| Full name: CAS1 domain containing 1 | Alias Symbol: FLJ21213|FLJ21879|C7orf12 | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 64921 | HGNC ID: HGNC:16014 | Ensembl Gene: ENSG00000127995 | OMIM ID: 611686 |
| Drug and gene relationship at DGIdb | |||
Expression of CASD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CASD1 | 64921 | 219342_at | -0.0251 | 0.9753 | |
| GSE20347 | CASD1 | 64921 | 219342_at | 0.5500 | 0.0481 | |
| GSE23400 | CASD1 | 64921 | 219342_at | 0.1343 | 0.0522 | |
| GSE26886 | CASD1 | 64921 | 219342_at | -0.4031 | 0.2705 | |
| GSE29001 | CASD1 | 64921 | 219342_at | 0.5133 | 0.0993 | |
| GSE38129 | CASD1 | 64921 | 219342_at | 0.3156 | 0.1099 | |
| GSE45670 | CASD1 | 64921 | 219342_at | -0.2040 | 0.4733 | |
| GSE53622 | CASD1 | 64921 | 84537 | 0.2564 | 0.0296 | |
| GSE53624 | CASD1 | 64921 | 84537 | 0.2025 | 0.0324 | |
| GSE63941 | CASD1 | 64921 | 219342_at | -0.9445 | 0.2135 | |
| GSE77861 | CASD1 | 64921 | 219342_at | 0.4838 | 0.1629 | |
| GSE97050 | CASD1 | 64921 | A_33_P3231120 | -0.1200 | 0.5932 | |
| SRP007169 | CASD1 | 64921 | RNAseq | 0.5943 | 0.1159 | |
| SRP008496 | CASD1 | 64921 | RNAseq | 1.0375 | 0.0038 | |
| SRP064894 | CASD1 | 64921 | RNAseq | 0.2556 | 0.2346 | |
| SRP133303 | CASD1 | 64921 | RNAseq | 0.4676 | 0.0234 | |
| SRP159526 | CASD1 | 64921 | RNAseq | -0.0665 | 0.7418 | |
| SRP193095 | CASD1 | 64921 | RNAseq | 0.5377 | 0.0004 | |
| SRP219564 | CASD1 | 64921 | RNAseq | 0.4965 | 0.2344 | |
| TCGA | CASD1 | 64921 | RNAseq | -0.0355 | 0.5875 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CASD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CASD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CASD1 | 64921 | 13 | 0 | 17 | |
| GSE20123 | CASD1 | 64921 | 13 | 0 | 17 | |
| GSE43470 | CASD1 | 64921 | 7 | 3 | 33 | |
| GSE46452 | CASD1 | 64921 | 12 | 0 | 47 | |
| GSE47630 | CASD1 | 64921 | 8 | 2 | 30 | |
| GSE54993 | CASD1 | 64921 | 1 | 9 | 60 | |
| GSE54994 | CASD1 | 64921 | 16 | 2 | 35 | |
| GSE60625 | CASD1 | 64921 | 0 | 5 | 6 | |
| GSE74703 | CASD1 | 64921 | 6 | 2 | 28 | |
| GSE74704 | CASD1 | 64921 | 9 | 0 | 11 | |
| TCGA | CASD1 | 64921 | 56 | 4 | 36 |
Total number of gains: 141; Total number of losses: 27; Total Number of normals: 320.
Somatic mutations of CASD1:
Generating mutation plots.
Highly correlated genes for CASD1:
Showing top 20/213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CASD1 | DNAJC8 | 0.688903 | 4 | 0 | 3 |
| CASD1 | ZSWIM5 | 0.652095 | 3 | 0 | 3 |
| CASD1 | KAT7 | 0.646479 | 3 | 0 | 3 |
| CASD1 | CD99L2 | 0.638302 | 4 | 0 | 4 |
| CASD1 | ZNF512 | 0.613868 | 5 | 0 | 4 |
| CASD1 | GIGYF2 | 0.611886 | 3 | 0 | 3 |
| CASD1 | SNAPC5 | 0.607919 | 4 | 0 | 3 |
| CASD1 | TRAM2-AS1 | 0.605792 | 5 | 0 | 4 |
| CASD1 | KIAA1324L | 0.602252 | 5 | 0 | 4 |
| CASD1 | CDC42EP3 | 0.599832 | 7 | 0 | 5 |
| CASD1 | HECTD2 | 0.599779 | 4 | 0 | 3 |
| CASD1 | ZMYM4 | 0.597302 | 9 | 0 | 8 |
| CASD1 | ATP2B4 | 0.594072 | 4 | 0 | 3 |
| CASD1 | NPTX2 | 0.592076 | 8 | 0 | 4 |
| CASD1 | PKD2 | 0.591204 | 9 | 0 | 7 |
| CASD1 | BMPR1B | 0.590754 | 4 | 0 | 3 |
| CASD1 | UBB | 0.586184 | 6 | 0 | 5 |
| CASD1 | HSF2 | 0.585553 | 8 | 0 | 5 |
| CASD1 | SGCE | 0.585361 | 11 | 0 | 8 |
| CASD1 | ARL3 | 0.584308 | 7 | 0 | 4 |
For details and further investigation, click here
