TMCO3

 

Full name: transmembrane and coiled-coil domains 3 Alias Symbol: FLJ20623
Type: protein-coding gene Cytoband: 13q34
Entrez ID: 55002 HGNC ID: HGNC:20329 Ensembl Gene: ENSG00000150403 OMIM ID: 617134
Drug and gene relationship at DGIdb

 

Expression of TMCO3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMCO3 55002 226050_at 0.3315 0.4946
GSE20347 TMCO3 55002 220240_s_at 0.4597 0.1408
GSE23400 TMCO3 55002 220240_s_at 0.1726 0.0061
GSE26886 TMCO3 55002 226050_at -0.4830 0.2409
GSE29001 TMCO3 55002 220240_s_at 0.3156 0.1455
GSE38129 TMCO3 55002 220240_s_at 0.5800 0.0239
GSE45670 TMCO3 55002 226050_at 0.3098 0.2538
GSE53622 TMCO3 55002 132043 0.1853 0.0710
GSE53624 TMCO3 55002 32507 0.4125 0.0088
GSE63941 TMCO3 55002 226050_at -1.6548 0.0048
GSE77861 TMCO3 55002 226050_at 0.1795 0.6790
GSE97050 TMCO3 55002 A_33_P3234643 0.1798 0.4183
SRP007169 TMCO3 55002 RNAseq 0.2703 0.4980
SRP008496 TMCO3 55002 RNAseq 0.6657 0.0155
SRP064894 TMCO3 55002 RNAseq 0.4421 0.0293
SRP133303 TMCO3 55002 RNAseq 0.5929 0.0016
SRP159526 TMCO3 55002 RNAseq 0.4122 0.2990
SRP193095 TMCO3 55002 RNAseq 0.1185 0.6087
SRP219564 TMCO3 55002 RNAseq 0.1884 0.5008
TCGA TMCO3 55002 RNAseq -0.2294 0.0025

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by TMCO3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMCO3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMCO3 55002 7 12 11
GSE20123 TMCO3 55002 7 11 12
GSE43470 TMCO3 55002 4 13 26
GSE46452 TMCO3 55002 3 31 25
GSE47630 TMCO3 55002 3 26 11
GSE54993 TMCO3 55002 12 3 55
GSE54994 TMCO3 55002 9 10 34
GSE60625 TMCO3 55002 0 3 8
GSE74703 TMCO3 55002 3 10 23
GSE74704 TMCO3 55002 4 9 7
TCGA TMCO3 55002 20 32 44

Total number of gains: 72; Total number of losses: 160; Total Number of normals: 256.  

 

Somatic mutations of TMCO3:

 

Generating mutation plots.

 

Highly correlated genes for TMCO3:

 

Showing top 20/60 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMCO3EFNA40.703608303
TMCO3CCDC890.691636403
TMCO3GDF150.679372403
TMCO3BCDIN3D0.671652303
TMCO3POLE40.670424504
TMCO3FBXL150.669076303
TMCO3MOB1B0.665831303
TMCO3ALKBH50.664188403
TMCO3MCF2L0.649929504
TMCO3ZKSCAN20.649392403
TMCO3POC1A0.645753403
TMCO3NTHL10.639359403
TMCO3TMEM1820.63128403
TMCO3TCEAL70.630828403
TMCO3TMEM1010.626089303
TMCO3TP53INP10.625816403
TMCO3ZNF5260.624991403
TMCO3CUL4A0.6227911007
TMCO3SFT2D10.621481403
TMCO3IFT270.620232604

For details and further investigation, click here