| Full name: prominin 1 | Alias Symbol: AC133|CD133|RP41|CORD12 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 8842 | HGNC ID: HGNC:9454 | Ensembl Gene: ENSG00000007062 | OMIM ID: 604365 |
| Drug and gene relationship at DGIdb | |||
Expression of PROM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PROM1 | 8842 | 204304_s_at | -2.3830 | 0.1374 | |
| GSE20347 | PROM1 | 8842 | 204304_s_at | 0.0615 | 0.9064 | |
| GSE23400 | PROM1 | 8842 | 204304_s_at | -0.8079 | 0.0000 | |
| GSE26886 | PROM1 | 8842 | 204304_s_at | 0.4353 | 0.1632 | |
| GSE29001 | PROM1 | 8842 | 204304_s_at | 0.1102 | 0.8275 | |
| GSE38129 | PROM1 | 8842 | 204304_s_at | -0.5745 | 0.2274 | |
| GSE45670 | PROM1 | 8842 | 204304_s_at | -2.8227 | 0.0000 | |
| GSE53622 | PROM1 | 8842 | 25376 | -1.7141 | 0.0000 | |
| GSE53624 | PROM1 | 8842 | 25376 | -2.6254 | 0.0000 | |
| GSE63941 | PROM1 | 8842 | 204304_s_at | -1.0043 | 0.5090 | |
| GSE77861 | PROM1 | 8842 | 204304_s_at | 0.3294 | 0.4505 | |
| GSE97050 | PROM1 | 8842 | A_33_P3389842 | -0.2096 | 0.4724 | |
| SRP064894 | PROM1 | 8842 | RNAseq | -2.7965 | 0.0000 | |
| SRP133303 | PROM1 | 8842 | RNAseq | -2.9449 | 0.0000 | |
| SRP159526 | PROM1 | 8842 | RNAseq | -0.4369 | 0.5777 | |
| SRP219564 | PROM1 | 8842 | RNAseq | -1.3271 | 0.1329 | |
| TCGA | PROM1 | 8842 | RNAseq | -1.7992 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PROM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PROM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PROM1 | 8842 | 0 | 18 | 12 | |
| GSE20123 | PROM1 | 8842 | 0 | 18 | 12 | |
| GSE43470 | PROM1 | 8842 | 1 | 15 | 27 | |
| GSE46452 | PROM1 | 8842 | 1 | 36 | 22 | |
| GSE47630 | PROM1 | 8842 | 1 | 19 | 20 | |
| GSE54993 | PROM1 | 8842 | 10 | 0 | 60 | |
| GSE54994 | PROM1 | 8842 | 4 | 12 | 37 | |
| GSE60625 | PROM1 | 8842 | 0 | 0 | 11 | |
| GSE74703 | PROM1 | 8842 | 1 | 13 | 22 | |
| GSE74704 | PROM1 | 8842 | 0 | 11 | 9 | |
| TCGA | PROM1 | 8842 | 9 | 47 | 40 |
Total number of gains: 27; Total number of losses: 189; Total Number of normals: 272.
Somatic mutations of PROM1:
Generating mutation plots.
Highly correlated genes for PROM1:
Showing top 20/556 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PROM1 | BPIFB1 | 0.755737 | 7 | 0 | 7 |
| PROM1 | AFF3 | 0.738389 | 3 | 0 | 3 |
| PROM1 | C9orf152 | 0.701748 | 4 | 0 | 4 |
| PROM1 | SMTNL2 | 0.696406 | 5 | 0 | 4 |
| PROM1 | C6orf58 | 0.695154 | 5 | 0 | 5 |
| PROM1 | CYP4V2 | 0.69464 | 3 | 0 | 3 |
| PROM1 | SCGB3A1 | 0.694525 | 7 | 0 | 7 |
| PROM1 | FGF3 | 0.694436 | 5 | 0 | 4 |
| PROM1 | GFRA1 | 0.693509 | 7 | 0 | 7 |
| PROM1 | MIA | 0.689264 | 11 | 0 | 10 |
| PROM1 | LINC01082 | 0.686941 | 4 | 0 | 4 |
| PROM1 | MUC5B | 0.683876 | 6 | 0 | 6 |
| PROM1 | CNRIP1 | 0.680845 | 3 | 0 | 3 |
| PROM1 | FILIP1 | 0.679916 | 3 | 0 | 3 |
| PROM1 | ADAMTS9-AS2 | 0.678905 | 4 | 0 | 4 |
| PROM1 | PHLPP1 | 0.675936 | 3 | 0 | 3 |
| PROM1 | FABP7 | 0.67408 | 5 | 0 | 4 |
| PROM1 | PDK4 | 0.670936 | 4 | 0 | 4 |
| PROM1 | AZGP1 | 0.66798 | 10 | 0 | 8 |
| PROM1 | MYRIP | 0.665007 | 7 | 0 | 6 |
For details and further investigation, click here
