| Full name: DnaJ heat shock protein family (Hsp40) member C8 | Alias Symbol: SPF31 | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 22826 | HGNC ID: HGNC:15470 | Ensembl Gene: ENSG00000126698 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DNAJC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC8 | 22826 | 205545_x_at | -0.0163 | 0.9703 | |
| GSE20347 | DNAJC8 | 22826 | 205545_x_at | 0.1874 | 0.0380 | |
| GSE23400 | DNAJC8 | 22826 | 205545_x_at | 0.2147 | 0.0000 | |
| GSE26886 | DNAJC8 | 22826 | 205545_x_at | 0.1611 | 0.4003 | |
| GSE29001 | DNAJC8 | 22826 | 205545_x_at | 0.2303 | 0.4677 | |
| GSE38129 | DNAJC8 | 22826 | 205545_x_at | 0.1377 | 0.1985 | |
| GSE45670 | DNAJC8 | 22826 | 205545_x_at | 0.1529 | 0.2583 | |
| GSE53622 | DNAJC8 | 22826 | 49449 | -0.4185 | 0.0034 | |
| GSE53624 | DNAJC8 | 22826 | 37636 | -0.0035 | 0.9785 | |
| GSE63941 | DNAJC8 | 22826 | 205545_x_at | -0.3056 | 0.3304 | |
| GSE77861 | DNAJC8 | 22826 | 205545_x_at | 0.1411 | 0.4289 | |
| GSE97050 | DNAJC8 | 22826 | A_23_P46455 | -0.2303 | 0.4052 | |
| SRP007169 | DNAJC8 | 22826 | RNAseq | -0.0217 | 0.9515 | |
| SRP008496 | DNAJC8 | 22826 | RNAseq | -0.1675 | 0.4231 | |
| SRP064894 | DNAJC8 | 22826 | RNAseq | 0.3493 | 0.0062 | |
| SRP133303 | DNAJC8 | 22826 | RNAseq | 0.3931 | 0.0046 | |
| SRP159526 | DNAJC8 | 22826 | RNAseq | 0.0220 | 0.9121 | |
| SRP193095 | DNAJC8 | 22826 | RNAseq | 0.0520 | 0.5279 | |
| SRP219564 | DNAJC8 | 22826 | RNAseq | -0.1243 | 0.7050 | |
| TCGA | DNAJC8 | 22826 | RNAseq | 0.0781 | 0.1028 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJC8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC8 | 22826 | 0 | 6 | 24 | |
| GSE20123 | DNAJC8 | 22826 | 0 | 5 | 25 | |
| GSE43470 | DNAJC8 | 22826 | 3 | 6 | 34 | |
| GSE46452 | DNAJC8 | 22826 | 5 | 1 | 53 | |
| GSE47630 | DNAJC8 | 22826 | 8 | 3 | 29 | |
| GSE54993 | DNAJC8 | 22826 | 2 | 1 | 67 | |
| GSE54994 | DNAJC8 | 22826 | 10 | 4 | 39 | |
| GSE60625 | DNAJC8 | 22826 | 0 | 0 | 11 | |
| GSE74703 | DNAJC8 | 22826 | 2 | 4 | 30 | |
| GSE74704 | DNAJC8 | 22826 | 0 | 0 | 20 | |
| TCGA | DNAJC8 | 22826 | 11 | 23 | 62 |
Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.
Somatic mutations of DNAJC8:
Generating mutation plots.
Highly correlated genes for DNAJC8:
Showing top 20/805 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC8 | ASH2L | 0.759596 | 3 | 0 | 3 |
| DNAJC8 | STARD13 | 0.755047 | 3 | 0 | 3 |
| DNAJC8 | AP3S2 | 0.73777 | 3 | 0 | 3 |
| DNAJC8 | CDC42EP3 | 0.732185 | 6 | 0 | 5 |
| DNAJC8 | GPC4 | 0.728707 | 3 | 0 | 3 |
| DNAJC8 | MAP9 | 0.720676 | 4 | 0 | 3 |
| DNAJC8 | MYL6B | 0.70952 | 3 | 0 | 3 |
| DNAJC8 | KLF11 | 0.707897 | 5 | 0 | 5 |
| DNAJC8 | TSNAX | 0.702636 | 3 | 0 | 3 |
| DNAJC8 | UQCR10 | 0.700525 | 3 | 0 | 3 |
| DNAJC8 | SOCS5 | 0.696449 | 5 | 0 | 4 |
| DNAJC8 | RGS18 | 0.69635 | 3 | 0 | 3 |
| DNAJC8 | ZSWIM5 | 0.695853 | 3 | 0 | 3 |
| DNAJC8 | PRKD1 | 0.693188 | 4 | 0 | 4 |
| DNAJC8 | SNRNP27 | 0.692383 | 3 | 0 | 3 |
| DNAJC8 | FARP1 | 0.692338 | 3 | 0 | 3 |
| DNAJC8 | PDE4DIP | 0.690699 | 3 | 0 | 3 |
| DNAJC8 | CASD1 | 0.688903 | 4 | 0 | 3 |
| DNAJC8 | PDE9A | 0.68741 | 3 | 0 | 3 |
| DNAJC8 | MORF4L1 | 0.686936 | 6 | 0 | 5 |
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