| Full name: coiled-coil domain containing 70 | Alias Symbol: DKFZP434K1172|FLJ25853 | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 83446 | HGNC ID: HGNC:25303 | Ensembl Gene: ENSG00000123171 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC70 | 83446 | 221167_s_at | 0.0442 | 0.9040 | |
| GSE20347 | CCDC70 | 83446 | 221167_s_at | -0.0458 | 0.5025 | |
| GSE23400 | CCDC70 | 83446 | 221167_s_at | -0.0485 | 0.1626 | |
| GSE26886 | CCDC70 | 83446 | 221167_s_at | 0.2153 | 0.1165 | |
| GSE29001 | CCDC70 | 83446 | 221167_s_at | -0.3372 | 0.0215 | |
| GSE38129 | CCDC70 | 83446 | 221167_s_at | -0.0512 | 0.5399 | |
| GSE45670 | CCDC70 | 83446 | 221167_s_at | -0.1330 | 0.1115 | |
| GSE63941 | CCDC70 | 83446 | 221167_s_at | 0.2073 | 0.1005 | |
| GSE77861 | CCDC70 | 83446 | 221167_s_at | 0.0740 | 0.5803 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC70 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CCDC70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC70 | 83446 | 1 | 13 | 16 | |
| GSE20123 | CCDC70 | 83446 | 1 | 12 | 17 | |
| GSE43470 | CCDC70 | 83446 | 3 | 12 | 28 | |
| GSE46452 | CCDC70 | 83446 | 0 | 32 | 27 | |
| GSE47630 | CCDC70 | 83446 | 2 | 27 | 11 | |
| GSE54993 | CCDC70 | 83446 | 12 | 2 | 56 | |
| GSE54994 | CCDC70 | 83446 | 1 | 15 | 37 | |
| GSE60625 | CCDC70 | 83446 | 0 | 3 | 8 | |
| GSE74703 | CCDC70 | 83446 | 3 | 10 | 23 | |
| GSE74704 | CCDC70 | 83446 | 0 | 9 | 11 | |
| TCGA | CCDC70 | 83446 | 9 | 36 | 51 |
Total number of gains: 32; Total number of losses: 171; Total Number of normals: 285.
Somatic mutations of CCDC70:
Generating mutation plots.
Highly correlated genes for CCDC70:
Showing top 20/952 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC70 | ARHGEF38 | 0.710311 | 5 | 0 | 5 |
| CCDC70 | ABCA4 | 0.696202 | 3 | 0 | 3 |
| CCDC70 | EDA2R | 0.69451 | 5 | 0 | 5 |
| CCDC70 | RABEP2 | 0.689766 | 3 | 0 | 3 |
| CCDC70 | FOXN3-AS2 | 0.685901 | 5 | 0 | 5 |
| CCDC70 | P2RX6 | 0.684928 | 5 | 0 | 5 |
| CCDC70 | SLC10A2 | 0.681396 | 4 | 0 | 4 |
| CCDC70 | DRD5 | 0.67762 | 4 | 0 | 4 |
| CCDC70 | ADPRH | 0.676994 | 5 | 0 | 5 |
| CCDC70 | HS6ST1 | 0.672815 | 3 | 0 | 3 |
| CCDC70 | E2F4 | 0.668137 | 7 | 0 | 6 |
| CCDC70 | ZNF835 | 0.668014 | 4 | 0 | 3 |
| CCDC70 | PTGES2 | 0.66795 | 3 | 0 | 3 |
| CCDC70 | GPR182 | 0.661519 | 5 | 0 | 4 |
| CCDC70 | RIMS4 | 0.659809 | 3 | 0 | 3 |
| CCDC70 | HPX | 0.657694 | 8 | 0 | 7 |
| CCDC70 | NEU4 | 0.655413 | 3 | 0 | 3 |
| CCDC70 | UCP1 | 0.651893 | 6 | 0 | 5 |
| CCDC70 | KHDRBS2 | 0.650955 | 4 | 0 | 4 |
| CCDC70 | SHOX | 0.649538 | 4 | 0 | 3 |
For details and further investigation, click here
