| Full name: neuropeptide FF receptor 1 | Alias Symbol: OT7T022|NPFF1R1 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 64106 | HGNC ID: HGNC:17425 | Ensembl Gene: ENSG00000148734 | OMIM ID: 607448 |
| Drug and gene relationship at DGIdb | |||
Expression of NPFFR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPFFR1 | 64106 | 221387_at | -0.0592 | 0.8118 | |
| GSE20347 | NPFFR1 | 64106 | 221387_at | 0.0010 | 0.9920 | |
| GSE23400 | NPFFR1 | 64106 | 221387_at | -0.1032 | 0.0059 | |
| GSE26886 | NPFFR1 | 64106 | 221387_at | 0.5660 | 0.0002 | |
| GSE29001 | NPFFR1 | 64106 | 221387_at | 0.0370 | 0.8665 | |
| GSE38129 | NPFFR1 | 64106 | 221387_at | -0.0518 | 0.6917 | |
| GSE45670 | NPFFR1 | 64106 | 221387_at | 0.1444 | 0.0897 | |
| GSE53622 | NPFFR1 | 64106 | 99291 | -0.1518 | 0.1358 | |
| GSE53624 | NPFFR1 | 64106 | 99291 | 0.0202 | 0.8230 | |
| GSE63941 | NPFFR1 | 64106 | 221387_at | 0.1951 | 0.1789 | |
| GSE77861 | NPFFR1 | 64106 | 221387_at | 0.0900 | 0.6282 | |
| GSE97050 | NPFFR1 | 64106 | A_23_P1452 | -0.0070 | 0.9770 | |
| SRP007169 | NPFFR1 | 64106 | RNAseq | 1.8280 | 0.0397 | |
| SRP064894 | NPFFR1 | 64106 | RNAseq | 0.3041 | 0.2435 | |
| SRP133303 | NPFFR1 | 64106 | RNAseq | 0.1429 | 0.2652 | |
| SRP159526 | NPFFR1 | 64106 | RNAseq | -0.3430 | 0.5209 | |
| SRP193095 | NPFFR1 | 64106 | RNAseq | 0.2031 | 0.1596 | |
| SRP219564 | NPFFR1 | 64106 | RNAseq | 0.8135 | 0.2269 | |
| TCGA | NPFFR1 | 64106 | RNAseq | 1.5959 | 0.0646 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NPFFR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPFFR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPFFR1 | 64106 | 2 | 4 | 24 | |
| GSE20123 | NPFFR1 | 64106 | 2 | 3 | 25 | |
| GSE43470 | NPFFR1 | 64106 | 1 | 7 | 35 | |
| GSE46452 | NPFFR1 | 64106 | 0 | 11 | 48 | |
| GSE47630 | NPFFR1 | 64106 | 2 | 14 | 24 | |
| GSE54993 | NPFFR1 | 64106 | 7 | 0 | 63 | |
| GSE54994 | NPFFR1 | 64106 | 2 | 12 | 39 | |
| GSE60625 | NPFFR1 | 64106 | 0 | 0 | 11 | |
| GSE74703 | NPFFR1 | 64106 | 1 | 4 | 31 | |
| GSE74704 | NPFFR1 | 64106 | 1 | 1 | 18 | |
| TCGA | NPFFR1 | 64106 | 9 | 23 | 64 |
Total number of gains: 27; Total number of losses: 79; Total Number of normals: 382.
Somatic mutations of NPFFR1:
Generating mutation plots.
Highly correlated genes for NPFFR1:
Showing top 20/640 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPFFR1 | FRMD8 | 0.770628 | 3 | 0 | 3 |
| NPFFR1 | BAGE | 0.767377 | 3 | 0 | 3 |
| NPFFR1 | AMBRA1 | 0.757683 | 4 | 0 | 3 |
| NPFFR1 | STAT2 | 0.756326 | 5 | 0 | 5 |
| NPFFR1 | CCIN | 0.745732 | 4 | 0 | 4 |
| NPFFR1 | PTPN2 | 0.738765 | 3 | 0 | 3 |
| NPFFR1 | LIPF | 0.733001 | 4 | 0 | 3 |
| NPFFR1 | MSI1 | 0.732761 | 5 | 0 | 5 |
| NPFFR1 | IRF7 | 0.730582 | 3 | 0 | 3 |
| NPFFR1 | MXD3 | 0.727627 | 3 | 0 | 3 |
| NPFFR1 | C19orf54 | 0.725886 | 3 | 0 | 3 |
| NPFFR1 | A4GALT | 0.722228 | 4 | 0 | 4 |
| NPFFR1 | TRMT61A | 0.720455 | 4 | 0 | 3 |
| NPFFR1 | DZIP1L | 0.719008 | 4 | 0 | 4 |
| NPFFR1 | OR1A1 | 0.717483 | 4 | 0 | 4 |
| NPFFR1 | CACNA1B | 0.71143 | 4 | 0 | 3 |
| NPFFR1 | PRSS12 | 0.710384 | 3 | 0 | 3 |
| NPFFR1 | SAMD1 | 0.70882 | 3 | 0 | 3 |
| NPFFR1 | C11orf16 | 0.70858 | 4 | 0 | 4 |
| NPFFR1 | KLHL31 | 0.707028 | 3 | 0 | 3 |
For details and further investigation, click here
