| Full name: testis specific serine kinase 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 283629 | HGNC ID: HGNC:19825 | Ensembl Gene: ENSG00000139908 | OMIM ID: 610711 |
| Drug and gene relationship at DGIdb | |||
Expression of TSSK4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSSK4 | 283629 | 242595_at | 0.0606 | 0.8103 | |
| GSE26886 | TSSK4 | 283629 | 242595_at | 0.0498 | 0.6456 | |
| GSE45670 | TSSK4 | 283629 | 242595_at | 0.0989 | 0.2283 | |
| GSE53622 | TSSK4 | 283629 | 10343 | 0.1722 | 0.0034 | |
| GSE53624 | TSSK4 | 283629 | 10343 | 0.3186 | 0.0000 | |
| GSE63941 | TSSK4 | 283629 | 242595_at | 0.1519 | 0.2752 | |
| GSE77861 | TSSK4 | 283629 | 242595_at | 0.0135 | 0.8905 | |
| GSE97050 | TSSK4 | 283629 | A_24_P352637 | 0.2782 | 0.3495 | |
| SRP133303 | TSSK4 | 283629 | RNAseq | -0.0052 | 0.9848 | |
| SRP159526 | TSSK4 | 283629 | RNAseq | -0.6541 | 0.0312 | |
| SRP193095 | TSSK4 | 283629 | RNAseq | 0.2124 | 0.1643 | |
| SRP219564 | TSSK4 | 283629 | RNAseq | -0.6404 | 0.1816 | |
| TCGA | TSSK4 | 283629 | RNAseq | -0.3423 | 0.0320 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSSK4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSSK4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSSK4 | 283629 | 8 | 3 | 19 | |
| GSE20123 | TSSK4 | 283629 | 8 | 3 | 19 | |
| GSE43470 | TSSK4 | 283629 | 8 | 2 | 33 | |
| GSE46452 | TSSK4 | 283629 | 16 | 2 | 41 | |
| GSE47630 | TSSK4 | 283629 | 11 | 10 | 19 | |
| GSE54993 | TSSK4 | 283629 | 3 | 11 | 56 | |
| GSE54994 | TSSK4 | 283629 | 18 | 5 | 30 | |
| GSE60625 | TSSK4 | 283629 | 0 | 2 | 9 | |
| GSE74703 | TSSK4 | 283629 | 7 | 2 | 27 | |
| GSE74704 | TSSK4 | 283629 | 3 | 2 | 15 | |
| TCGA | TSSK4 | 283629 | 27 | 13 | 56 |
Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.
Somatic mutations of TSSK4:
Generating mutation plots.
Highly correlated genes for TSSK4:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSSK4 | OR2C3 | 0.69177 | 3 | 0 | 3 |
| TSSK4 | PRLH | 0.691729 | 3 | 0 | 3 |
| TSSK4 | MEGF10 | 0.66234 | 3 | 0 | 3 |
| TSSK4 | C19orf81 | 0.65915 | 3 | 0 | 3 |
| TSSK4 | CLEC1B | 0.65774 | 3 | 0 | 3 |
| TSSK4 | GABRB1 | 0.648609 | 3 | 0 | 3 |
| TSSK4 | PDIA2 | 0.630124 | 3 | 0 | 3 |
| TSSK4 | NPPB | 0.620318 | 4 | 0 | 3 |
| TSSK4 | MC3R | 0.619885 | 4 | 0 | 3 |
| TSSK4 | MAT1A | 0.605751 | 4 | 0 | 3 |
| TSSK4 | CFC1B | 0.594814 | 3 | 0 | 3 |
| TSSK4 | CPN1 | 0.59464 | 4 | 0 | 3 |
| TSSK4 | FOXB1 | 0.578019 | 4 | 0 | 3 |
| TSSK4 | AQP4 | 0.569594 | 4 | 0 | 3 |
| TSSK4 | C2orf72 | 0.556726 | 5 | 0 | 3 |
| TSSK4 | FGF22 | 0.556714 | 6 | 0 | 4 |
| TSSK4 | CBLN4 | 0.550092 | 5 | 0 | 3 |
| TSSK4 | LTK | 0.546699 | 5 | 0 | 3 |
| TSSK4 | CYP2D6 | 0.545214 | 4 | 0 | 3 |
| TSSK4 | PRKCG | 0.535123 | 5 | 0 | 3 |
For details and further investigation, click here
