| Full name: myosin binding protein C, slow type | Alias Symbol: ssMyBP-C | ||
| Type: protein-coding gene | Cytoband: 12q23.2 | ||
| Entrez ID: 4604 | HGNC ID: HGNC:7549 | Ensembl Gene: ENSG00000196091 | OMIM ID: 160794 |
| Drug and gene relationship at DGIdb | |||
Expression of MYBPC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYBPC1 | 4604 | 214087_s_at | 0.3075 | 0.8993 | |
| GSE20347 | MYBPC1 | 4604 | 214087_s_at | 0.6667 | 0.2135 | |
| GSE23400 | MYBPC1 | 4604 | 214087_s_at | 0.0654 | 0.4536 | |
| GSE26886 | MYBPC1 | 4604 | 214087_s_at | 0.7233 | 0.2224 | |
| GSE29001 | MYBPC1 | 4604 | 214087_s_at | 0.4688 | 0.3687 | |
| GSE38129 | MYBPC1 | 4604 | 214087_s_at | 0.1561 | 0.5836 | |
| GSE45670 | MYBPC1 | 4604 | 214087_s_at | -0.0668 | 0.5705 | |
| GSE53622 | MYBPC1 | 4604 | 74027 | 0.3090 | 0.1696 | |
| GSE53624 | MYBPC1 | 4604 | 74027 | 0.0459 | 0.7944 | |
| GSE63941 | MYBPC1 | 4604 | 214087_s_at | -0.2312 | 0.0670 | |
| GSE77861 | MYBPC1 | 4604 | 214087_s_at | -0.0985 | 0.2969 | |
| GSE97050 | MYBPC1 | 4604 | A_23_P128362 | -2.0668 | 0.2333 | |
| TCGA | MYBPC1 | 4604 | RNAseq | -1.5145 | 0.2745 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYBPC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYBPC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYBPC1 | 4604 | 2 | 2 | 26 | |
| GSE20123 | MYBPC1 | 4604 | 2 | 2 | 26 | |
| GSE43470 | MYBPC1 | 4604 | 2 | 0 | 41 | |
| GSE46452 | MYBPC1 | 4604 | 9 | 1 | 49 | |
| GSE47630 | MYBPC1 | 4604 | 9 | 1 | 30 | |
| GSE54993 | MYBPC1 | 4604 | 0 | 5 | 65 | |
| GSE54994 | MYBPC1 | 4604 | 4 | 2 | 47 | |
| GSE60625 | MYBPC1 | 4604 | 0 | 0 | 11 | |
| GSE74703 | MYBPC1 | 4604 | 2 | 0 | 34 | |
| GSE74704 | MYBPC1 | 4604 | 1 | 2 | 17 | |
| TCGA | MYBPC1 | 4604 | 18 | 10 | 68 |
Total number of gains: 49; Total number of losses: 25; Total Number of normals: 414.
Somatic mutations of MYBPC1:
Generating mutation plots.
Highly correlated genes for MYBPC1:
Showing top 20/60 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYBPC1 | FGF3 | 0.817862 | 5 | 0 | 5 |
| MYBPC1 | GRIA2 | 0.805596 | 3 | 0 | 3 |
| MYBPC1 | ART3 | 0.795382 | 3 | 0 | 3 |
| MYBPC1 | NPTX2 | 0.787934 | 4 | 0 | 4 |
| MYBPC1 | CSN3 | 0.744281 | 4 | 0 | 3 |
| MYBPC1 | PPP1R9A | 0.728914 | 3 | 0 | 3 |
| MYBPC1 | ATP7B | 0.686988 | 4 | 0 | 3 |
| MYBPC1 | MB | 0.682844 | 5 | 0 | 4 |
| MYBPC1 | TRAM1L1 | 0.681757 | 3 | 0 | 3 |
| MYBPC1 | ABCA3 | 0.660669 | 4 | 0 | 4 |
| MYBPC1 | DACH1 | 0.656957 | 3 | 0 | 3 |
| MYBPC1 | MYCN | 0.651771 | 6 | 0 | 4 |
| MYBPC1 | TCEANC | 0.640938 | 3 | 0 | 3 |
| MYBPC1 | YPEL1 | 0.633059 | 3 | 0 | 3 |
| MYBPC1 | DAG1 | 0.630789 | 3 | 0 | 3 |
| MYBPC1 | MYOM3 | 0.616363 | 3 | 0 | 3 |
| MYBPC1 | CHRAC1 | 0.610239 | 4 | 0 | 3 |
| MYBPC1 | SLC41A3 | 0.60846 | 5 | 0 | 4 |
| MYBPC1 | ACSS3 | 0.60787 | 4 | 0 | 3 |
| MYBPC1 | PHKA2 | 0.597746 | 4 | 0 | 3 |
For details and further investigation, click here
