| Full name: solute carrier organic anion transporter family member 4C1 | Alias Symbol: SLC21A20|OATP4C1|OATPX|OATP-H | ||
| Type: protein-coding gene | Cytoband: 5q21.1 | ||
| Entrez ID: 353189 | HGNC ID: HGNC:23612 | Ensembl Gene: ENSG00000173930 | OMIM ID: 609013 |
| Drug and gene relationship at DGIdb | |||
Expression of SLCO4C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLCO4C1 | 353189 | 207596_at | 0.0844 | 0.7030 | |
| GSE20347 | SLCO4C1 | 353189 | 222071_s_at | 0.1015 | 0.4658 | |
| GSE23400 | SLCO4C1 | 353189 | 207596_at | -0.0258 | 0.2640 | |
| GSE26886 | SLCO4C1 | 353189 | 222071_s_at | 0.3845 | 0.2222 | |
| GSE29001 | SLCO4C1 | 353189 | 207596_at | -0.0095 | 0.9539 | |
| GSE38129 | SLCO4C1 | 353189 | 222071_s_at | 0.2592 | 0.1907 | |
| GSE45670 | SLCO4C1 | 353189 | 222071_s_at | -0.0155 | 0.9558 | |
| GSE53622 | SLCO4C1 | 353189 | 100833 | -0.2175 | 0.3429 | |
| GSE53624 | SLCO4C1 | 353189 | 100833 | -0.5643 | 0.0069 | |
| GSE63941 | SLCO4C1 | 353189 | 222071_s_at | 0.4348 | 0.6580 | |
| GSE77861 | SLCO4C1 | 353189 | 222071_s_at | 0.1718 | 0.5519 | |
| SRP133303 | SLCO4C1 | 353189 | RNAseq | 0.6723 | 0.1225 | |
| SRP193095 | SLCO4C1 | 353189 | RNAseq | 0.3112 | 0.0901 | |
| TCGA | SLCO4C1 | 353189 | RNAseq | 1.9576 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLCO4C1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLCO4C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLCO4C1 | 353189 | 1 | 13 | 16 | |
| GSE20123 | SLCO4C1 | 353189 | 1 | 13 | 16 | |
| GSE43470 | SLCO4C1 | 353189 | 3 | 9 | 31 | |
| GSE46452 | SLCO4C1 | 353189 | 0 | 28 | 31 | |
| GSE47630 | SLCO4C1 | 353189 | 0 | 20 | 20 | |
| GSE54993 | SLCO4C1 | 353189 | 8 | 1 | 61 | |
| GSE54994 | SLCO4C1 | 353189 | 1 | 17 | 35 | |
| GSE60625 | SLCO4C1 | 353189 | 0 | 0 | 11 | |
| GSE74703 | SLCO4C1 | 353189 | 2 | 7 | 27 | |
| GSE74704 | SLCO4C1 | 353189 | 1 | 7 | 12 | |
| TCGA | SLCO4C1 | 353189 | 3 | 42 | 51 |
Total number of gains: 20; Total number of losses: 157; Total Number of normals: 311.
Somatic mutations of SLCO4C1:
Generating mutation plots.
Highly correlated genes for SLCO4C1:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLCO4C1 | GDAP1 | 0.758322 | 3 | 0 | 3 |
| SLCO4C1 | SLC13A1 | 0.708128 | 3 | 0 | 3 |
| SLCO4C1 | TMPRSS15 | 0.707481 | 4 | 0 | 4 |
| SLCO4C1 | IL19 | 0.672507 | 4 | 0 | 3 |
| SLCO4C1 | GRK4 | 0.640603 | 3 | 0 | 3 |
| SLCO4C1 | TRPM4 | 0.624368 | 3 | 0 | 3 |
| SLCO4C1 | DMC1 | 0.623977 | 4 | 0 | 3 |
| SLCO4C1 | TAS2R9 | 0.616771 | 3 | 0 | 3 |
| SLCO4C1 | ZMAT4 | 0.614679 | 5 | 0 | 3 |
| SLCO4C1 | CDH12 | 0.613985 | 3 | 0 | 3 |
| SLCO4C1 | HDAC11 | 0.609162 | 3 | 0 | 3 |
| SLCO4C1 | GABRB1 | 0.60851 | 4 | 0 | 3 |
| SLCO4C1 | CST4 | 0.600532 | 3 | 0 | 3 |
| SLCO4C1 | SPTSSA | 0.600168 | 3 | 0 | 3 |
| SLCO4C1 | INHBE | 0.592215 | 4 | 0 | 3 |
| SLCO4C1 | CDC25C | 0.589931 | 3 | 0 | 3 |
| SLCO4C1 | OR3A2 | 0.588873 | 3 | 0 | 3 |
| SLCO4C1 | RNF185-AS1 | 0.584382 | 3 | 0 | 3 |
| SLCO4C1 | TRDN | 0.579936 | 5 | 0 | 4 |
| SLCO4C1 | ANGPTL3 | 0.57645 | 3 | 0 | 3 |
For details and further investigation, click here
