| Full name: regulating synaptic membrane exocytosis 4 | Alias Symbol: dJ781B1.3 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 140730 | HGNC ID: HGNC:16183 | Ensembl Gene: ENSG00000101098 | OMIM ID: 611601 |
| Drug and gene relationship at DGIdb | |||
Expression of RIMS4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIMS4 | 140730 | 233299_at | 0.1969 | 0.3285 | |
| GSE26886 | RIMS4 | 140730 | 233299_at | 0.3505 | 0.0016 | |
| GSE45670 | RIMS4 | 140730 | 233299_at | 0.0462 | 0.6185 | |
| GSE53622 | RIMS4 | 140730 | 125140 | 0.0928 | 0.1720 | |
| GSE53624 | RIMS4 | 140730 | 125140 | 0.1291 | 0.1862 | |
| GSE63941 | RIMS4 | 140730 | 233299_at | 0.1451 | 0.3972 | |
| GSE77861 | RIMS4 | 140730 | 233299_at | -0.0362 | 0.8300 | |
| GSE97050 | RIMS4 | 140730 | A_32_P38645 | -0.3038 | 0.4383 | |
| SRP133303 | RIMS4 | 140730 | RNAseq | -1.1008 | 0.1034 | |
| SRP159526 | RIMS4 | 140730 | RNAseq | 1.5508 | 0.0578 | |
| TCGA | RIMS4 | 140730 | RNAseq | -2.6153 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RIMS4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIMS4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIMS4 | 140730 | 13 | 1 | 16 | |
| GSE20123 | RIMS4 | 140730 | 13 | 1 | 16 | |
| GSE43470 | RIMS4 | 140730 | 12 | 2 | 29 | |
| GSE46452 | RIMS4 | 140730 | 29 | 0 | 30 | |
| GSE47630 | RIMS4 | 140730 | 24 | 1 | 15 | |
| GSE54993 | RIMS4 | 140730 | 0 | 17 | 53 | |
| GSE54994 | RIMS4 | 140730 | 25 | 0 | 28 | |
| GSE60625 | RIMS4 | 140730 | 0 | 0 | 11 | |
| GSE74703 | RIMS4 | 140730 | 10 | 2 | 24 | |
| GSE74704 | RIMS4 | 140730 | 9 | 0 | 11 | |
| TCGA | RIMS4 | 140730 | 46 | 3 | 47 |
Total number of gains: 181; Total number of losses: 27; Total Number of normals: 280.
Somatic mutations of RIMS4:
Generating mutation plots.
Highly correlated genes for RIMS4:
Showing top 20/600 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIMS4 | P4HA3 | 0.862425 | 3 | 0 | 3 |
| RIMS4 | SCN2B | 0.797428 | 3 | 0 | 3 |
| RIMS4 | MAPK8IP2 | 0.793543 | 3 | 0 | 3 |
| RIMS4 | ZNF527 | 0.79201 | 3 | 0 | 3 |
| RIMS4 | CACNA1A | 0.773351 | 3 | 0 | 3 |
| RIMS4 | RCOR2 | 0.768961 | 3 | 0 | 3 |
| RIMS4 | RAD52 | 0.759587 | 3 | 0 | 3 |
| RIMS4 | IL20 | 0.758874 | 3 | 0 | 3 |
| RIMS4 | C20orf141 | 0.755222 | 4 | 0 | 4 |
| RIMS4 | WRAP53 | 0.7528 | 3 | 0 | 3 |
| RIMS4 | UPB1 | 0.748976 | 4 | 0 | 4 |
| RIMS4 | NLRP5 | 0.73923 | 3 | 0 | 3 |
| RIMS4 | DOHH | 0.738698 | 3 | 0 | 3 |
| RIMS4 | NPEPL1 | 0.73832 | 4 | 0 | 3 |
| RIMS4 | OR2T1 | 0.737135 | 3 | 0 | 3 |
| RIMS4 | ATXN7L2 | 0.730711 | 3 | 0 | 3 |
| RIMS4 | STK32C | 0.730396 | 4 | 0 | 3 |
| RIMS4 | TMEM59L | 0.728922 | 4 | 0 | 4 |
| RIMS4 | WDR62 | 0.724656 | 3 | 0 | 3 |
| RIMS4 | ATP2B2 | 0.724271 | 4 | 0 | 4 |
For details and further investigation, click here
