| Full name: cripto, FRL-1, cryptic family 1B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 653275 | HGNC ID: HGNC:33983 | Ensembl Gene: ENSG00000152093 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CFC1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CFC1B | 653275 | 228878_s_at | -0.0136 | 0.9637 | |
| GSE26886 | CFC1B | 653275 | 228878_s_at | 0.1358 | 0.1079 | |
| GSE45670 | CFC1B | 653275 | 228878_s_at | 0.0634 | 0.4355 | |
| GSE63941 | CFC1B | 653275 | 228878_s_at | -0.1056 | 0.5223 | |
| GSE77861 | CFC1B | 653275 | 228878_s_at | -0.0150 | 0.9391 | |
| TCGA | CFC1B | 653275 | RNAseq | -7.0090 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CFC1B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CFC1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CFC1B | 653275 | 5 | 3 | 22 | |
| GSE20123 | CFC1B | 653275 | 5 | 3 | 22 | |
| GSE43470 | CFC1B | 653275 | 2 | 2 | 39 | |
| GSE46452 | CFC1B | 653275 | 1 | 3 | 55 | |
| GSE47630 | CFC1B | 653275 | 5 | 0 | 35 | |
| GSE54993 | CFC1B | 653275 | 0 | 6 | 64 | |
| GSE54994 | CFC1B | 653275 | 10 | 0 | 43 | |
| GSE60625 | CFC1B | 653275 | 0 | 3 | 8 | |
| GSE74703 | CFC1B | 653275 | 2 | 1 | 33 | |
| GSE74704 | CFC1B | 653275 | 3 | 1 | 16 | |
| TCGA | CFC1B | 653275 | 22 | 9 | 65 |
Total number of gains: 55; Total number of losses: 31; Total Number of normals: 402.
Somatic mutations of CFC1B:
Generating mutation plots.
Highly correlated genes for CFC1B:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CFC1B | SPATA21 | 0.720643 | 3 | 0 | 3 |
| CFC1B | BIRC7 | 0.671489 | 3 | 0 | 3 |
| CFC1B | DNAH9 | 0.667786 | 3 | 0 | 3 |
| CFC1B | NPPB | 0.657606 | 3 | 0 | 3 |
| CFC1B | NXF5 | 0.642287 | 3 | 0 | 3 |
| CFC1B | VRTN | 0.629202 | 3 | 0 | 3 |
| CFC1B | PGLYRP1 | 0.62233 | 3 | 0 | 3 |
| CFC1B | PDCD1 | 0.622108 | 3 | 0 | 3 |
| CFC1B | WT1 | 0.621121 | 3 | 0 | 3 |
| CFC1B | LINC00851 | 0.615951 | 3 | 0 | 3 |
| CFC1B | SCUBE1 | 0.613483 | 3 | 0 | 3 |
| CFC1B | CST9 | 0.607344 | 4 | 0 | 3 |
| CFC1B | C1QTNF1-AS1 | 0.607059 | 3 | 0 | 3 |
| CFC1B | TSSK4 | 0.594814 | 3 | 0 | 3 |
| CFC1B | FAM153A | 0.594199 | 4 | 0 | 3 |
| CFC1B | FGL1 | 0.588646 | 3 | 0 | 3 |
| CFC1B | OR1F1 | 0.585427 | 3 | 0 | 3 |
| CFC1B | IQCC | 0.580882 | 4 | 0 | 3 |
| CFC1B | SLC22A7 | 0.576143 | 3 | 0 | 3 |
| CFC1B | GRIN1 | 0.565538 | 4 | 0 | 3 |
For details and further investigation, click here
