| Full name: family with sequence similarity 126 member A | Alias Symbol: DRCTNNB1A|HCC|HYCC1|hyccin | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 84668 | HGNC ID: HGNC:24587 | Ensembl Gene: ENSG00000122591 | OMIM ID: 610531 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM126A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM126A | 84668 | 227239_at | -0.0949 | 0.9139 | |
| GSE26886 | FAM126A | 84668 | 227239_at | -0.0960 | 0.8153 | |
| GSE45670 | FAM126A | 84668 | 227239_at | 0.3949 | 0.0454 | |
| GSE53622 | FAM126A | 84668 | 62683 | 0.1063 | 0.3696 | |
| GSE53624 | FAM126A | 84668 | 52187 | -0.1233 | 0.3470 | |
| GSE63941 | FAM126A | 84668 | 227239_at | -1.1270 | 0.1332 | |
| GSE77861 | FAM126A | 84668 | 227239_at | 0.7786 | 0.0869 | |
| GSE97050 | FAM126A | 84668 | A_23_P8582 | 0.3013 | 0.3879 | |
| SRP007169 | FAM126A | 84668 | RNAseq | -0.4028 | 0.3304 | |
| SRP008496 | FAM126A | 84668 | RNAseq | -0.2667 | 0.3172 | |
| SRP064894 | FAM126A | 84668 | RNAseq | -0.0121 | 0.9568 | |
| SRP133303 | FAM126A | 84668 | RNAseq | 0.4347 | 0.0260 | |
| SRP159526 | FAM126A | 84668 | RNAseq | -0.3548 | 0.1827 | |
| SRP193095 | FAM126A | 84668 | RNAseq | 0.2542 | 0.1728 | |
| SRP219564 | FAM126A | 84668 | RNAseq | -0.1715 | 0.7467 | |
| TCGA | FAM126A | 84668 | RNAseq | 0.2664 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM126A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM126A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM126A | 84668 | 17 | 1 | 12 | |
| GSE20123 | FAM126A | 84668 | 17 | 1 | 12 | |
| GSE43470 | FAM126A | 84668 | 4 | 0 | 39 | |
| GSE46452 | FAM126A | 84668 | 10 | 2 | 47 | |
| GSE47630 | FAM126A | 84668 | 9 | 1 | 30 | |
| GSE54993 | FAM126A | 84668 | 0 | 6 | 64 | |
| GSE54994 | FAM126A | 84668 | 20 | 2 | 31 | |
| GSE60625 | FAM126A | 84668 | 0 | 0 | 11 | |
| GSE74703 | FAM126A | 84668 | 4 | 0 | 32 | |
| GSE74704 | FAM126A | 84668 | 11 | 1 | 8 | |
| TCGA | FAM126A | 84668 | 56 | 4 | 36 |
Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.
Somatic mutations of FAM126A:
Generating mutation plots.
Highly correlated genes for FAM126A:
Showing top 20/303 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM126A | SUMF2 | 0.823786 | 3 | 0 | 3 |
| FAM126A | COL4A1 | 0.794791 | 3 | 0 | 3 |
| FAM126A | AGRN | 0.765863 | 3 | 0 | 3 |
| FAM126A | SP100 | 0.76514 | 3 | 0 | 3 |
| FAM126A | GPR153 | 0.764724 | 3 | 0 | 3 |
| FAM126A | DDX60L | 0.753162 | 3 | 0 | 3 |
| FAM126A | AASDHPPT | 0.752192 | 3 | 0 | 3 |
| FAM126A | TNS3 | 0.750282 | 3 | 0 | 3 |
| FAM126A | ATG2B | 0.750151 | 3 | 0 | 3 |
| FAM126A | FLRT3 | 0.747487 | 3 | 0 | 3 |
| FAM126A | CCNH | 0.739973 | 3 | 0 | 3 |
| FAM126A | FNIP1 | 0.739881 | 3 | 0 | 3 |
| FAM126A | LIX1L | 0.73953 | 3 | 0 | 3 |
| FAM126A | PDE7A | 0.73409 | 3 | 0 | 3 |
| FAM126A | CDK6 | 0.733109 | 3 | 0 | 3 |
| FAM126A | DENND5A | 0.729303 | 3 | 0 | 3 |
| FAM126A | CCDC88A | 0.72866 | 3 | 0 | 3 |
| FAM126A | ITGA5 | 0.727048 | 3 | 0 | 3 |
| FAM126A | SLC35E3 | 0.723895 | 3 | 0 | 3 |
| FAM126A | RBM22 | 0.723777 | 4 | 0 | 4 |
For details and further investigation, click here
