| Full name: choline dehydrogenase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 55349 | HGNC ID: HGNC:24288 | Ensembl Gene: ENSG00000016391 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CHDH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHDH | 55349 | 1559591_s_at | -0.0612 | 0.8953 | |
| GSE26886 | CHDH | 55349 | 228560_at | -0.0195 | 0.9425 | |
| GSE45670 | CHDH | 55349 | 1559591_s_at | -0.1237 | 0.2698 | |
| GSE53622 | CHDH | 55349 | 81805 | 0.1044 | 0.5185 | |
| GSE53624 | CHDH | 55349 | 81805 | -0.0136 | 0.9248 | |
| GSE63941 | CHDH | 55349 | 230484_at | 0.0433 | 0.8158 | |
| GSE77861 | CHDH | 55349 | 1559591_s_at | -0.1263 | 0.3047 | |
| GSE97050 | CHDH | 55349 | A_23_P69293 | 0.2475 | 0.2950 | |
| SRP007169 | CHDH | 55349 | RNAseq | 0.2461 | 0.7449 | |
| SRP064894 | CHDH | 55349 | RNAseq | -0.1780 | 0.5199 | |
| SRP133303 | CHDH | 55349 | RNAseq | -0.1996 | 0.3198 | |
| SRP159526 | CHDH | 55349 | RNAseq | 1.2305 | 0.0532 | |
| SRP193095 | CHDH | 55349 | RNAseq | -0.1065 | 0.7389 | |
| SRP219564 | CHDH | 55349 | RNAseq | 0.4330 | 0.3692 | |
| TCGA | CHDH | 55349 | RNAseq | -1.0772 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CHDH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHDH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHDH | 55349 | 0 | 17 | 13 | |
| GSE20123 | CHDH | 55349 | 0 | 18 | 12 | |
| GSE43470 | CHDH | 55349 | 0 | 18 | 25 | |
| GSE46452 | CHDH | 55349 | 2 | 17 | 40 | |
| GSE47630 | CHDH | 55349 | 1 | 24 | 15 | |
| GSE54993 | CHDH | 55349 | 6 | 2 | 62 | |
| GSE54994 | CHDH | 55349 | 0 | 32 | 21 | |
| GSE60625 | CHDH | 55349 | 5 | 0 | 6 | |
| GSE74703 | CHDH | 55349 | 0 | 14 | 22 | |
| GSE74704 | CHDH | 55349 | 0 | 12 | 8 | |
| TCGA | CHDH | 55349 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 232; Total Number of normals: 242.
Somatic mutations of CHDH:
Generating mutation plots.
Highly correlated genes for CHDH:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHDH | SLC26A1 | 0.752536 | 3 | 0 | 3 |
| CHDH | CDHR2 | 0.748876 | 3 | 0 | 3 |
| CHDH | CABP1 | 0.721621 | 3 | 0 | 3 |
| CHDH | ZNF230 | 0.703307 | 3 | 0 | 3 |
| CHDH | MEGF11 | 0.702887 | 3 | 0 | 3 |
| CHDH | ZC3H10 | 0.698208 | 3 | 0 | 3 |
| CHDH | VRTN | 0.684629 | 3 | 0 | 3 |
| CHDH | DDC | 0.681827 | 4 | 0 | 4 |
| CHDH | PTGDR2 | 0.681485 | 3 | 0 | 3 |
| CHDH | CHD5 | 0.678163 | 3 | 0 | 3 |
| CHDH | GYPE | 0.673741 | 3 | 0 | 3 |
| CHDH | IL26 | 0.672548 | 3 | 0 | 3 |
| CHDH | IQCD | 0.671804 | 3 | 0 | 3 |
| CHDH | GABRB3 | 0.671703 | 3 | 0 | 3 |
| CHDH | TNR | 0.660235 | 3 | 0 | 3 |
| CHDH | IL17RC | 0.6376 | 3 | 0 | 3 |
| CHDH | BTBD19 | 0.636449 | 4 | 0 | 3 |
| CHDH | EPHA10 | 0.632736 | 4 | 0 | 3 |
| CHDH | IL9R | 0.620426 | 4 | 0 | 3 |
| CHDH | CLECL1 | 0.607505 | 4 | 0 | 3 |
For details and further investigation, click here
