| Full name: cadherin 12 | Alias Symbol: Br-cadherin|CDHB | ||
| Type: protein-coding gene | Cytoband: 5p14.3 | ||
| Entrez ID: 1010 | HGNC ID: HGNC:1751 | Ensembl Gene: ENSG00000154162 | OMIM ID: 600562 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH12 | 1010 | 207149_at | -0.2171 | 0.6511 | |
| GSE20347 | CDH12 | 1010 | 207149_at | 0.0728 | 0.5950 | |
| GSE23400 | CDH12 | 1010 | 207149_at | -0.0363 | 0.1495 | |
| GSE26886 | CDH12 | 1010 | 207149_at | 0.3585 | 0.4086 | |
| GSE29001 | CDH12 | 1010 | 207149_at | 0.4252 | 0.4371 | |
| GSE38129 | CDH12 | 1010 | 207149_at | 0.1297 | 0.4838 | |
| GSE45670 | CDH12 | 1010 | 207149_at | 0.2675 | 0.5804 | |
| GSE53622 | CDH12 | 1010 | 45443 | 0.3138 | 0.0280 | |
| GSE53624 | CDH12 | 1010 | 45443 | 0.0888 | 0.4209 | |
| GSE63941 | CDH12 | 1010 | 207149_at | 0.6998 | 0.6139 | |
| GSE77861 | CDH12 | 1010 | 207149_at | -0.0602 | 0.4941 | |
| SRP064894 | CDH12 | 1010 | RNAseq | -0.2453 | 0.4368 | |
| SRP133303 | CDH12 | 1010 | RNAseq | -0.3319 | 0.3033 | |
| SRP159526 | CDH12 | 1010 | RNAseq | 1.6627 | 0.0598 | |
| SRP193095 | CDH12 | 1010 | RNAseq | 0.8138 | 0.0038 | |
| SRP219564 | CDH12 | 1010 | RNAseq | 0.3264 | 0.3874 | |
| TCGA | CDH12 | 1010 | RNAseq | 1.5822 | 0.0801 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDH12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH12 | 1010 | 9 | 0 | 21 | |
| GSE20123 | CDH12 | 1010 | 9 | 0 | 21 | |
| GSE43470 | CDH12 | 1010 | 16 | 0 | 27 | |
| GSE46452 | CDH12 | 1010 | 6 | 22 | 31 | |
| GSE47630 | CDH12 | 1010 | 6 | 11 | 23 | |
| GSE54993 | CDH12 | 1010 | 5 | 4 | 61 | |
| GSE54994 | CDH12 | 1010 | 26 | 6 | 21 | |
| GSE60625 | CDH12 | 1010 | 0 | 0 | 11 | |
| GSE74703 | CDH12 | 1010 | 12 | 0 | 24 | |
| GSE74704 | CDH12 | 1010 | 8 | 0 | 12 | |
| TCGA | CDH12 | 1010 | 57 | 3 | 36 |
Total number of gains: 154; Total number of losses: 46; Total Number of normals: 288.
Somatic mutations of CDH12:
Generating mutation plots.
Highly correlated genes for CDH12:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH12 | SLC14A1 | 0.871345 | 3 | 0 | 3 |
| CDH12 | AGR3 | 0.810192 | 3 | 0 | 3 |
| CDH12 | PLEKHS1 | 0.78989 | 3 | 0 | 3 |
| CDH12 | OLFM4 | 0.782455 | 3 | 0 | 3 |
| CDH12 | BEX1 | 0.759616 | 5 | 0 | 5 |
| CDH12 | QPRT | 0.694029 | 3 | 0 | 3 |
| CDH12 | CLUL1 | 0.675539 | 5 | 0 | 4 |
| CDH12 | ODAM | 0.674037 | 5 | 0 | 4 |
| CDH12 | EFHD1 | 0.666425 | 3 | 0 | 3 |
| CDH12 | NPY1R | 0.651036 | 4 | 0 | 3 |
| CDH12 | LIFR | 0.649047 | 4 | 0 | 3 |
| CDH12 | SAGE1 | 0.646766 | 4 | 0 | 3 |
| CDH12 | LSAMP | 0.643512 | 4 | 0 | 3 |
| CDH12 | PROM1 | 0.635588 | 5 | 0 | 3 |
| CDH12 | SYT13 | 0.61827 | 4 | 0 | 3 |
| CDH12 | ASRGL1 | 0.617042 | 3 | 0 | 3 |
| CDH12 | SLCO4C1 | 0.613985 | 3 | 0 | 3 |
| CDH12 | COL8A2 | 0.60451 | 4 | 0 | 3 |
| CDH12 | TAPT1-AS1 | 0.600554 | 3 | 0 | 3 |
| CDH12 | PPP1R9A | 0.589242 | 4 | 0 | 3 |
For details and further investigation, click here
