| Full name: collagen type VIII alpha 2 chain | Alias Symbol: PPCD|FECD1|PPCD2 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 1296 | HGNC ID: HGNC:2216 | Ensembl Gene: ENSG00000171812 | OMIM ID: 120252 |
| Drug and gene relationship at DGIdb | |||
Expression of COL8A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL8A2 | 1296 | 221900_at | 0.1439 | 0.8008 | |
| GSE20347 | COL8A2 | 1296 | 52651_at | 0.1046 | 0.4201 | |
| GSE23400 | COL8A2 | 1296 | 52651_at | 0.0315 | 0.6222 | |
| GSE26886 | COL8A2 | 1296 | 221900_at | -0.3814 | 0.3601 | |
| GSE29001 | COL8A2 | 1296 | 221900_at | 0.6744 | 0.0344 | |
| GSE38129 | COL8A2 | 1296 | 52651_at | 0.0621 | 0.7147 | |
| GSE45670 | COL8A2 | 1296 | 221900_at | -0.1575 | 0.7504 | |
| GSE53622 | COL8A2 | 1296 | 72158 | 0.5428 | 0.0002 | |
| GSE53624 | COL8A2 | 1296 | 72158 | 0.5000 | 0.0000 | |
| GSE63941 | COL8A2 | 1296 | 52651_at | -0.0632 | 0.9008 | |
| GSE77861 | COL8A2 | 1296 | 52651_at | -0.1499 | 0.2336 | |
| GSE97050 | COL8A2 | 1296 | A_24_P365975 | -0.1070 | 0.8941 | |
| SRP007169 | COL8A2 | 1296 | RNAseq | 2.1382 | 0.0026 | |
| SRP008496 | COL8A2 | 1296 | RNAseq | 1.8148 | 0.0010 | |
| SRP064894 | COL8A2 | 1296 | RNAseq | 0.8473 | 0.0017 | |
| SRP133303 | COL8A2 | 1296 | RNAseq | 1.1013 | 0.0080 | |
| SRP193095 | COL8A2 | 1296 | RNAseq | 1.2920 | 0.0000 | |
| SRP219564 | COL8A2 | 1296 | RNAseq | 0.2908 | 0.5697 | |
| TCGA | COL8A2 | 1296 | RNAseq | 0.1401 | 0.3077 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by COL8A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL8A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL8A2 | 1296 | 3 | 5 | 22 | |
| GSE20123 | COL8A2 | 1296 | 3 | 4 | 23 | |
| GSE43470 | COL8A2 | 1296 | 7 | 2 | 34 | |
| GSE46452 | COL8A2 | 1296 | 4 | 1 | 54 | |
| GSE47630 | COL8A2 | 1296 | 8 | 3 | 29 | |
| GSE54993 | COL8A2 | 1296 | 1 | 1 | 68 | |
| GSE54994 | COL8A2 | 1296 | 11 | 2 | 40 | |
| GSE60625 | COL8A2 | 1296 | 0 | 0 | 11 | |
| GSE74703 | COL8A2 | 1296 | 6 | 1 | 29 | |
| GSE74704 | COL8A2 | 1296 | 2 | 0 | 18 | |
| TCGA | COL8A2 | 1296 | 11 | 19 | 66 |
Total number of gains: 56; Total number of losses: 38; Total Number of normals: 394.
Somatic mutations of COL8A2:
Generating mutation plots.
Highly correlated genes for COL8A2:
Showing top 20/253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL8A2 | CNIH3 | 0.741939 | 3 | 0 | 3 |
| COL8A2 | ENC1 | 0.713102 | 3 | 0 | 3 |
| COL8A2 | ALDH1L2 | 0.700702 | 4 | 0 | 3 |
| COL8A2 | TRIM23 | 0.692839 | 3 | 0 | 3 |
| COL8A2 | NGB | 0.689259 | 3 | 0 | 3 |
| COL8A2 | RORB | 0.684292 | 3 | 0 | 3 |
| COL8A2 | KIF3A | 0.670694 | 3 | 0 | 3 |
| COL8A2 | EGLN2 | 0.666585 | 3 | 0 | 3 |
| COL8A2 | IL17RD | 0.664633 | 3 | 0 | 3 |
| COL8A2 | MEX3B | 0.664477 | 4 | 0 | 4 |
| COL8A2 | TSHZ3 | 0.659713 | 4 | 0 | 4 |
| COL8A2 | HMCN1 | 0.656806 | 3 | 0 | 3 |
| COL8A2 | ARMCX2 | 0.656367 | 5 | 0 | 4 |
| COL8A2 | CD36 | 0.652272 | 3 | 0 | 3 |
| COL8A2 | GLIS2 | 0.648544 | 6 | 0 | 5 |
| COL8A2 | GFRA1 | 0.647892 | 5 | 0 | 4 |
| COL8A2 | CHRM4 | 0.645906 | 3 | 0 | 3 |
| COL8A2 | DNALI1 | 0.645 | 3 | 0 | 3 |
| COL8A2 | C10orf82 | 0.64288 | 3 | 0 | 3 |
| COL8A2 | CLSTN2 | 0.641771 | 3 | 0 | 3 |
For details and further investigation, click here
