| Full name: cell cycle and apoptosis regulator 2 | Alias Symbol: DBC-1|DBC1|NET35 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 57805 | HGNC ID: HGNC:23360 | Ensembl Gene: ENSG00000158941 | OMIM ID: 607359 |
| Drug and gene relationship at DGIdb | |||
Expression of CCAR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCAR2 | 57805 | 225187_at | 0.6253 | 0.1346 | |
| GSE20347 | CCAR2 | 57805 | 221070_s_at | 0.0029 | 0.9694 | |
| GSE23400 | CCAR2 | 57805 | 221070_s_at | -0.0464 | 0.0090 | |
| GSE26886 | CCAR2 | 57805 | 225193_at | 1.1787 | 0.0041 | |
| GSE29001 | CCAR2 | 57805 | 221070_s_at | -0.0693 | 0.4107 | |
| GSE38129 | CCAR2 | 57805 | 221070_s_at | -0.0593 | 0.2200 | |
| GSE45670 | CCAR2 | 57805 | 225187_at | 0.5270 | 0.0007 | |
| GSE53622 | CCAR2 | 57805 | 26010 | 0.1494 | 0.0633 | |
| GSE53624 | CCAR2 | 57805 | 26010 | 0.1283 | 0.2429 | |
| GSE63941 | CCAR2 | 57805 | 225193_at | 1.2110 | 0.0338 | |
| GSE77861 | CCAR2 | 57805 | 225187_at | 0.3723 | 0.0466 | |
| SRP007169 | CCAR2 | 57805 | RNAseq | 0.6647 | 0.1065 | |
| SRP008496 | CCAR2 | 57805 | RNAseq | 0.5869 | 0.0179 | |
| SRP064894 | CCAR2 | 57805 | RNAseq | 0.2158 | 0.1296 | |
| SRP133303 | CCAR2 | 57805 | RNAseq | -0.1564 | 0.4211 | |
| SRP159526 | CCAR2 | 57805 | RNAseq | 0.3158 | 0.3069 | |
| SRP193095 | CCAR2 | 57805 | RNAseq | 0.1336 | 0.2653 | |
| SRP219564 | CCAR2 | 57805 | RNAseq | 0.1187 | 0.6837 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCAR2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCAR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCAR2 | 57805 | 4 | 10 | 16 | |
| GSE20123 | CCAR2 | 57805 | 4 | 10 | 16 | |
| GSE43470 | CCAR2 | 57805 | 4 | 9 | 30 | |
| GSE46452 | CCAR2 | 57805 | 13 | 13 | 33 | |
| GSE47630 | CCAR2 | 57805 | 10 | 8 | 22 | |
| GSE54993 | CCAR2 | 57805 | 2 | 14 | 54 | |
| GSE54994 | CCAR2 | 57805 | 10 | 17 | 26 | |
| GSE60625 | CCAR2 | 57805 | 3 | 0 | 8 | |
| GSE74703 | CCAR2 | 57805 | 4 | 7 | 25 | |
| GSE74704 | CCAR2 | 57805 | 3 | 7 | 10 |
Total number of gains: 57; Total number of losses: 95; Total Number of normals: 240.
Somatic mutations of CCAR2:
Generating mutation plots.
Highly correlated genes for CCAR2:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCAR2 | CDCA2 | 0.731259 | 3 | 0 | 3 |
| CCAR2 | SIX4 | 0.708927 | 4 | 0 | 4 |
| CCAR2 | TSFM | 0.684099 | 5 | 0 | 4 |
| CCAR2 | XRCC6 | 0.67854 | 3 | 0 | 3 |
| CCAR2 | ALG1 | 0.672117 | 4 | 0 | 4 |
| CCAR2 | NEDD1 | 0.64676 | 3 | 0 | 3 |
| CCAR2 | CHRAC1 | 0.645466 | 3 | 0 | 3 |
| CCAR2 | TMEM208 | 0.644682 | 3 | 0 | 3 |
| CCAR2 | APMAP | 0.643907 | 4 | 0 | 3 |
| CCAR2 | MAZ | 0.638119 | 3 | 0 | 3 |
| CCAR2 | HR | 0.636782 | 4 | 0 | 3 |
| CCAR2 | GALNS | 0.624974 | 3 | 0 | 3 |
| CCAR2 | POLR3A | 0.623994 | 3 | 0 | 3 |
| CCAR2 | MRGBP | 0.623764 | 4 | 0 | 4 |
| CCAR2 | NOC4L | 0.623432 | 3 | 0 | 3 |
| CCAR2 | RCC2 | 0.621003 | 5 | 0 | 4 |
| CCAR2 | SLC7A6OS | 0.620163 | 4 | 0 | 3 |
| CCAR2 | CPNE8 | 0.617914 | 3 | 0 | 3 |
| CCAR2 | SSRP1 | 0.6161 | 5 | 0 | 3 |
| CCAR2 | AUNIP | 0.612818 | 3 | 0 | 3 |
For details and further investigation, click here
