| Full name: pleckstrin homology domain containing S1 | Alias Symbol: FLJ23537|bA211N11.2 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 79949 | HGNC ID: HGNC:26285 | Ensembl Gene: ENSG00000148735 | OMIM ID: |
Expression of PLEKHS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLEKHS1 | 79949 | 219857_at | 0.0369 | 0.9686 | |
| GSE20347 | PLEKHS1 | 79949 | 219857_at | 0.0460 | 0.6346 | |
| GSE23400 | PLEKHS1 | 79949 | 219857_at | -0.0520 | 0.0241 | |
| GSE26886 | PLEKHS1 | 79949 | 219857_at | 0.4740 | 0.0965 | |
| GSE29001 | PLEKHS1 | 79949 | 219857_at | 0.2749 | 0.1083 | |
| GSE38129 | PLEKHS1 | 79949 | 219857_at | 0.0137 | 0.8666 | |
| GSE45670 | PLEKHS1 | 79949 | 219857_at | 0.0952 | 0.7860 | |
| GSE53622 | PLEKHS1 | 79949 | 43004 | -0.1429 | 0.4354 | |
| GSE53624 | PLEKHS1 | 79949 | 43004 | 0.0838 | 0.6627 | |
| GSE63941 | PLEKHS1 | 79949 | 219857_at | 0.3614 | 0.7295 | |
| GSE77861 | PLEKHS1 | 79949 | 219857_at | -0.0110 | 0.9247 | |
| SRP064894 | PLEKHS1 | 79949 | RNAseq | -0.7183 | 0.1714 | |
| SRP133303 | PLEKHS1 | 79949 | RNAseq | -0.6855 | 0.2467 | |
| SRP159526 | PLEKHS1 | 79949 | RNAseq | -0.0947 | 0.9245 | |
| SRP193095 | PLEKHS1 | 79949 | RNAseq | 0.4404 | 0.3976 | |
| SRP219564 | PLEKHS1 | 79949 | RNAseq | 0.9710 | 0.3907 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PLEKHS1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PLEKHS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLEKHS1 | 79949 | 1 | 8 | 21 | |
| GSE20123 | PLEKHS1 | 79949 | 1 | 7 | 22 | |
| GSE43470 | PLEKHS1 | 79949 | 0 | 9 | 34 | |
| GSE46452 | PLEKHS1 | 79949 | 0 | 11 | 48 | |
| GSE47630 | PLEKHS1 | 79949 | 2 | 14 | 24 | |
| GSE54993 | PLEKHS1 | 79949 | 8 | 0 | 62 | |
| GSE54994 | PLEKHS1 | 79949 | 1 | 10 | 42 | |
| GSE60625 | PLEKHS1 | 79949 | 0 | 0 | 11 | |
| GSE74703 | PLEKHS1 | 79949 | 0 | 6 | 30 | |
| GSE74704 | PLEKHS1 | 79949 | 1 | 3 | 16 | |
| TCGA | PLEKHS1 | 79949 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of PLEKHS1:
Generating mutation plots.
Highly correlated genes for PLEKHS1:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLEKHS1 | CDH12 | 0.78989 | 3 | 0 | 3 |
| PLEKHS1 | PPP1R9A | 0.744963 | 3 | 0 | 3 |
| PLEKHS1 | BPIFB1 | 0.729128 | 3 | 0 | 3 |
| PLEKHS1 | BRINP3 | 0.688707 | 3 | 0 | 3 |
| PLEKHS1 | ARNT2 | 0.667425 | 3 | 0 | 3 |
| PLEKHS1 | LINC01305 | 0.657538 | 3 | 0 | 3 |
| PLEKHS1 | CTAG2 | 0.65131 | 4 | 0 | 3 |
| PLEKHS1 | SYF2 | 0.640671 | 3 | 0 | 3 |
| PLEKHS1 | PDGFRL | 0.638957 | 3 | 0 | 3 |
| PLEKHS1 | THBS4 | 0.630305 | 3 | 0 | 3 |
| PLEKHS1 | PHKA2 | 0.617437 | 4 | 0 | 3 |
| PLEKHS1 | ZNF112 | 0.607124 | 4 | 0 | 3 |
| PLEKHS1 | SLC4A4 | 0.598671 | 3 | 0 | 3 |
| PLEKHS1 | CP | 0.597278 | 5 | 0 | 3 |
| PLEKHS1 | CLDN3 | 0.593332 | 4 | 0 | 3 |
| PLEKHS1 | SLC34A2 | 0.585971 | 5 | 0 | 3 |
| PLEKHS1 | SCMH1 | 0.583329 | 3 | 0 | 3 |
| PLEKHS1 | UGT8 | 0.579304 | 3 | 0 | 3 |
| PLEKHS1 | ZNF45 | 0.579183 | 4 | 0 | 3 |
| PLEKHS1 | SPICE1 | 0.562149 | 3 | 0 | 3 |
For details and further investigation, click here
