| Full name: Rho guanine nucleotide exchange factor 38 | Alias Symbol: FLJ20184 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 54848 | HGNC ID: HGNC:25968 | Ensembl Gene: ENSG00000236699 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF38 | 54848 | 221119_at | 0.0237 | 0.9491 | |
| GSE20347 | ARHGEF38 | 54848 | 221119_at | 0.0364 | 0.7198 | |
| GSE23400 | ARHGEF38 | 54848 | 221119_at | -0.0761 | 0.0635 | |
| GSE26886 | ARHGEF38 | 54848 | 221119_at | 0.0017 | 0.9915 | |
| GSE29001 | ARHGEF38 | 54848 | 221119_at | -0.1872 | 0.3609 | |
| GSE38129 | ARHGEF38 | 54848 | 221119_at | -0.0842 | 0.2389 | |
| GSE45670 | ARHGEF38 | 54848 | 221119_at | 0.2692 | 0.0048 | |
| GSE53622 | ARHGEF38 | 54848 | 111973 | -0.0932 | 0.2774 | |
| GSE53624 | ARHGEF38 | 54848 | 111973 | 0.1199 | 0.3092 | |
| GSE63941 | ARHGEF38 | 54848 | 221119_at | 0.0516 | 0.7384 | |
| GSE77861 | ARHGEF38 | 54848 | 221119_at | -0.0092 | 0.9517 | |
| SRP133303 | ARHGEF38 | 54848 | RNAseq | -1.2457 | 0.0988 | |
| TCGA | ARHGEF38 | 54848 | RNAseq | -3.3972 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ARHGEF38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGEF38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF38 | 54848 | 0 | 12 | 18 | |
| GSE20123 | ARHGEF38 | 54848 | 0 | 12 | 18 | |
| GSE43470 | ARHGEF38 | 54848 | 0 | 13 | 30 | |
| GSE46452 | ARHGEF38 | 54848 | 1 | 36 | 22 | |
| GSE47630 | ARHGEF38 | 54848 | 0 | 20 | 20 | |
| GSE54993 | ARHGEF38 | 54848 | 9 | 0 | 61 | |
| GSE54994 | ARHGEF38 | 54848 | 1 | 10 | 42 | |
| GSE60625 | ARHGEF38 | 54848 | 0 | 3 | 8 | |
| GSE74703 | ARHGEF38 | 54848 | 0 | 11 | 25 | |
| GSE74704 | ARHGEF38 | 54848 | 0 | 6 | 14 | |
| TCGA | ARHGEF38 | 54848 | 8 | 38 | 50 |
Total number of gains: 19; Total number of losses: 161; Total Number of normals: 308.
Somatic mutations of ARHGEF38:
Generating mutation plots.
Highly correlated genes for ARHGEF38:
Showing top 20/813 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF38 | CHRNA6 | 0.732202 | 4 | 0 | 4 |
| ARHGEF38 | GPR31 | 0.728155 | 5 | 0 | 5 |
| ARHGEF38 | SLC28A2 | 0.718778 | 4 | 0 | 4 |
| ARHGEF38 | MC2R | 0.715481 | 6 | 0 | 6 |
| ARHGEF38 | CCDC70 | 0.710311 | 5 | 0 | 5 |
| ARHGEF38 | EDA2R | 0.70934 | 6 | 0 | 6 |
| ARHGEF38 | CYP11B1 | 0.708023 | 5 | 0 | 5 |
| ARHGEF38 | PRODH2 | 0.707754 | 6 | 0 | 6 |
| ARHGEF38 | G6PC2 | 0.703599 | 6 | 0 | 6 |
| ARHGEF38 | IFT122 | 0.694194 | 4 | 0 | 3 |
| ARHGEF38 | CPNE6 | 0.693018 | 3 | 0 | 3 |
| ARHGEF38 | FSTL4 | 0.692436 | 5 | 0 | 5 |
| ARHGEF38 | TMPRSS5 | 0.691421 | 5 | 0 | 5 |
| ARHGEF38 | NXPE4 | 0.691284 | 6 | 0 | 5 |
| ARHGEF38 | CCDC87 | 0.689219 | 4 | 0 | 4 |
| ARHGEF38 | KHDRBS2 | 0.684514 | 4 | 0 | 4 |
| ARHGEF38 | RNF208 | 0.683194 | 3 | 0 | 3 |
| ARHGEF38 | IMPG1 | 0.682012 | 3 | 0 | 3 |
| ARHGEF38 | KCNJ10 | 0.681747 | 4 | 0 | 4 |
| ARHGEF38 | FEZF2 | 0.68083 | 3 | 0 | 3 |
For details and further investigation, click here
