| Full name: EF-hand domain family member D1 | Alias Symbol: FLJ13612 | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 80303 | HGNC ID: HGNC:29556 | Ensembl Gene: ENSG00000115468 | OMIM ID: 611617 |
| Drug and gene relationship at DGIdb | |||
Expression of EFHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFHD1 | 80303 | 209343_at | -0.9260 | 0.2929 | |
| GSE20347 | EFHD1 | 80303 | 209343_at | -0.0208 | 0.9006 | |
| GSE23400 | EFHD1 | 80303 | 209343_at | -0.3290 | 0.0000 | |
| GSE26886 | EFHD1 | 80303 | 209343_at | 1.0633 | 0.0759 | |
| GSE29001 | EFHD1 | 80303 | 209343_at | 0.0322 | 0.9564 | |
| GSE38129 | EFHD1 | 80303 | 209343_at | -0.6499 | 0.0225 | |
| GSE45670 | EFHD1 | 80303 | 209343_at | -2.0269 | 0.0000 | |
| GSE53622 | EFHD1 | 80303 | 35593 | -0.8214 | 0.0000 | |
| GSE53624 | EFHD1 | 80303 | 35593 | -1.3404 | 0.0000 | |
| GSE63941 | EFHD1 | 80303 | 209343_at | 1.2825 | 0.2036 | |
| GSE77861 | EFHD1 | 80303 | 209343_at | 0.1901 | 0.3539 | |
| GSE97050 | EFHD1 | 80303 | A_33_P3418716 | -0.2718 | 0.6998 | |
| SRP064894 | EFHD1 | 80303 | RNAseq | -0.5106 | 0.1896 | |
| SRP133303 | EFHD1 | 80303 | RNAseq | -1.7701 | 0.0000 | |
| SRP159526 | EFHD1 | 80303 | RNAseq | -0.1424 | 0.8492 | |
| SRP219564 | EFHD1 | 80303 | RNAseq | -0.4734 | 0.5137 | |
| TCGA | EFHD1 | 80303 | RNAseq | -0.5851 | 0.0040 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by EFHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFHD1 | 80303 | 1 | 12 | 17 | |
| GSE20123 | EFHD1 | 80303 | 1 | 12 | 17 | |
| GSE43470 | EFHD1 | 80303 | 1 | 8 | 34 | |
| GSE46452 | EFHD1 | 80303 | 0 | 5 | 54 | |
| GSE47630 | EFHD1 | 80303 | 4 | 5 | 31 | |
| GSE54993 | EFHD1 | 80303 | 3 | 2 | 65 | |
| GSE54994 | EFHD1 | 80303 | 6 | 10 | 37 | |
| GSE60625 | EFHD1 | 80303 | 0 | 3 | 8 | |
| GSE74703 | EFHD1 | 80303 | 1 | 6 | 29 | |
| GSE74704 | EFHD1 | 80303 | 1 | 5 | 14 | |
| TCGA | EFHD1 | 80303 | 11 | 30 | 55 |
Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.
Somatic mutations of EFHD1:
Generating mutation plots.
Highly correlated genes for EFHD1:
Showing top 20/649 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFHD1 | SLC8A1 | 0.787982 | 3 | 0 | 3 |
| EFHD1 | ADAMTS9-AS2 | 0.756766 | 4 | 0 | 4 |
| EFHD1 | ABCA6 | 0.749675 | 6 | 0 | 5 |
| EFHD1 | RASD2 | 0.732149 | 3 | 0 | 3 |
| EFHD1 | PEG3 | 0.73029 | 5 | 0 | 4 |
| EFHD1 | ITGA7 | 0.714078 | 9 | 0 | 9 |
| EFHD1 | PDK4 | 0.710688 | 6 | 0 | 6 |
| EFHD1 | ENPP2 | 0.710408 | 3 | 0 | 3 |
| EFHD1 | PRKAR2B | 0.706429 | 10 | 0 | 9 |
| EFHD1 | XKR4 | 0.70457 | 6 | 0 | 6 |
| EFHD1 | DCLK1 | 0.699448 | 9 | 0 | 9 |
| EFHD1 | FXYD1 | 0.697965 | 7 | 0 | 6 |
| EFHD1 | VIT | 0.697643 | 4 | 0 | 4 |
| EFHD1 | RAB33B | 0.692003 | 4 | 0 | 4 |
| EFHD1 | FRZB | 0.687679 | 9 | 0 | 8 |
| EFHD1 | PARVA | 0.68706 | 5 | 0 | 4 |
| EFHD1 | CBX7 | 0.686795 | 9 | 0 | 7 |
| EFHD1 | RGS7BP | 0.684526 | 6 | 0 | 5 |
| EFHD1 | C8orf88 | 0.683411 | 3 | 0 | 3 |
| EFHD1 | RNASE4 | 0.681126 | 6 | 0 | 5 |
For details and further investigation, click here
