| Full name: baculoviral IAP repeat containing 7 | Alias Symbol: mliap|ML-IAP|KIAP|RNF50 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 79444 | HGNC ID: HGNC:13702 | Ensembl Gene: ENSG00000101197 | OMIM ID: 605737 |
| Drug and gene relationship at DGIdb | |||
BIRC7 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05145 | Toxoplasmosis | |
| hsa05200 | Pathways in cancer | |
| hsa05222 | Small cell lung cancer |
Expression of BIRC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BIRC7 | 79444 | 220451_s_at | 0.1490 | 0.6901 | |
| GSE20347 | BIRC7 | 79444 | 220451_s_at | 0.0005 | 0.9972 | |
| GSE23400 | BIRC7 | 79444 | 220451_s_at | -0.1786 | 0.0000 | |
| GSE26886 | BIRC7 | 79444 | 220451_s_at | 0.1303 | 0.4350 | |
| GSE29001 | BIRC7 | 79444 | 220451_s_at | 0.1165 | 0.5673 | |
| GSE38129 | BIRC7 | 79444 | 220451_s_at | -0.0923 | 0.2490 | |
| GSE45670 | BIRC7 | 79444 | 220451_s_at | 0.0135 | 0.9097 | |
| GSE53622 | BIRC7 | 79444 | 5917 | 0.0864 | 0.2492 | |
| GSE53624 | BIRC7 | 79444 | 5917 | 0.0218 | 0.7514 | |
| GSE63941 | BIRC7 | 79444 | 220451_s_at | -0.1781 | 0.4584 | |
| GSE77861 | BIRC7 | 79444 | 220451_s_at | -0.1482 | 0.3284 | |
| TCGA | BIRC7 | 79444 | RNAseq | 2.7744 | 0.0176 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BIRC7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BIRC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BIRC7 | 79444 | 14 | 2 | 14 | |
| GSE20123 | BIRC7 | 79444 | 14 | 2 | 14 | |
| GSE43470 | BIRC7 | 79444 | 11 | 1 | 31 | |
| GSE46452 | BIRC7 | 79444 | 35 | 0 | 24 | |
| GSE47630 | BIRC7 | 79444 | 25 | 1 | 14 | |
| GSE54993 | BIRC7 | 79444 | 0 | 17 | 53 | |
| GSE54994 | BIRC7 | 79444 | 29 | 0 | 24 | |
| GSE60625 | BIRC7 | 79444 | 0 | 0 | 11 | |
| GSE74703 | BIRC7 | 79444 | 10 | 0 | 26 | |
| GSE74704 | BIRC7 | 79444 | 11 | 0 | 9 | |
| TCGA | BIRC7 | 79444 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of BIRC7:
Generating mutation plots.
Highly correlated genes for BIRC7:
Showing top 20/597 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BIRC7 | C19orf81 | 0.757685 | 3 | 0 | 3 |
| BIRC7 | DNAJC4 | 0.733173 | 3 | 0 | 3 |
| BIRC7 | OPRK1 | 0.730789 | 3 | 0 | 3 |
| BIRC7 | DERL3 | 0.712563 | 3 | 0 | 3 |
| BIRC7 | ATF5 | 0.711197 | 3 | 0 | 3 |
| BIRC7 | KCNH6 | 0.71058 | 5 | 0 | 5 |
| BIRC7 | TONSL | 0.7105 | 3 | 0 | 3 |
| BIRC7 | NAT8B | 0.70256 | 4 | 0 | 4 |
| BIRC7 | NOS2 | 0.694749 | 3 | 0 | 3 |
| BIRC7 | APOC2 | 0.690958 | 3 | 0 | 3 |
| BIRC7 | KCNF1 | 0.684934 | 6 | 0 | 5 |
| BIRC7 | CITED1 | 0.680712 | 3 | 0 | 3 |
| BIRC7 | IGH | 0.678287 | 7 | 0 | 6 |
| BIRC7 | VGF | 0.675682 | 5 | 0 | 5 |
| BIRC7 | SLC22A2 | 0.675112 | 3 | 0 | 3 |
| BIRC7 | KCNG3 | 0.674771 | 3 | 0 | 3 |
| BIRC7 | CFC1B | 0.671489 | 3 | 0 | 3 |
| BIRC7 | FMN2 | 0.665392 | 3 | 0 | 3 |
| BIRC7 | NFKBIB | 0.664252 | 3 | 0 | 3 |
| BIRC7 | PAPOLB | 0.660439 | 3 | 0 | 3 |
For details and further investigation, click here
