| Full name: ADP ribosylation factor like GTPase 3 | Alias Symbol: ARFL3 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 403 | HGNC ID: HGNC:694 | Ensembl Gene: ENSG00000138175 | OMIM ID: 604695 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL3 | 403 | 202641_at | 0.4256 | 0.4233 | |
| GSE20347 | ARL3 | 403 | 202641_at | 0.2224 | 0.3244 | |
| GSE23400 | ARL3 | 403 | 202641_at | 0.1283 | 0.1405 | |
| GSE26886 | ARL3 | 403 | 202641_at | 0.7322 | 0.0004 | |
| GSE29001 | ARL3 | 403 | 202641_at | 0.3709 | 0.4009 | |
| GSE38129 | ARL3 | 403 | 202641_at | 0.2688 | 0.2547 | |
| GSE45670 | ARL3 | 403 | 202641_at | -0.0006 | 0.9977 | |
| GSE53622 | ARL3 | 403 | 90363 | -0.3719 | 0.0306 | |
| GSE53624 | ARL3 | 403 | 90363 | -0.0937 | 0.5402 | |
| GSE63941 | ARL3 | 403 | 202641_at | -0.7249 | 0.0821 | |
| GSE77861 | ARL3 | 403 | 202641_at | 0.3379 | 0.1616 | |
| GSE97050 | ARL3 | 403 | A_24_P286935 | -0.3777 | 0.4621 | |
| SRP007169 | ARL3 | 403 | RNAseq | -0.3967 | 0.4254 | |
| SRP008496 | ARL3 | 403 | RNAseq | -0.0144 | 0.9714 | |
| SRP064894 | ARL3 | 403 | RNAseq | 0.3270 | 0.2425 | |
| SRP133303 | ARL3 | 403 | RNAseq | 0.3433 | 0.0257 | |
| SRP159526 | ARL3 | 403 | RNAseq | 0.1906 | 0.4594 | |
| SRP193095 | ARL3 | 403 | RNAseq | 0.4460 | 0.0023 | |
| SRP219564 | ARL3 | 403 | RNAseq | -0.2044 | 0.6993 | |
| TCGA | ARL3 | 403 | RNAseq | -0.1357 | 0.0444 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL3 | 403 | 2 | 9 | 19 | |
| GSE20123 | ARL3 | 403 | 2 | 8 | 20 | |
| GSE43470 | ARL3 | 403 | 0 | 8 | 35 | |
| GSE46452 | ARL3 | 403 | 0 | 11 | 48 | |
| GSE47630 | ARL3 | 403 | 2 | 14 | 24 | |
| GSE54993 | ARL3 | 403 | 8 | 0 | 62 | |
| GSE54994 | ARL3 | 403 | 1 | 11 | 41 | |
| GSE60625 | ARL3 | 403 | 0 | 0 | 11 | |
| GSE74703 | ARL3 | 403 | 0 | 5 | 31 | |
| GSE74704 | ARL3 | 403 | 1 | 4 | 15 | |
| TCGA | ARL3 | 403 | 5 | 29 | 62 |
Total number of gains: 21; Total number of losses: 99; Total Number of normals: 368.
Somatic mutations of ARL3:
Generating mutation plots.
Highly correlated genes for ARL3:
Showing top 20/611 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL3 | AMIGO1 | 0.727608 | 3 | 0 | 3 |
| ARL3 | PRTFDC1 | 0.702225 | 3 | 0 | 3 |
| ARL3 | LAMTOR4 | 0.68587 | 3 | 0 | 3 |
| ARL3 | BMPR1B | 0.664805 | 3 | 0 | 3 |
| ARL3 | GPX7 | 0.657386 | 6 | 0 | 6 |
| ARL3 | BRI3 | 0.650251 | 4 | 0 | 4 |
| ARL3 | MAD2L2 | 0.646953 | 4 | 0 | 4 |
| ARL3 | NBPF20 | 0.643595 | 4 | 0 | 3 |
| ARL3 | SCG2 | 0.638495 | 4 | 0 | 3 |
| ARL3 | TMEM263 | 0.637887 | 6 | 0 | 5 |
| ARL3 | PXYLP1 | 0.636221 | 3 | 0 | 3 |
| ARL3 | ZNF449 | 0.634442 | 3 | 0 | 3 |
| ARL3 | AHSA1 | 0.630821 | 4 | 0 | 3 |
| ARL3 | HSP90AA1 | 0.628991 | 3 | 0 | 3 |
| ARL3 | PLOD3 | 0.624853 | 8 | 0 | 6 |
| ARL3 | SMARCD3 | 0.622866 | 3 | 0 | 3 |
| ARL3 | TMEM71 | 0.621944 | 5 | 0 | 4 |
| ARL3 | PITX2 | 0.621152 | 4 | 0 | 4 |
| ARL3 | PCDH18 | 0.620731 | 5 | 0 | 5 |
| ARL3 | FGF3 | 0.620704 | 5 | 0 | 4 |
For details and further investigation, click here
