| Full name: GRB10 interacting GYF protein 2 | Alias Symbol: KIAA0642|GYF2 | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 26058 | HGNC ID: HGNC:11960 | Ensembl Gene: ENSG00000204120 | OMIM ID: 612003 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GIGYF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIGYF2 | 26058 | 212261_at | -0.3569 | 0.4500 | |
| GSE20347 | GIGYF2 | 26058 | 212261_at | -0.2136 | 0.0290 | |
| GSE23400 | GIGYF2 | 26058 | 212261_at | -0.0616 | 0.1010 | |
| GSE26886 | GIGYF2 | 26058 | 212261_at | -0.4067 | 0.0163 | |
| GSE29001 | GIGYF2 | 26058 | 212261_at | -0.1488 | 0.2551 | |
| GSE38129 | GIGYF2 | 26058 | 212261_at | -0.3253 | 0.0001 | |
| GSE45670 | GIGYF2 | 26058 | 212261_at | -0.0520 | 0.6420 | |
| GSE53622 | GIGYF2 | 26058 | 85918 | -0.4592 | 0.0000 | |
| GSE53624 | GIGYF2 | 26058 | 85918 | -0.3337 | 0.0000 | |
| GSE63941 | GIGYF2 | 26058 | 212261_at | -0.0435 | 0.8530 | |
| GSE77861 | GIGYF2 | 26058 | 212261_at | -0.0009 | 0.9949 | |
| GSE97050 | GIGYF2 | 26058 | A_23_P142950 | -0.2432 | 0.3590 | |
| SRP007169 | GIGYF2 | 26058 | RNAseq | 0.1527 | 0.7432 | |
| SRP008496 | GIGYF2 | 26058 | RNAseq | 0.3636 | 0.2852 | |
| SRP064894 | GIGYF2 | 26058 | RNAseq | -0.2526 | 0.1196 | |
| SRP133303 | GIGYF2 | 26058 | RNAseq | 0.0027 | 0.9811 | |
| SRP159526 | GIGYF2 | 26058 | RNAseq | -0.0492 | 0.7804 | |
| SRP193095 | GIGYF2 | 26058 | RNAseq | -0.1652 | 0.0425 | |
| SRP219564 | GIGYF2 | 26058 | RNAseq | -0.1209 | 0.6315 | |
| TCGA | GIGYF2 | 26058 | RNAseq | -0.1605 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GIGYF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIGYF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIGYF2 | 26058 | 1 | 12 | 17 | |
| GSE20123 | GIGYF2 | 26058 | 1 | 12 | 17 | |
| GSE43470 | GIGYF2 | 26058 | 1 | 9 | 33 | |
| GSE46452 | GIGYF2 | 26058 | 0 | 5 | 54 | |
| GSE47630 | GIGYF2 | 26058 | 4 | 5 | 31 | |
| GSE54993 | GIGYF2 | 26058 | 3 | 2 | 65 | |
| GSE54994 | GIGYF2 | 26058 | 6 | 10 | 37 | |
| GSE60625 | GIGYF2 | 26058 | 0 | 3 | 8 | |
| GSE74703 | GIGYF2 | 26058 | 1 | 7 | 28 | |
| GSE74704 | GIGYF2 | 26058 | 1 | 5 | 14 | |
| TCGA | GIGYF2 | 26058 | 11 | 30 | 55 |
Total number of gains: 29; Total number of losses: 100; Total Number of normals: 359.
Somatic mutations of GIGYF2:
Generating mutation plots.
Highly correlated genes for GIGYF2:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIGYF2 | BRAF | 0.709027 | 3 | 0 | 3 |
| GIGYF2 | ZC3H6 | 0.69119 | 4 | 0 | 3 |
| GIGYF2 | SYT2 | 0.681305 | 3 | 0 | 3 |
| GIGYF2 | SLC35B4 | 0.673535 | 3 | 0 | 3 |
| GIGYF2 | HOGA1 | 0.644134 | 3 | 0 | 3 |
| GIGYF2 | MPZ | 0.639383 | 4 | 0 | 4 |
| GIGYF2 | ZC4H2 | 0.629859 | 4 | 0 | 3 |
| GIGYF2 | CASD1 | 0.611886 | 3 | 0 | 3 |
| GIGYF2 | MYO9A | 0.609784 | 4 | 0 | 3 |
| GIGYF2 | MBP | 0.603379 | 4 | 0 | 3 |
| GIGYF2 | TMEM125 | 0.602205 | 3 | 0 | 3 |
| GIGYF2 | GATA2 | 0.599714 | 4 | 0 | 3 |
| GIGYF2 | MOB2 | 0.5993 | 4 | 0 | 3 |
| GIGYF2 | ANKRD29 | 0.591603 | 4 | 0 | 3 |
| GIGYF2 | PDZRN3-AS1 | 0.590229 | 3 | 0 | 3 |
| GIGYF2 | STK16 | 0.586237 | 4 | 0 | 3 |
| GIGYF2 | FAM189A2 | 0.584094 | 6 | 0 | 5 |
| GIGYF2 | FGF10 | 0.580443 | 4 | 0 | 4 |
| GIGYF2 | MPP7 | 0.580425 | 4 | 0 | 3 |
| GIGYF2 | FAM78B | 0.578804 | 4 | 0 | 3 |
For details and further investigation, click here
