| Full name: protein phosphatase 1 regulatory subunit 9A | Alias Symbol: Neurabin-I|KIAA1222|FLJ20068 | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 55607 | HGNC ID: HGNC:14946 | Ensembl Gene: ENSG00000158528 | OMIM ID: 602468 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R9A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R9A | 55607 | 228494_at | -1.3807 | 0.5122 | |
| GSE20347 | PPP1R9A | 55607 | 221088_s_at | 0.0699 | 0.6368 | |
| GSE23400 | PPP1R9A | 55607 | 221088_s_at | -0.1786 | 0.0000 | |
| GSE26886 | PPP1R9A | 55607 | 233985_x_at | 0.2854 | 0.0737 | |
| GSE29001 | PPP1R9A | 55607 | 221088_s_at | 0.2989 | 0.6516 | |
| GSE38129 | PPP1R9A | 55607 | 221088_s_at | -0.5204 | 0.1267 | |
| GSE45670 | PPP1R9A | 55607 | 233985_x_at | -0.2587 | 0.0479 | |
| GSE53622 | PPP1R9A | 55607 | 83541 | -2.5547 | 0.0000 | |
| GSE53624 | PPP1R9A | 55607 | 16063 | -2.5747 | 0.0000 | |
| GSE63941 | PPP1R9A | 55607 | 228494_at | 0.7303 | 0.6816 | |
| GSE77861 | PPP1R9A | 55607 | 233985_x_at | -0.1027 | 0.3315 | |
| GSE97050 | PPP1R9A | 55607 | A_33_P3286937 | -1.4443 | 0.1080 | |
| SRP064894 | PPP1R9A | 55607 | RNAseq | -1.6740 | 0.0001 | |
| SRP133303 | PPP1R9A | 55607 | RNAseq | -1.7774 | 0.0027 | |
| SRP159526 | PPP1R9A | 55607 | RNAseq | -0.8374 | 0.1037 | |
| SRP193095 | PPP1R9A | 55607 | RNAseq | 0.1270 | 0.8289 | |
| SRP219564 | PPP1R9A | 55607 | RNAseq | -1.1381 | 0.1665 | |
| TCGA | PPP1R9A | 55607 | RNAseq | -1.7426 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by PPP1R9A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R9A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R9A | 55607 | 13 | 0 | 17 | |
| GSE20123 | PPP1R9A | 55607 | 13 | 0 | 17 | |
| GSE43470 | PPP1R9A | 55607 | 7 | 3 | 33 | |
| GSE46452 | PPP1R9A | 55607 | 12 | 0 | 47 | |
| GSE47630 | PPP1R9A | 55607 | 8 | 2 | 30 | |
| GSE54993 | PPP1R9A | 55607 | 1 | 9 | 60 | |
| GSE54994 | PPP1R9A | 55607 | 16 | 2 | 35 | |
| GSE60625 | PPP1R9A | 55607 | 0 | 5 | 6 | |
| GSE74703 | PPP1R9A | 55607 | 6 | 2 | 28 | |
| GSE74704 | PPP1R9A | 55607 | 9 | 0 | 11 | |
| TCGA | PPP1R9A | 55607 | 56 | 4 | 36 |
Total number of gains: 141; Total number of losses: 27; Total Number of normals: 320.
Somatic mutations of PPP1R9A:
Generating mutation plots.
Highly correlated genes for PPP1R9A:
Showing top 20/806 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R9A | PPM1L | 0.828842 | 4 | 0 | 4 |
| PPP1R9A | MAMDC2 | 0.794509 | 4 | 0 | 4 |
| PPP1R9A | SORCS1 | 0.794466 | 4 | 0 | 4 |
| PPP1R9A | MYCN | 0.781795 | 3 | 0 | 3 |
| PPP1R9A | OMD | 0.778889 | 3 | 0 | 3 |
| PPP1R9A | CLEC3B | 0.767875 | 3 | 0 | 3 |
| PPP1R9A | ANO5 | 0.765941 | 5 | 0 | 5 |
| PPP1R9A | ILDR2 | 0.763483 | 3 | 0 | 3 |
| PPP1R9A | ZMAT1 | 0.761457 | 4 | 0 | 4 |
| PPP1R9A | NEGR1 | 0.756399 | 4 | 0 | 4 |
| PPP1R9A | KCNB1 | 0.756217 | 5 | 0 | 4 |
| PPP1R9A | PARD3B | 0.749303 | 5 | 0 | 4 |
| PPP1R9A | APOD | 0.748334 | 6 | 0 | 6 |
| PPP1R9A | PDE5A | 0.746602 | 6 | 0 | 5 |
| PPP1R9A | LONRF2 | 0.745089 | 5 | 0 | 4 |
| PPP1R9A | PLEKHS1 | 0.744963 | 3 | 0 | 3 |
| PPP1R9A | CYP21A2 | 0.744939 | 3 | 0 | 3 |
| PPP1R9A | C1QTNF7 | 0.740875 | 5 | 0 | 5 |
| PPP1R9A | CKMT2 | 0.739425 | 6 | 0 | 6 |
| PPP1R9A | PI16 | 0.738074 | 4 | 0 | 4 |
For details and further investigation, click here
