| Full name: chromosome 11 open reading frame 86 | Alias Symbol: FLJ22675 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 254439 | HGNC ID: HGNC:34442 | Ensembl Gene: ENSG00000173237 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf86:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf86 | 254439 | 233938_at | -0.1551 | 0.4662 | |
| GSE26886 | C11orf86 | 254439 | 233938_at | -0.0492 | 0.8196 | |
| GSE45670 | C11orf86 | 254439 | 233938_at | -0.2008 | 0.0426 | |
| GSE53622 | C11orf86 | 254439 | 107008 | 0.2600 | 0.0532 | |
| GSE53624 | C11orf86 | 254439 | 107008 | 0.4576 | 0.0035 | |
| GSE63941 | C11orf86 | 254439 | 233938_at | -0.0928 | 0.5644 | |
| GSE77861 | C11orf86 | 254439 | 233938_at | -0.1384 | 0.4735 | |
| GSE97050 | C11orf86 | 254439 | A_24_P392151 | 0.2639 | 0.2580 | |
| TCGA | C11orf86 | 254439 | RNAseq | -2.0779 | 0.0733 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C11orf86 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf86:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf86 | 254439 | 9 | 3 | 18 | |
| GSE20123 | C11orf86 | 254439 | 9 | 3 | 18 | |
| GSE43470 | C11orf86 | 254439 | 6 | 1 | 36 | |
| GSE46452 | C11orf86 | 254439 | 12 | 3 | 44 | |
| GSE47630 | C11orf86 | 254439 | 9 | 4 | 27 | |
| GSE54993 | C11orf86 | 254439 | 3 | 0 | 67 | |
| GSE54994 | C11orf86 | 254439 | 12 | 5 | 36 | |
| GSE60625 | C11orf86 | 254439 | 0 | 3 | 8 | |
| GSE74703 | C11orf86 | 254439 | 4 | 0 | 32 | |
| GSE74704 | C11orf86 | 254439 | 7 | 1 | 12 | |
| TCGA | C11orf86 | 254439 | 26 | 9 | 61 |
Total number of gains: 97; Total number of losses: 32; Total Number of normals: 359.
Somatic mutations of C11orf86:
Generating mutation plots.
Highly correlated genes for C11orf86:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf86 | MAP3K10 | 0.851948 | 3 | 0 | 3 |
| C11orf86 | C3orf36 | 0.799416 | 3 | 0 | 3 |
| C11orf86 | LRCH4 | 0.773548 | 3 | 0 | 3 |
| C11orf86 | KIF19 | 0.771849 | 4 | 0 | 4 |
| C11orf86 | C2orf72 | 0.75705 | 3 | 0 | 3 |
| C11orf86 | PLA2G4F | 0.750853 | 3 | 0 | 3 |
| C11orf86 | SP6 | 0.749546 | 3 | 0 | 3 |
| C11orf86 | OPTC | 0.748702 | 3 | 0 | 3 |
| C11orf86 | CELF3 | 0.743764 | 4 | 0 | 4 |
| C11orf86 | PHF7 | 0.74357 | 3 | 0 | 3 |
| C11orf86 | BCKDHA | 0.741363 | 3 | 0 | 3 |
| C11orf86 | IZUMO2 | 0.736931 | 3 | 0 | 3 |
| C11orf86 | SERPINA10 | 0.735552 | 3 | 0 | 3 |
| C11orf86 | OR2C1 | 0.735483 | 3 | 0 | 3 |
| C11orf86 | PNPLA2 | 0.734608 | 3 | 0 | 3 |
| C11orf86 | NPEPL1 | 0.725343 | 4 | 0 | 4 |
| C11orf86 | PTPRN | 0.724747 | 4 | 0 | 4 |
| C11orf86 | CHST13 | 0.719692 | 3 | 0 | 3 |
| C11orf86 | KRTAP4-8 | 0.713947 | 3 | 0 | 3 |
| C11orf86 | TM6SF2 | 0.713437 | 3 | 0 | 3 |
For details and further investigation, click here
