| Full name: CDC42 effector protein 3 | Alias Symbol: CEP3|UB1|BORG2 | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 10602 | HGNC ID: HGNC:16943 | Ensembl Gene: ENSG00000163171 | OMIM ID: 606133 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42EP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42EP3 | 10602 | 225685_at | -0.3967 | 0.6753 | |
| GSE20347 | CDC42EP3 | 10602 | 209288_s_at | 1.4967 | 0.0001 | |
| GSE23400 | CDC42EP3 | 10602 | 209286_at | 0.1560 | 0.3180 | |
| GSE26886 | CDC42EP3 | 10602 | 209288_s_at | 2.3683 | 0.0000 | |
| GSE29001 | CDC42EP3 | 10602 | 209288_s_at | 1.4132 | 0.0033 | |
| GSE38129 | CDC42EP3 | 10602 | 209288_s_at | 1.0245 | 0.0204 | |
| GSE45670 | CDC42EP3 | 10602 | 209288_s_at | -0.1339 | 0.8220 | |
| GSE53622 | CDC42EP3 | 10602 | 73435 | 0.0476 | 0.7990 | |
| GSE53624 | CDC42EP3 | 10602 | 73435 | 0.3420 | 0.0015 | |
| GSE63941 | CDC42EP3 | 10602 | 209288_s_at | -1.2482 | 0.0696 | |
| GSE77861 | CDC42EP3 | 10602 | 209287_s_at | 0.2718 | 0.1783 | |
| GSE97050 | CDC42EP3 | 10602 | A_33_P3331307 | -0.2678 | 0.6370 | |
| SRP007169 | CDC42EP3 | 10602 | RNAseq | 2.9596 | 0.0000 | |
| SRP008496 | CDC42EP3 | 10602 | RNAseq | 2.8219 | 0.0000 | |
| SRP064894 | CDC42EP3 | 10602 | RNAseq | 0.6520 | 0.0100 | |
| SRP133303 | CDC42EP3 | 10602 | RNAseq | 0.9472 | 0.0008 | |
| SRP159526 | CDC42EP3 | 10602 | RNAseq | 1.1344 | 0.0004 | |
| SRP193095 | CDC42EP3 | 10602 | RNAseq | 1.8061 | 0.0000 | |
| SRP219564 | CDC42EP3 | 10602 | RNAseq | 0.1572 | 0.8050 | |
| TCGA | CDC42EP3 | 10602 | RNAseq | 0.0169 | 0.8638 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by CDC42EP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42EP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42EP3 | 10602 | 10 | 1 | 19 | |
| GSE20123 | CDC42EP3 | 10602 | 9 | 1 | 20 | |
| GSE43470 | CDC42EP3 | 10602 | 3 | 0 | 40 | |
| GSE46452 | CDC42EP3 | 10602 | 1 | 4 | 54 | |
| GSE47630 | CDC42EP3 | 10602 | 7 | 0 | 33 | |
| GSE54993 | CDC42EP3 | 10602 | 0 | 5 | 65 | |
| GSE54994 | CDC42EP3 | 10602 | 10 | 0 | 43 | |
| GSE60625 | CDC42EP3 | 10602 | 0 | 3 | 8 | |
| GSE74703 | CDC42EP3 | 10602 | 3 | 0 | 33 | |
| GSE74704 | CDC42EP3 | 10602 | 9 | 1 | 10 | |
| TCGA | CDC42EP3 | 10602 | 35 | 2 | 59 |
Total number of gains: 87; Total number of losses: 17; Total Number of normals: 384.
Somatic mutations of CDC42EP3:
Generating mutation plots.
Highly correlated genes for CDC42EP3:
Showing top 20/1337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42EP3 | PDE6D | 0.775598 | 3 | 0 | 3 |
| CDC42EP3 | PHB | 0.765534 | 3 | 0 | 3 |
| CDC42EP3 | SLC38A10 | 0.761374 | 4 | 0 | 4 |
| CDC42EP3 | BIRC6 | 0.74563 | 3 | 0 | 3 |
| CDC42EP3 | TP53I13 | 0.734024 | 3 | 0 | 3 |
| CDC42EP3 | DNAJC8 | 0.732185 | 6 | 0 | 5 |
| CDC42EP3 | NBR1 | 0.728104 | 4 | 0 | 4 |
| CDC42EP3 | ZSWIM5 | 0.718139 | 3 | 0 | 3 |
| CDC42EP3 | ZNF25 | 0.71597 | 4 | 0 | 3 |
| CDC42EP3 | PIGC | 0.711665 | 4 | 0 | 4 |
| CDC42EP3 | HSPB11 | 0.710385 | 3 | 0 | 3 |
| CDC42EP3 | AFMID | 0.709094 | 3 | 0 | 3 |
| CDC42EP3 | LAMA4 | 0.708183 | 11 | 0 | 11 |
| CDC42EP3 | HMG20A | 0.707185 | 3 | 0 | 3 |
| CDC42EP3 | ZEB1 | 0.705559 | 3 | 0 | 3 |
| CDC42EP3 | DNTTIP1 | 0.703454 | 3 | 0 | 3 |
| CDC42EP3 | PI16 | 0.703372 | 3 | 0 | 3 |
| CDC42EP3 | ALPK3 | 0.702484 | 5 | 0 | 4 |
| CDC42EP3 | HMCN1 | 0.702366 | 7 | 0 | 6 |
| CDC42EP3 | PAK2 | 0.702309 | 4 | 0 | 4 |
For details and further investigation, click here
