| Full name: fibrinogen like 2 | Alias Symbol: pT49|T49 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 10875 | HGNC ID: HGNC:3696 | Ensembl Gene: ENSG00000127951 | OMIM ID: 605351 |
| Drug and gene relationship at DGIdb | |||
Expression of FGL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGL2 | 10875 | 227265_at | -1.7066 | 0.3134 | |
| GSE20347 | FGL2 | 10875 | 204834_at | -0.4163 | 0.2661 | |
| GSE23400 | FGL2 | 10875 | 204834_at | -0.6510 | 0.0260 | |
| GSE26886 | FGL2 | 10875 | 227265_at | -0.9343 | 0.1291 | |
| GSE29001 | FGL2 | 10875 | 204834_at | -0.2062 | 0.7155 | |
| GSE38129 | FGL2 | 10875 | 204834_at | -1.2699 | 0.0362 | |
| GSE45670 | FGL2 | 10875 | 227265_at | -2.5219 | 0.0000 | |
| GSE53622 | FGL2 | 10875 | 86147 | -1.5135 | 0.0000 | |
| GSE53624 | FGL2 | 10875 | 86147 | -1.1928 | 0.0000 | |
| GSE63941 | FGL2 | 10875 | 204834_at | -6.1282 | 0.0000 | |
| GSE77861 | FGL2 | 10875 | 227265_at | -0.4122 | 0.2343 | |
| GSE97050 | FGL2 | 10875 | A_33_P3332018 | -1.7615 | 0.1695 | |
| SRP007169 | FGL2 | 10875 | RNAseq | -0.2512 | 0.6270 | |
| SRP008496 | FGL2 | 10875 | RNAseq | -0.2849 | 0.3223 | |
| SRP064894 | FGL2 | 10875 | RNAseq | -0.1719 | 0.6688 | |
| SRP133303 | FGL2 | 10875 | RNAseq | -0.4626 | 0.2781 | |
| SRP159526 | FGL2 | 10875 | RNAseq | -0.2519 | 0.6557 | |
| SRP193095 | FGL2 | 10875 | RNAseq | -0.3772 | 0.0247 | |
| SRP219564 | FGL2 | 10875 | RNAseq | 0.7181 | 0.5346 | |
| TCGA | FGL2 | 10875 | RNAseq | -0.6526 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by FGL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGL2 | 10875 | 15 | 1 | 14 | |
| GSE20123 | FGL2 | 10875 | 15 | 1 | 14 | |
| GSE43470 | FGL2 | 10875 | 3 | 2 | 38 | |
| GSE46452 | FGL2 | 10875 | 11 | 0 | 48 | |
| GSE47630 | FGL2 | 10875 | 7 | 3 | 30 | |
| GSE54993 | FGL2 | 10875 | 1 | 7 | 62 | |
| GSE54994 | FGL2 | 10875 | 15 | 3 | 35 | |
| GSE60625 | FGL2 | 10875 | 0 | 0 | 11 | |
| GSE74703 | FGL2 | 10875 | 3 | 1 | 32 | |
| GSE74704 | FGL2 | 10875 | 8 | 1 | 11 | |
| TCGA | FGL2 | 10875 | 43 | 6 | 47 |
Total number of gains: 121; Total number of losses: 25; Total Number of normals: 342.
Somatic mutations of FGL2:
Generating mutation plots.
Highly correlated genes for FGL2:
Showing top 20/1263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGL2 | RASSF3 | 0.820841 | 4 | 0 | 4 |
| FGL2 | MGARP | 0.813273 | 3 | 0 | 3 |
| FGL2 | NEGR1 | 0.807892 | 6 | 0 | 6 |
| FGL2 | MRVI1 | 0.807269 | 6 | 0 | 6 |
| FGL2 | MYOC | 0.799243 | 8 | 0 | 8 |
| FGL2 | MEOX2 | 0.797271 | 8 | 0 | 8 |
| FGL2 | FLNC | 0.791363 | 9 | 0 | 8 |
| FGL2 | FENDRR | 0.790906 | 5 | 0 | 5 |
| FGL2 | BHMT2 | 0.783731 | 10 | 0 | 9 |
| FGL2 | RBM24 | 0.782136 | 6 | 0 | 6 |
| FGL2 | NFASC | 0.781948 | 6 | 0 | 6 |
| FGL2 | ASB5 | 0.77892 | 6 | 0 | 6 |
| FGL2 | MAGI2-AS3 | 0.778242 | 5 | 0 | 5 |
| FGL2 | LIMS2 | 0.771879 | 9 | 0 | 8 |
| FGL2 | PRKAR2B | 0.770467 | 10 | 0 | 10 |
| FGL2 | PARD3B | 0.769933 | 5 | 0 | 4 |
| FGL2 | HSPB7 | 0.769862 | 10 | 0 | 9 |
| FGL2 | KCNT2 | 0.76972 | 6 | 0 | 6 |
| FGL2 | SORCS1 | 0.768695 | 4 | 0 | 4 |
| FGL2 | PCDH9 | 0.765064 | 8 | 0 | 8 |
For details and further investigation, click here
