| Full name: late cornified envelope 1D | Alias Symbol: LEP4 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 353134 | HGNC ID: HGNC:29465 | Ensembl Gene: ENSG00000172155 | OMIM ID: 612606 |
| Drug and gene relationship at DGIdb | |||
Expression of LCE1D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LCE1D | 353134 | 49728 | 0.0652 | 0.3968 | |
| GSE53624 | LCE1D | 353134 | 49728 | 0.1705 | 0.0810 | |
| GSE97050 | LCE1D | 353134 | A_23_P375524 | 0.3280 | 0.2156 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCE1D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCE1D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCE1D | 353134 | 15 | 0 | 15 | |
| GSE20123 | LCE1D | 353134 | 15 | 0 | 15 | |
| GSE43470 | LCE1D | 353134 | 6 | 2 | 35 | |
| GSE46452 | LCE1D | 353134 | 3 | 1 | 55 | |
| GSE47630 | LCE1D | 353134 | 15 | 0 | 25 | |
| GSE54993 | LCE1D | 353134 | 0 | 4 | 66 | |
| GSE54994 | LCE1D | 353134 | 15 | 0 | 38 | |
| GSE60625 | LCE1D | 353134 | 0 | 0 | 11 | |
| GSE74703 | LCE1D | 353134 | 6 | 1 | 29 | |
| GSE74704 | LCE1D | 353134 | 7 | 0 | 13 | |
| TCGA | LCE1D | 353134 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of LCE1D:
Generating mutation plots.
Highly correlated genes for LCE1D:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCE1D | GLI4 | 0.769129 | 3 | 0 | 3 |
| LCE1D | CDH22 | 0.763316 | 3 | 0 | 3 |
| LCE1D | ACE | 0.744694 | 3 | 0 | 3 |
| LCE1D | CD72 | 0.737252 | 3 | 0 | 3 |
| LCE1D | TSPAN11 | 0.731525 | 3 | 0 | 3 |
| LCE1D | OR2H1 | 0.714733 | 3 | 0 | 3 |
| LCE1D | CCL25 | 0.70609 | 3 | 0 | 3 |
| LCE1D | PVALB | 0.706005 | 3 | 0 | 3 |
| LCE1D | SLC39A5 | 0.705397 | 3 | 0 | 3 |
| LCE1D | KCNH3 | 0.70334 | 3 | 0 | 3 |
| LCE1D | OGFR | 0.701343 | 3 | 0 | 3 |
| LCE1D | KCP | 0.698937 | 3 | 0 | 3 |
| LCE1D | ANKDD1A | 0.696287 | 3 | 0 | 3 |
| LCE1D | CASS4 | 0.696062 | 3 | 0 | 3 |
| LCE1D | RIMBP2 | 0.694857 | 3 | 0 | 3 |
| LCE1D | PRKCG | 0.693897 | 3 | 0 | 3 |
| LCE1D | ZNF843 | 0.693501 | 3 | 0 | 3 |
| LCE1D | C19orf44 | 0.6913 | 3 | 0 | 3 |
| LCE1D | SUN5 | 0.689846 | 3 | 0 | 3 |
| LCE1D | OR4D6 | 0.681111 | 3 | 0 | 3 |
For details and further investigation, click here
