PTGES2

 

Full name: prostaglandin E synthase 2 Alias Symbol: FLJ14038
Type: protein-coding gene Cytoband: 9q34.11
Entrez ID: 80142 HGNC ID: HGNC:17822 Ensembl Gene: ENSG00000148334 OMIM ID: 608152
Drug and gene relationship at DGIdb

 

Expression of PTGES2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PTGES2 80142 218083_at 0.1870 0.4385
GSE20347 PTGES2 80142 218083_at 0.0422 0.6968
GSE23400 PTGES2 80142 218083_at 0.1400 0.0234
GSE26886 PTGES2 80142 218083_at -0.3258 0.1432
GSE29001 PTGES2 80142 218083_at 0.2024 0.4213
GSE38129 PTGES2 80142 218083_at 0.1259 0.0912
GSE45670 PTGES2 80142 218083_at 0.1334 0.1760
GSE53622 PTGES2 80142 111758 0.0641 0.4329
GSE53624 PTGES2 80142 111758 0.3391 0.0000
GSE63941 PTGES2 80142 218083_at 1.1940 0.0010
GSE77861 PTGES2 80142 218083_at 0.2036 0.1360
GSE97050 PTGES2 80142 A_24_P106953 0.1546 0.7123
SRP007169 PTGES2 80142 RNAseq 0.0499 0.9119
SRP008496 PTGES2 80142 RNAseq -0.0457 0.8483
SRP064894 PTGES2 80142 RNAseq 0.5637 0.0597
SRP133303 PTGES2 80142 RNAseq 0.3082 0.0738
SRP159526 PTGES2 80142 RNAseq 0.3723 0.0367
SRP193095 PTGES2 80142 RNAseq 0.1896 0.1390
SRP219564 PTGES2 80142 RNAseq -0.0628 0.8410
TCGA PTGES2 80142 RNAseq 0.0742 0.1747

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by PTGES2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PTGES2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PTGES2 80142 6 9 15
GSE20123 PTGES2 80142 6 9 15
GSE43470 PTGES2 80142 5 7 31
GSE46452 PTGES2 80142 6 13 40
GSE47630 PTGES2 80142 3 16 21
GSE54993 PTGES2 80142 3 3 64
GSE54994 PTGES2 80142 11 8 34
GSE60625 PTGES2 80142 0 0 11
GSE74703 PTGES2 80142 5 5 26
GSE74704 PTGES2 80142 3 7 10
TCGA PTGES2 80142 27 25 44

Total number of gains: 75; Total number of losses: 102; Total Number of normals: 311.  


 

Somatic mutations of PTGES2:

 

Generating mutation plots.

 

Highly correlated genes for PTGES2:

 

Showing top 20/633 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PTGES2MPV17L0.77918303
PTGES2WBP20.775442303
PTGES2DLL40.764961303
PTGES2C12orf450.748448303
PTGES2PRELID10.746309404
PTGES2PPP5C0.738141605
PTGES2GIGYF10.738051303
PTGES2GHDC0.728813303
PTGES2FBXO160.727666303
PTGES2CLK20.723574303
PTGES2KIAA12570.720864303
PTGES2NIT10.715991303
PTGES2GNB10.715405303
PTGES2AAMP0.710924404
PTGES2RFTN20.709374404
PTGES2AP1M20.703903504
PTGES2HOMER20.70134303
PTGES2SLC35A40.699388303
PTGES2DENND4B0.69859303
PTGES2MSH20.696108303

For details and further investigation, click here