| Full name: chromatin accessibility complex subunit 1 | Alias Symbol: CHRAC15|YCL1 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 54108 | HGNC ID: HGNC:13544 | Ensembl Gene: ENSG00000104472 | OMIM ID: 607268 |
| Drug and gene relationship at DGIdb | |||
Expression of CHRAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHRAC1 | 54108 | 231764_at | 0.2344 | 0.5217 | |
| GSE26886 | CHRAC1 | 54108 | 231764_at | 0.4491 | 0.0423 | |
| GSE45670 | CHRAC1 | 54108 | 231764_at | 0.0607 | 0.7835 | |
| GSE53622 | CHRAC1 | 54108 | 101568 | 0.4060 | 0.0000 | |
| GSE53624 | CHRAC1 | 54108 | 101568 | 0.4417 | 0.0000 | |
| GSE63941 | CHRAC1 | 54108 | 231764_at | 0.0401 | 0.9393 | |
| GSE77861 | CHRAC1 | 54108 | 231764_at | -0.0957 | 0.6947 | |
| GSE97050 | CHRAC1 | 54108 | A_33_P3400263 | -0.5855 | 0.1095 | |
| SRP007169 | CHRAC1 | 54108 | RNAseq | -0.1001 | 0.7697 | |
| SRP008496 | CHRAC1 | 54108 | RNAseq | 0.2995 | 0.1440 | |
| SRP064894 | CHRAC1 | 54108 | RNAseq | 0.7614 | 0.0000 | |
| SRP133303 | CHRAC1 | 54108 | RNAseq | 0.5463 | 0.0015 | |
| SRP159526 | CHRAC1 | 54108 | RNAseq | 0.2744 | 0.2716 | |
| SRP193095 | CHRAC1 | 54108 | RNAseq | 0.5568 | 0.0011 | |
| SRP219564 | CHRAC1 | 54108 | RNAseq | 0.4591 | 0.2181 | |
| TCGA | CHRAC1 | 54108 | RNAseq | 0.1929 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CHRAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHRAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHRAC1 | 54108 | 16 | 0 | 14 | |
| GSE20123 | CHRAC1 | 54108 | 16 | 0 | 14 | |
| GSE43470 | CHRAC1 | 54108 | 22 | 2 | 19 | |
| GSE46452 | CHRAC1 | 54108 | 27 | 0 | 32 | |
| GSE47630 | CHRAC1 | 54108 | 24 | 0 | 16 | |
| GSE54993 | CHRAC1 | 54108 | 0 | 25 | 45 | |
| GSE54994 | CHRAC1 | 54108 | 39 | 1 | 13 | |
| GSE60625 | CHRAC1 | 54108 | 3 | 4 | 4 | |
| GSE74703 | CHRAC1 | 54108 | 19 | 1 | 16 | |
| GSE74704 | CHRAC1 | 54108 | 10 | 0 | 10 | |
| TCGA | CHRAC1 | 54108 | 65 | 2 | 29 |
Total number of gains: 241; Total number of losses: 35; Total Number of normals: 212.
Somatic mutations of CHRAC1:
Generating mutation plots.
Highly correlated genes for CHRAC1:
Showing top 20/26 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHRAC1 | RWDD3 | 0.676843 | 3 | 0 | 3 |
| CHRAC1 | CCAR2 | 0.645466 | 3 | 0 | 3 |
| CHRAC1 | ZDHHC22 | 0.644375 | 3 | 0 | 3 |
| CHRAC1 | MYBPC1 | 0.610239 | 4 | 0 | 3 |
| CHRAC1 | TRAPPC9 | 0.609089 | 4 | 0 | 3 |
| CHRAC1 | HOXC9 | 0.601659 | 3 | 0 | 3 |
| CHRAC1 | LAMA5 | 0.59876 | 3 | 0 | 3 |
| CHRAC1 | CHGB | 0.598305 | 3 | 0 | 3 |
| CHRAC1 | ATP7B | 0.593865 | 5 | 0 | 4 |
| CHRAC1 | CCDC122 | 0.587747 | 4 | 0 | 3 |
| CHRAC1 | ZNF26 | 0.563775 | 4 | 0 | 3 |
| CHRAC1 | C11orf95 | 0.552672 | 3 | 0 | 3 |
| CHRAC1 | FAM24B | 0.55028 | 4 | 0 | 3 |
| CHRAC1 | KLHL35 | 0.541416 | 4 | 0 | 3 |
| CHRAC1 | GTF2IRD2 | 0.538544 | 4 | 0 | 3 |
| CHRAC1 | FBRSL1 | 0.537818 | 4 | 0 | 3 |
| CHRAC1 | TTC33 | 0.536361 | 3 | 0 | 3 |
| CHRAC1 | ACVR2B | 0.534718 | 4 | 0 | 3 |
| CHRAC1 | ZNF511 | 0.531215 | 5 | 0 | 3 |
| CHRAC1 | BMPR1B | 0.527968 | 4 | 0 | 4 |
For details and further investigation, click here
