| Full name: ADP-ribosylarginine hydrolase | Alias Symbol: ARH1 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 141 | HGNC ID: HGNC:269 | Ensembl Gene: ENSG00000144843 | OMIM ID: 603081 |
| Drug and gene relationship at DGIdb | |||
Expression of ADPRH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADPRH | 141 | 207863_at | 0.0152 | 0.9637 | |
| GSE20347 | ADPRH | 141 | 207863_at | -0.0576 | 0.4509 | |
| GSE23400 | ADPRH | 141 | 207863_at | -0.0438 | 0.1501 | |
| GSE26886 | ADPRH | 141 | 238505_at | -0.1546 | 0.3752 | |
| GSE29001 | ADPRH | 141 | 207863_at | -0.0908 | 0.5112 | |
| GSE38129 | ADPRH | 141 | 207863_at | -0.1104 | 0.1772 | |
| GSE45670 | ADPRH | 141 | 228042_at | 0.0847 | 0.6776 | |
| GSE53622 | ADPRH | 141 | 25391 | -0.1509 | 0.1111 | |
| GSE53624 | ADPRH | 141 | 25391 | 0.1424 | 0.0702 | |
| GSE63941 | ADPRH | 141 | 207863_at | 0.3499 | 0.1225 | |
| GSE77861 | ADPRH | 141 | 238505_at | 0.0081 | 0.9507 | |
| GSE97050 | ADPRH | 141 | A_33_P3366053 | -0.1368 | 0.5904 | |
| SRP007169 | ADPRH | 141 | RNAseq | 1.1189 | 0.1053 | |
| SRP008496 | ADPRH | 141 | RNAseq | 1.4135 | 0.0078 | |
| SRP064894 | ADPRH | 141 | RNAseq | 0.6023 | 0.0092 | |
| SRP133303 | ADPRH | 141 | RNAseq | 0.2235 | 0.1905 | |
| SRP159526 | ADPRH | 141 | RNAseq | -0.1049 | 0.7555 | |
| SRP193095 | ADPRH | 141 | RNAseq | 0.5061 | 0.0005 | |
| SRP219564 | ADPRH | 141 | RNAseq | -0.0373 | 0.9515 | |
| TCGA | ADPRH | 141 | RNAseq | -0.1343 | 0.2671 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ADPRH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADPRH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADPRH | 141 | 18 | 0 | 12 | |
| GSE20123 | ADPRH | 141 | 18 | 0 | 12 | |
| GSE43470 | ADPRH | 141 | 21 | 1 | 21 | |
| GSE46452 | ADPRH | 141 | 14 | 5 | 40 | |
| GSE47630 | ADPRH | 141 | 16 | 5 | 19 | |
| GSE54993 | ADPRH | 141 | 2 | 6 | 62 | |
| GSE54994 | ADPRH | 141 | 30 | 4 | 19 | |
| GSE60625 | ADPRH | 141 | 0 | 6 | 5 | |
| GSE74703 | ADPRH | 141 | 17 | 1 | 18 | |
| GSE74704 | ADPRH | 141 | 13 | 0 | 7 | |
| TCGA | ADPRH | 141 | 53 | 7 | 36 |
Total number of gains: 202; Total number of losses: 35; Total Number of normals: 251.
Somatic mutations of ADPRH:
Generating mutation plots.
Highly correlated genes for ADPRH:
Showing top 20/468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADPRH | CIDEC | 0.783467 | 3 | 0 | 3 |
| ADPRH | CYGB | 0.748683 | 3 | 0 | 3 |
| ADPRH | TMEM214 | 0.739172 | 3 | 0 | 3 |
| ADPRH | BEGAIN | 0.73307 | 3 | 0 | 3 |
| ADPRH | DOCK1 | 0.723447 | 3 | 0 | 3 |
| ADPRH | TPSG1 | 0.71872 | 5 | 0 | 5 |
| ADPRH | KLHL11 | 0.70488 | 6 | 0 | 6 |
| ADPRH | PRKCI | 0.701737 | 3 | 0 | 3 |
| ADPRH | TRPM7 | 0.700556 | 3 | 0 | 3 |
| ADPRH | TCL1B | 0.696965 | 4 | 0 | 4 |
| ADPRH | CCDC7 | 0.696035 | 6 | 0 | 6 |
| ADPRH | CAV3 | 0.69527 | 8 | 0 | 8 |
| ADPRH | POLK | 0.690013 | 3 | 0 | 3 |
| ADPRH | MAPK11 | 0.689429 | 3 | 0 | 3 |
| ADPRH | CBL | 0.689082 | 6 | 0 | 4 |
| ADPRH | INO80D | 0.68486 | 5 | 0 | 4 |
| ADPRH | BSN | 0.680119 | 5 | 0 | 4 |
| ADPRH | GPR31 | 0.679912 | 6 | 0 | 5 |
| ADPRH | CCDC70 | 0.676994 | 5 | 0 | 5 |
| ADPRH | NPHS2 | 0.670655 | 6 | 0 | 6 |
For details and further investigation, click here
