | TNFSF12 | 0.786904 | 4 | 0 | 4 |
| RECK | TCEAL5 | 0.782105 | 3 | 0 | 3 |
| RECK | RERGL | 0.774822 | 4 | 0 | 4 |
| RECK | SMTNL2 | 0.772636 | 4 | 0 | 4 |
| RECK | CYP21A2 | 0.766798 | 3 | 0 | 3 |
| RECK | CEP57 | 0.766349 | 3 | 0 | 3 |
| RECK | PRPS1L1 | 0.762129 | 4 | 0 | 4 |
| RECK | XKR4 | 0.761374 | 4 | 0 | 4 |
| RECK | TLE2 | 0.760209 | 3 | 0 | 3 |
| RECK | CHD2 | 0.759821 | 4 | 0 | 4 |
| RECK | MYOC | 0.755764 | 4 | 0 | 4 |
| RECK | FRAS1 | 0.754737 | 5 | 0 | 5 |
For details and further investigation, click here
