| Full name: semaphorin 5A | Alias Symbol: semF | ||
| Type: protein-coding gene | Cytoband: 5p15.31 | ||
| Entrez ID: 9037 | HGNC ID: HGNC:10736 | Ensembl Gene: ENSG00000112902 | OMIM ID: 609297 |
| Drug and gene relationship at DGIdb | |||
Expression of SEMA5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEMA5A | 9037 | 205405_at | 0.0630 | 0.9297 | |
| GSE20347 | SEMA5A | 9037 | 205405_at | -0.7881 | 0.0019 | |
| GSE23400 | SEMA5A | 9037 | 205405_at | -0.4521 | 0.0000 | |
| GSE26886 | SEMA5A | 9037 | 205405_at | -1.7087 | 0.0000 | |
| GSE29001 | SEMA5A | 9037 | 213169_at | -1.3179 | 0.0163 | |
| GSE38129 | SEMA5A | 9037 | 205405_at | -0.7656 | 0.0001 | |
| GSE45670 | SEMA5A | 9037 | 205405_at | -0.5699 | 0.0487 | |
| GSE53622 | SEMA5A | 9037 | 7999 | -0.6453 | 0.0000 | |
| GSE53624 | SEMA5A | 9037 | 7999 | -0.9384 | 0.0000 | |
| GSE63941 | SEMA5A | 9037 | 205405_at | -1.3878 | 0.0200 | |
| GSE77861 | SEMA5A | 9037 | 213169_at | -0.5275 | 0.1226 | |
| GSE97050 | SEMA5A | 9037 | A_33_P3372727 | 0.1548 | 0.5054 | |
| SRP007169 | SEMA5A | 9037 | RNAseq | -1.7245 | 0.0000 | |
| SRP008496 | SEMA5A | 9037 | RNAseq | -1.5284 | 0.0000 | |
| SRP064894 | SEMA5A | 9037 | RNAseq | -0.4992 | 0.1623 | |
| SRP133303 | SEMA5A | 9037 | RNAseq | -0.2491 | 0.4831 | |
| SRP159526 | SEMA5A | 9037 | RNAseq | -1.4304 | 0.0007 | |
| SRP193095 | SEMA5A | 9037 | RNAseq | -0.4903 | 0.0493 | |
| SRP219564 | SEMA5A | 9037 | RNAseq | -0.7983 | 0.1586 | |
| TCGA | SEMA5A | 9037 | RNAseq | -0.1430 | 0.2985 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by SEMA5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEMA5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEMA5A | 9037 | 12 | 0 | 18 | |
| GSE20123 | SEMA5A | 9037 | 12 | 0 | 18 | |
| GSE43470 | SEMA5A | 9037 | 17 | 0 | 26 | |
| GSE46452 | SEMA5A | 9037 | 6 | 22 | 31 | |
| GSE47630 | SEMA5A | 9037 | 6 | 11 | 23 | |
| GSE54993 | SEMA5A | 9037 | 5 | 5 | 60 | |
| GSE54994 | SEMA5A | 9037 | 29 | 1 | 23 | |
| GSE60625 | SEMA5A | 9037 | 0 | 0 | 11 | |
| GSE74703 | SEMA5A | 9037 | 13 | 0 | 23 | |
| GSE74704 | SEMA5A | 9037 | 11 | 0 | 9 | |
| TCGA | SEMA5A | 9037 | 58 | 3 | 35 |
Total number of gains: 169; Total number of losses: 42; Total Number of normals: 277.
Somatic mutations of SEMA5A:
Generating mutation plots.
Highly correlated genes for SEMA5A:
Showing top 20/232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEMA5A | CYB561D1 | 0.752042 | 3 | 0 | 3 |
| SEMA5A | BCDIN3D | 0.74744 | 3 | 0 | 3 |
| SEMA5A | ADAMTS17 | 0.711902 | 3 | 0 | 3 |
| SEMA5A | NISCH | 0.699213 | 5 | 0 | 5 |
| SEMA5A | SHQ1 | 0.668446 | 4 | 0 | 3 |
| SEMA5A | TRPA1 | 0.66233 | 4 | 0 | 3 |
| SEMA5A | YWHAZ | 0.662181 | 3 | 0 | 3 |
| SEMA5A | NICN1 | 0.659889 | 4 | 0 | 3 |
| SEMA5A | PDZD2 | 0.659527 | 10 | 0 | 9 |
| SEMA5A | MYLPF | 0.656381 | 3 | 0 | 3 |
| SEMA5A | PPM1F | 0.652585 | 5 | 0 | 4 |
| SEMA5A | CCDC89 | 0.652134 | 3 | 0 | 3 |
| SEMA5A | ATP12A | 0.65127 | 3 | 0 | 3 |
| SEMA5A | DEGS2 | 0.636662 | 4 | 0 | 3 |
| SEMA5A | CRELD1 | 0.634589 | 3 | 0 | 3 |
| SEMA5A | SNHG18 | 0.631126 | 6 | 0 | 5 |
| SEMA5A | PCDH1 | 0.625355 | 7 | 0 | 6 |
| SEMA5A | CYP3A5 | 0.623403 | 8 | 0 | 6 |
| SEMA5A | HCRT | 0.621177 | 4 | 0 | 3 |
| SEMA5A | FAAH2 | 0.615488 | 5 | 0 | 3 |
For details and further investigation, click here
