| Full name: GTF2I repeat domain containing 2 | Alias Symbol: FLJ37938|GTF2IRD2A | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 84163 | HGNC ID: HGNC:30775 | Ensembl Gene: ENSG00000196275 | OMIM ID: 608899 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GTF2IRD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2IRD2 | 84163 | 228765_at | 0.8650 | 0.0777 | |
| GSE26886 | GTF2IRD2 | 84163 | 228765_at | 1.8724 | 0.0000 | |
| GSE45670 | GTF2IRD2 | 84163 | 228765_at | 0.6627 | 0.0158 | |
| GSE53622 | GTF2IRD2 | 84163 | 2310 | 0.6472 | 0.0000 | |
| GSE53624 | GTF2IRD2 | 84163 | 2310 | 0.9487 | 0.0000 | |
| GSE63941 | GTF2IRD2 | 84163 | 228765_at | 1.6011 | 0.0030 | |
| GSE77861 | GTF2IRD2 | 84163 | 228765_at | 0.3935 | 0.0975 | |
| GSE97050 | GTF2IRD2 | 84163 | A_23_P59616 | -0.1281 | 0.6553 | |
| SRP007169 | GTF2IRD2 | 84163 | RNAseq | 0.4481 | 0.6326 | |
| SRP008496 | GTF2IRD2 | 84163 | RNAseq | 0.2076 | 0.8545 | |
| SRP064894 | GTF2IRD2 | 84163 | RNAseq | 0.8657 | 0.0012 | |
| SRP133303 | GTF2IRD2 | 84163 | RNAseq | 0.0901 | 0.7191 | |
| SRP159526 | GTF2IRD2 | 84163 | RNAseq | 1.5632 | 0.0017 | |
| SRP193095 | GTF2IRD2 | 84163 | RNAseq | 0.6484 | 0.0006 | |
| SRP219564 | GTF2IRD2 | 84163 | RNAseq | 0.3063 | 0.5456 | |
| TCGA | GTF2IRD2 | 84163 | RNAseq | -0.5272 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GTF2IRD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2IRD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2IRD2 | 84163 | 14 | 1 | 15 | |
| GSE20123 | GTF2IRD2 | 84163 | 14 | 1 | 15 | |
| GSE43470 | GTF2IRD2 | 84163 | 3 | 2 | 38 | |
| GSE46452 | GTF2IRD2 | 84163 | 12 | 0 | 47 | |
| GSE47630 | GTF2IRD2 | 84163 | 7 | 2 | 31 | |
| GSE54993 | GTF2IRD2 | 84163 | 2 | 7 | 61 | |
| GSE54994 | GTF2IRD2 | 84163 | 13 | 3 | 37 | |
| GSE60625 | GTF2IRD2 | 84163 | 0 | 0 | 11 | |
| GSE74703 | GTF2IRD2 | 84163 | 3 | 1 | 32 | |
| GSE74704 | GTF2IRD2 | 84163 | 8 | 1 | 11 | |
| TCGA | GTF2IRD2 | 84163 | 44 | 7 | 45 |
Total number of gains: 120; Total number of losses: 25; Total Number of normals: 343.
Somatic mutations of GTF2IRD2:
Generating mutation plots.
Highly correlated genes for GTF2IRD2:
Showing top 20/546 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2IRD2 | ZNF446 | 0.825461 | 3 | 0 | 3 |
| GTF2IRD2 | SHC2 | 0.811857 | 3 | 0 | 3 |
| GTF2IRD2 | ARHGAP22 | 0.796848 | 3 | 0 | 3 |
| GTF2IRD2 | ALKBH5 | 0.788962 | 3 | 0 | 3 |
| GTF2IRD2 | TOX2 | 0.787627 | 3 | 0 | 3 |
| GTF2IRD2 | MYH9 | 0.786311 | 3 | 0 | 3 |
| GTF2IRD2 | EML6 | 0.782139 | 3 | 0 | 3 |
| GTF2IRD2 | DOHH | 0.779376 | 3 | 0 | 3 |
| GTF2IRD2 | KLHL26 | 0.771146 | 3 | 0 | 3 |
| GTF2IRD2 | ZNF428 | 0.7695 | 3 | 0 | 3 |
| GTF2IRD2 | CNOT3 | 0.764334 | 4 | 0 | 4 |
| GTF2IRD2 | SYCE1L | 0.763564 | 3 | 0 | 3 |
| GTF2IRD2 | STK32C | 0.759533 | 3 | 0 | 3 |
| GTF2IRD2 | HIRIP3 | 0.759477 | 3 | 0 | 3 |
| GTF2IRD2 | MAPK8IP2 | 0.759185 | 3 | 0 | 3 |
| GTF2IRD2 | ETV3 | 0.755445 | 3 | 0 | 3 |
| GTF2IRD2 | NKX2-8 | 0.753202 | 3 | 0 | 3 |
| GTF2IRD2 | POLD1 | 0.74828 | 6 | 0 | 6 |
| GTF2IRD2 | FBRSL1 | 0.746431 | 5 | 0 | 4 |
| GTF2IRD2 | KLRG2 | 0.734529 | 3 | 0 | 3 |
For details and further investigation, click here
